Results 221 to 230 of about 516,233 (301)

L‐Cysteine and N‐Acetylcysteine Supplementation Improves Clinical Outcome in a Patient With COXPD10

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT MTO1 is a nuclear gene that encodes a mitochondrial protein essential for modifying mitochondrial transfer RNAs (tRNAs) and stabilizing codon‐anticodon interactions to ensure accurate and efficient mitochondrial protein synthesis and oxidative phosphorylation.
Nishitha R. Pillai, Sara A. Elsbecker, Grace Bronken McCarthy, Kaitlin Weisshappel, Peter Karachunski, Fernando Scaglia   +5 more
wiley   +1 more source

An IscS Persulfide Donates the Sulfur for Ribosomal Protein uL16 Thioamidation

Angewandte Chemie, EarlyView.
YcaO‐catalyzed thioamidation of the ribosomal subunit protein uL16 is widespread in Pseudomonadota bacteria. We identify the iron–sulfur cluster cysteine desulfurase IscS as the sulfur donor via an IscS persulfide and observe direct IscS–uL16 interactions.
Yanqing Xue, Markus W. Voehler, Douglas A. Mitchell   +2 more
wiley   +2 more sources

The Role of ZNF598 in Translational Quality Control: Mechanisms and Emerging Biological Functions. [PDF]

Biology (Basel)
Wu S, Liu Z, Chen G.
europepmc   +1 more source

Structure of the ribosome

Progress in Biophysics and Molecular Biology, 1969
openaire   +2 more sources

Ribosomal Ambiguity

Cold Spring Harbor Symposia on Quantitative Biology, 1966
L, Gorini, G A, Jacoby, L, Breckenridge
openaire   +2 more sources

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +1 more source

eIF5A and polyamines restrict mRNA levels in response to ribosome stalls. [PDF]

Proc Natl Acad Sci U S A
Wohlenberg CM, Monem PC, Barbosa N, Frydman J, Arribere JA.   +4 more
europepmc   +1 more source

Targeting mitochondrial ribosomal proteins: a functional and translational framework for neurodegenerative disease research. [PDF]

Front Neurol
Del Giudice L, Guida M, Aletta MR, Pontieri P.   +3 more
europepmc   +1 more source

Quantifying Viral Lysis in Microalgae Using Cell-Free rRNA. [PDF]

Microbiologyopen
Kikuya S, Tomaru Y, Nagasaki K, Morimoto D, Yamagishi Y, Ogata H, Endo H.   +6 more
europepmc   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +1 more source