Results 291 to 300 of about 699,944 (333)

Host Cell Protein Clinical Safety Risk Assessment—An Updated Industry Review

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Host cell proteins (HCP) are process‐related impurities that can co‐purify with therapeutic proteins. Some HCP impurities potentially can have an impact on patient safety (immunogenicity or toxicity), efficacy, and/or product quality. It is important to reduce the levels of HCP impurities with a well‐controlled manufacturing process and to ...
Lisette Coye, Marisa A. Jones, Georgeen Gaza‐Bulseco, Carmelata Chitikila, Severine Clavier, Delphine Fougeron, Christine Grimaldi, Karen Hurkmans, Richard Hutchinson, Brenda Kellogg, Xinrong Liu, Nisha Palackal, Mahima Tank, Pascal Valax, Thomas Waerner, Fengqiang Wang, Ying Zhang, Yiwei Zhao, Sapphire Sloan, Christina Zuch de Zafra   +19 more
wiley   +1 more source

The Nucleolus: A Central Hub for Ribosome Biogenesis and Cellular Regulatory Signals. [PDF]

Int J Mol Sci
Ponti D.
europepmc   +1 more source

Antibacterial hydrogel: The sniper of chronic wounds

BMEMat, EarlyView.
The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian, Huijun Ye, Pan Wang, Changxing Li, Xutao Guo, Ming Guan, Shilun Feng   +6 more
wiley   +1 more source

Expanded genetic and functional diversity of oceanic fungi. [PDF]

Microbiome
Peng X, Valentine DL.
europepmc   +1 more source

The Central Role of Ribosomal Proteins in p53 Regulation. [PDF]

Cancers (Basel)
Lindström MS.
europepmc   +1 more source

First report of a Plasmodium malariae SSU rRNA gene variant in Africa associated with reduced amplification by nested PCR. [PDF]

Trop Med Health
Goto M, Yamamoto K, Komaki-Yasuda K, Kano S, Ohmagari N.   +4 more
europepmc   +1 more source

P21 Ablation Unveils Strain-Specific Transcriptional Reprogramming in <i>Trypanosoma cruzi</i> Amastigotes. [PDF]

Int J Microbiol
Silveira ACA, de Souza ID, Cavalcante JVF, Teixeira TL, Orikaza CM, Dalmolin RJS, da Silveira JF, da Silva CV.   +7 more
europepmc   +1 more source

Comparative Proteomic Insights into the Immune Response of <i>Conogethes punctiferalis</i> Challenged with <i>Beauveria bassiana</i>. [PDF]

Insects
Li S, Kang Z, Li X, Wei H, Yin X, Zheng F, Liu F.   +6 more
europepmc   +1 more source