Evolution of Ribosomal Proteins [PDF]
We have studied the evolution of ribosomal proteins over a spectrum of 13 species ranging from man to plants using a two‐dimensional polyacrylamide gel electrophoresis technique. We tried to quantify the proximity of these species by coelectrophoresing the proteins from various combinations of two species.
J, Delaunay, F, Creusot, G, Schapira
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Roles of transcriptional and translational control mechanisms in regulation of ribosomal protein synthesis in Escherichia coli [PDF]
Bacterial ribosome biogenesis is tightly regulated to match nutritional conditions and to prevent formation of defective ribosomal particles. InEscherichia coli, most ribosomal protein (r-protein) synthesis is coordinated with rRNA synthesis by a ...
Burgos, Hector L +3 more
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Alterations in the ribosomal machinery in cancer and hematologic disorders
Ribosomes are essential components of the protein translation machinery and are composed of more than 80 unique large and small ribosomal proteins. Recent studies show that in addition to their roles in protein translation, ribosomal proteins are also ...
Shenoy Niraj +6 more
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Fluorescent protein tagging confirms the presence of ribosomal proteins atDrosophilapolytene chromosomes [PDF]
\ud \ud Most ribosomal proteins (RPs) are stoichiometrically incorporated into ribosomal subunits and play essential roles in ribosome biogenesis and function.
Bischof +27 more
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A newly discovered mechanism that causes the 'Minute' phenotype in fruit flies can explain how organisms are able to eliminate the mutant cells that arise occasionally during development.
Stephano Mello, Dirk Bohmann
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The Up-Regulation of Ribosomal Proteins Further Regulates Protein Expression Profile in Female Schistosoma japonicum after Pairing. [PDF]
Pairing of Schistosoma males and females leads to and maintains female sexual maturation. However, the mechanism by which pairing facilitates sexual maturation of females is not clear.
Jun Sun, Chen Li, Suwen Wang
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Different domains cooperate to target the human ribosomal L7a protein to the nucleus and to the nucleoli. [PDF]
The human ribosomal protein L7a is a component of the major ribosomal subunit. We transiently expressed in HeLa cells L7a-β-galactosidase fusion proteins and studied their subcellular localization by indirect immunofluorescence staining with anti-β ...
Giulia RUSSO +2 more
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The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both
Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim +2 more
doaj +1 more source
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire [PDF]
Idiosyncratic adverse drug reactions are unpredictable, dose independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such reactions involve
A. Lucas +47 more
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Dissecting the Nuclear Import of the Ribosomal Protein Rps2 (uS5)
The ribosome is assembled in a complex process mainly taking place in the nucleus. Consequently, newly synthesized ribosomal proteins have to travel from the cytoplasm into the nucleus, where they are incorporated into nascent ribosomal subunits. In this
Andreas Steiner +9 more
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