Results 201 to 210 of about 534,315 (335)

Novel INHAT repressor drives glioblastoma growth by promoting ribosomal DNA transcription in glioma stem cells. [PDF]

open access: yesNeuro Oncol, 2023
Tao W   +15 more
europepmc   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu   +8 more
wiley   +1 more source

Ribosomal DNA gene copies are increased in blood and brain of Japanese schizophrenia patients. [PDF]

open access: yesPLoS One, 2023
Li S   +8 more
europepmc   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

open access: yesAdvanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang   +11 more
wiley   +1 more source

Ribosomal DNA arrays are the most H-DNA rich element in the human genome. [PDF]

open access: yesNAR Genom Bioinform
Chantzi N   +6 more
europepmc   +1 more source

Editorial: Molecular organization, evolution, and function of ribosomal DNA. [PDF]

open access: yesFront Plant Sci, 2022
Volkov RA   +4 more
europepmc   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

open access: yesAdvanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song   +11 more
wiley   +1 more source

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