Results 271 to 280 of about 846,528 (387)

PBLD Orchestrates the STING‐Mediated Antiviral Immune Response and Autoimmune Diseases

open access: yesAdvanced Science, EarlyView.
During viral infection, PBLD expression is downregulated, thereby subverting host antiviral defenses and promoting viral replication. This study identifies PBLD as a positive regulator of STING‐induced type I interferon activation and delineated the molecular network underlying PBLD‐mediated antiviral immunity and autoimmune pathogenesis, highlighting ...
Peili Hou   +17 more
wiley   +1 more source

The intrinsic properties of mRNAs define their translation efficiency at ribosome shortage. [PDF]

open access: yesNucleic Acids Res
Babaylova ES   +4 more
europepmc   +1 more source

Structure of the ribosome

open access: yesProgress in Biophysics and Molecular Biology, 1969
openaire   +2 more sources

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning   +18 more
wiley   +1 more source

Biological Performance and Molecular Mechanisms of Mesyl MicroRNA-Targeted Oligonucleotides in Colorectal Cancer Cells. [PDF]

open access: yesInt J Mol Sci
Miroshnichenko SK   +5 more
europepmc   +1 more source

Bacterial Ribosome

open access: yesBacteriological Reviews, 1970
openaire   +2 more sources

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

open access: yesAdvanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han   +16 more
wiley   +1 more source

Towards molecular evolutionary epigenomics with an expanded nucleotide code involving methylated bases. [PDF]

open access: yesDNA Res
Yoshida S   +9 more
europepmc   +1 more source

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