Results 21 to 30 of about 399,518 (261)

Psychrobacter sanguinis Wound Infection Associated with Marine Environment Exposure, Washington, USA

Emerging Infectious Diseases, 2018
We report a 26-year-old man with Psychrobacter sanguinis cellulitis of a wound sustained during ocean fishing in Washington, USA, in 2017. Psychrobacter spp. are opportunistic pathogens found in a wide range of environments. Clinicians should be aware of
Jesse Bonwitt, Michael Tran, Angela Droz, Anna Gonzalez, William A. Glover   +4 more
doaj   +1 more source

Ribosomal Proteins in Ribosome Assembly

Biomolecules
Ribosomes are the cellular machinery responsible for translating mRNA into proteins, a process fundamental to all domains of life from bacteria to eukaryotes [...]
Brigitte Pertschy, Ingrid Zierler
openaire   +4 more sources

The Modular Adaptive Ribosome. [PDF]

PLoS ONE, 2016
The ribosome is an ancient machine, performing the same function across organisms. Although functionally unitary, recent experiments suggest specialized roles for some ribosomal proteins.
Anupama Yadav, Aparna Radhakrishnan, Anshuman Panda, Amartya Singh, Himanshu Sinha, Gyan Bhanot   +5 more
doaj   +1 more source

Copy Number of Human Ribosomal Genes With Aging: Unchanged Mean, but Narrowed Range and Decreased Variance in Elderly Group

Frontiers in Genetics, 2018
Introduction: The multi-copied genes coding for the human 18, 5.8, and 28S ribosomal RNA (rRNA) are located in five pairs of acrocentric chromosomes forming so-called rDNA.
Elena M. Malinovskaya, Elizaveta S. Ershova, Vera E. Golimbet, Lev N. Porokhovnik, Nataliya A. Lyapunova, Serguey I. Kutsev, Natalia N. Veiko, Svetlana V. Kostyuk   +7 more
doaj   +1 more source

Our current understanding of the toxicity of altered mito-ribosomal fidelity during mitochondrial protein synthesis: What can it tell us about human disease?

Frontiers in Physiology, 2023
Altered mito-ribosomal fidelity is an important and insufficiently understood causative agent of mitochondrial dysfunction. Its pathogenic effects are particularly well-known in the case of mitochondrially induced deafness, due to the existence of the ...
Antón Vila-Sanjurjo, Natalia Mallo, John F. Atkins, Joanna L. Elson, Joanna L. Elson, Paul M. Smith   +5 more
doaj   +1 more source

Combined DNA Methylation and Gastric Microbiome Marker Predicts Helicobacter pylori-Negative Gastric Cancer

Gut and Liver
Background/Aims: While DNA methylation and gastric microbiome are each associated with gastric cancer (GC), their combined role in predicting GC remains unclear.
Min-Jeong Kim, Han-Na Kim, Jonathan P. Jacobs, Hyo-Joon Yang   +3 more
doaj   +1 more source

Xenobiotic-induced ribosomal stress compromises dysbiotic gut barrier aging: A one health perspective

Redox Biology, 2023
Upon exposure to internal or environmental insults, ribosomes stand sentinel. In particular, stress-driven dysregulation of ribosomal homeostasis is a potent trigger of adverse outcomes in mammalians.
Junjie Sun, Juil Kim, Hoyoung Jeong, Dasom Kwon, Yuseok Moon   +4 more
doaj   +1 more source

Krüppel-like factor 7 influences translation and pathways involved in ribosomal biogenesis in breast cancer

Breast Cancer Research, 2022
Background Ribosomal biogenesis and ribosomal proteins have attracted attention in the context of tumor biology in recent years. Instead of being mere translational machineries, ribosomes might play an active role in tumor initiation and progression ...
Anne-Marie Lüchtenborg, Patrick Metzger, Miguel Cosenza Contreras, Victor Oria, Martin L. Biniossek, Franziska Lindner, Klemens Fröhlich, Ambrus Malyi, Thalia Erbes, Nicole Gensch, Jochen Maurer, Andreas Thomsen, Melanie Boerries, Oliver Schilling, Martin Werner, Peter Bronsert   +15 more
doaj   +1 more source

The ABCs of the ribosome [PDF]

Nature Structural & Molecular Biology, 2014
An ABC protein that binds the ribosomal exit site suggests a new mechanism for direct regulation of translation in response to changing ATP levels in the cell.
Fredrick, Kurt, Ibba, Michael
openaire   +3 more sources

Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia

Haematologica, 2014
Diamond-Blackfan anemia is a congenital erythroid hypoplasia caused by functional haploinsufficiency of genes encoding ribosomal proteins. Mutations involving the ribosomal protein S19 gene are detected in 25% of patients.
Pekka Jaako, Shubhranshu Debnath, Karin Olsson, Ute Modlich, Michael Rothe, Axel Schambach, Johan Flygare, Stefan Karlsson   +7 more
doaj   +1 more source