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Ribosomal protein paralogues in ribosome specialization
Philosophical Transactions of the Royal Society B: Biological SciencesRibosomes are macromolecular complexes responsible for protein synthesis, comprising ribosomal proteins (RPs) and ribosomal RNA. While most RPs are present as single copies in higher eukaryotes, a handful of them have paralogues that emerged through duplication events.
Ivan Milenkovic, Eva Maria Novoa
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2018
Wnt proteins are secreted glycoproteins that activate different intracellular signal transduction pathways. They regulate cell proliferation and are required for proper embryonic development. Misregulation of Wnt signaling can result in various diseases including cancer.
Michael Kühl, Astrid S. Pfister
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Wnt proteins are secreted glycoproteins that activate different intracellular signal transduction pathways. They regulate cell proliferation and are required for proper embryonic development. Misregulation of Wnt signaling can result in various diseases including cancer.
Michael Kühl, Astrid S. Pfister
openaire +3 more sources
Radioimmunoassay for ribosomes
Analytical Biochemistry, 1972Abstract A radioimmunoassay for quantitating ribosomes is presented. The assay allows for precise, efficient, and rapid estimation of ribosomes in small samples of tissue (50–100 mg).
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1978
Publisher Summary This chapter reviews that the normal process of translation in the ribosome is fed by energy at the expense of three chemical reactions: Ribosomecatalyzed transpeptidation, EF-Tu-mediated hydrolysis of GTP to GDP and orthophosphate, and EF-G-mediated hydrolysis of GTP.
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Publisher Summary This chapter reviews that the normal process of translation in the ribosome is fed by energy at the expense of three chemical reactions: Ribosomecatalyzed transpeptidation, EF-Tu-mediated hydrolysis of GTP to GDP and orthophosphate, and EF-G-mediated hydrolysis of GTP.
openaire +3 more sources