Results 201 to 210 of about 287,665 (235)
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The chromosomal location of ribosomal DNA in the mouse
Chromosoma, 1974In situ hybridization of I125-labelled ribosomal RNA to mouse chromosomes was used to determine the location of the rDNA loci. The results demonstrate the presence of rDNA sites on chromosomes 15, 18 and 19.
Henderson, A S+3 more
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Replicon size of yeast ribosomal DNA
Molecular and General Genetics MGG, 1984The ribosomal RNAs of the yeast Saccharomyces cerevisiae are transcribed from a 9K bp stretch of DNA which is reiterated about 120-fold in a continuous array, about 360 microns long, on chromosome XII. Although ARS activity has been detected in the repeat unit, the size and disposition of replicons along this array of identical genes has not hitherto ...
Walmsley, Richard M.+3 more
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The evolution of eukaryotic ribosomal DNA
Biosystems, 1986Mutations occur randomly throughout the ribosomal DNA (rDNA) sequence. Molecular drive (unequal crossing-over, gene conversion, and transposition) spreads these variations through the multiple copies of rDNA. Forces of selection act upon the variants to favor and fix them or disfavor and eliminate them.
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Ribosomal DNA and the Phylogeny of Frogs
Herpetological Monographs, 1993Phylogenetic analysis of 1656 aligned sites in the 28S ribosomal RNA gene of frogs supports some of the recently recognized higher groups of anurans but provides counter-support for others. The 28S rDNA data support the monophyly of the recently recognized Pipanura (me- sobatrachians plus neobatrachians), which in turn indicates paraphyly of ...
David M. Hillis+4 more
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Ribosomal DNA and Neurological Disorders
Current Molecular MedicineAbstract: Ribosomal DNA (rDNA) is important in the nucleolus and nuclear organization of human cells. Defective rDNA repeat maintenance has been reported to be closely associated with neurological disorders, such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, frontotemporal dementia, depression ...
Hong Zhou+6 more
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Ribosomal DNA instability and genome adaptability
Chromosome Research, 2019Ribosomes are large, multi-subunit ribonucleoprotein complexes, essential for protein synthesis. To meet the high cellular demand for ribosomes, all eukaryotes have numerous copies of ribosomal DNA (rDNA) genes that encode ribosomal RNA (rRNA), usually far in excess of the requirement for ribosome biogenesis.
Devika Salim+2 more
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Synthesis of ribosomal DNA in conjugating Tetrahymena
Experimental Cell Research, 1979Abstract In the ciliate protozoan Tetrahymena thermophila, a single integrated gene coding for ribosomal RNA in the micronucleus is amplified during the sexual cycle to yield many copies of extrachromosomal palindromic rDNA in the macronucleus. Hybridization of newly synthesized DNA with rRNA has shown that extensive rDNA synthesis takes place early ...
Jytte R. Nilsson+3 more
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Natural selection and ribosomal DNA in Drosophila
Genome, 1989Natural populations of Drosophila mercatorum are variable for the number of X-linked 28S ribosomal genes bearing a 5-kilobase insert. A separate polymorphic X-linked gene controls whether 28S repeats bearing the insert are preferentially underreplicated during the formation of polytene tissue.
Alan R. Templeton+3 more
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Nontranscribed spacers in Drosophila ribosomal DNA
Chromosoma, 1981Ribosomal DNA nontranscribed spacers in Drosophila virilis DNA have been examined in some detail by restriction site analysis of cloned segments of rDNA, nucleic acid hybridizations involving unfractionated rDNA, and base composition estimates. The overall G + C content of the spacer is 27--28%; this compares with 39% for rDNA as a whole, 40% for main ...
Peter M. M. Rae+2 more
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The ribosomal DNA of the Zygomycete Mucor miehei
Current Genetics, 2000The ribosomal DNA-from the Zygomycete Mucor miehei has been characterised. The complete rDNA unit was cloned by heterologous PCR using primers whose sequence matched conserved regions of the rDNA from related fungal species. The sequence of the overlapping PCR products revealed the existence of a repeated unit of 9574 bp.
Sergi Maicas, Ana C. Adam, Julio Polaina
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