Biosynthetic Diversity of Marine-Derived <i>Streptomyces</i> Natural Products: Integrating Genome Mining, Multi-Omics, and Translational Drug Discovery Strategies. [PDF]
Lertcanawanichakul M +7 more
europepmc +1 more source
A Metagenome‐Assembled Genome Catalog From the Global Ruminant Microbiomes
The Ruminant Gastrointestinal MAG Catalog (RGMC) is a comprehensive global resource offering 40,812 strain‐level genomes across 53 bacterial and 4 archaeal classes. It greatly surpasses prior efforts in scale and diversity, serving as an essential foundation for research in ruminant nutrition, microbial function, and methane mitigation.
Shizhe Zhang +8 more
wiley +1 more source
Illuminating ribosome biogenesis disorders through structural biology. [PDF]
Singh S, Lafontaine DLJ.
europepmc +1 more source
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali +10 more
wiley +1 more source
Histopathological evaluation of RPL5 expression in triple-negative breast cancer: an integrated immunohistochemical and transcriptomic study. [PDF]
Zhao B, Yu P, Li L, Zhao Z, Zhang X.
europepmc +1 more source
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu +8 more
wiley +1 more source
Targeting SARS-CoV-2 programmed -1 ribosomal frameshifting: structural dynamics and RNA-directed antiviral strategies. [PDF]
Jeena N, Khan IA.
europepmc +1 more source
Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li +10 more
wiley +1 more source
Integrated phenotypic, histological, transcriptomic, and validation analyses reveal that emaciation syndrome in Plectropomus leopardus is associated with intestinal structural damage, hepatic metabolic remodeling, and muscle protein degradation, highlighting coordinated multi‐tissue alterations underlying disease progression.
Zhihao Zhang +11 more
wiley +1 more source
Genome Sequence and Antimicrobial Production of <i>Pseudomonas crudilactis</i>. [PDF]
McMurphy M +3 more
europepmc +1 more source

