Results 231 to 240 of about 534,315 (335)

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

The role of ribosomal DNA methylation in embryonic development, aging and diseases. [PDF]

Epigenetics Chromatin
Yang F, Guo X, Bao Y, Li R.
europepmc   +1 more source

Dataset of 16S ribosomal DNA sequence-based identification of endophytic bacteria isolated from healthy and diseased Sabah red algae, Kappaphycus alvarezii. [PDF]

Data Brief, 2023
Mangun VV, Sugumaran R, Lym Yong WT, Yusof NA.   +3 more
europepmc   +1 more source

Molecular Epidemiology of Japanese Isolates of Arthroderma benhamiae by Polymorphisms of Non-transcribed Spacer Region of the Ribosomal DNA.

, 2002
Takashi Mochizuki
openalex   +2 more sources

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Sir2 and Fun30 regulate ribosomal DNA replication timing via MCM helicase positioning and nucleosome occupancy. [PDF]

Elife
Lichauco C, Foss EJ, Gatbonton-Schwager T, Athow NF, Lofts B, Acob R, Taylor E, Marquez JJ, Lao U, Miles S, Bedalov A.   +10 more
europepmc   +1 more source

Aberrant DNA Methylation of Ribosomal RNA Genes in Human Cancer

, 2015
Teschler S Richter, Benedikt Linder
openalex   +1 more source

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

Advanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao, Jiahe Su, Jiawei Yuan, Qinyan Cao, Yue Wu, Yuyang Xiao, Guang Yang, Ruomu Xia, Jingpeng Yang, Yanan Li, Lina Wu, He Huang, Lingtong Meng   +12 more
wiley   +1 more source

Transcription near arrested DNA replication forks triggers ribosomal DNA copy number changes. [PDF]

Nucleic Acids Res
Sasaki M, Kobayashi T.
europepmc   +1 more source

Molecular diagnosis of visceral leishmaniasis: a French study comparing a reference PCR method targeting kinetoplast DNA and a commercial kit targeting ribosomal DNA. [PDF]

Microbiol Spectr, 2023
Pasquier G, Andreotti Q, Ravel C, Sterkers Y.   +3 more
europepmc   +1 more source