Results 271 to 280 of about 846,528 (387)
PBLD Orchestrates the STING‐Mediated Antiviral Immune Response and Autoimmune Diseases
During viral infection, PBLD expression is downregulated, thereby subverting host antiviral defenses and promoting viral replication. This study identifies PBLD as a positive regulator of STING‐induced type I interferon activation and delineated the molecular network underlying PBLD‐mediated antiviral immunity and autoimmune pathogenesis, highlighting ...
Peili Hou +17 more
wiley +1 more source
The intrinsic properties of mRNAs define their translation efficiency at ribosome shortage. [PDF]
Babaylova ES +4 more
europepmc +1 more source
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning +18 more
wiley +1 more source
Biological Performance and Molecular Mechanisms of Mesyl MicroRNA-Targeted Oligonucleotides in Colorectal Cancer Cells. [PDF]
Miroshnichenko SK +5 more
europepmc +1 more source
tRNA binding modifies the properties of the small ribosomal subunit of rat liver [PDF]
A.M. Reboud, S. Dubost, Jean Paul Reboud
openalex +1 more source
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han +16 more
wiley +1 more source
Towards molecular evolutionary epigenomics with an expanded nucleotide code involving methylated bases. [PDF]
Yoshida S +9 more
europepmc +1 more source

