Eukaryotic viruses encode the ribosomal protein eL40 [PDF]
npj VirusesViruses in the phylum Nucleocytoviricota are large, complex and have an exceptionally diverse metabolic repertoire. Some encode hundreds of products involved in the translation of mRNA into protein, but none was known to encode any of the proteins in ...
Julie Thomy +4 more
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Interaction between the assembly of the ribosomal subunits: Disruption of 40S ribosomal assembly causes accumulation of extra-ribosomal 60S ribosomal protein uL18/L5. [PDF]
PLoS ONE, 2020 Inhibition of the synthesis of an essential ribosomal protein (r-protein) abrogates the assembly of its cognate subunit, while assembly of the other subunit continues.
Nusrat Rahman +2 more
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Ribosomal Protein S6: A Potential Therapeutic Target against Cancer?
International Journal of Molecular Sciences, 2021 Ribosomal protein S6 (RPS6) is a component of the 40S small ribosomal subunit and participates in the control of mRNA translation. Additionally, phospho (p)-RPS6 has been recognized as a surrogate marker for the activated PI3K/AKT/mTORC1 pathway, which ...
Y. Yi +4 more
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Roles of ribosomal proteins in hematologic disorders and cancers: a review
Emergency and Critical Care Medicine, 2023 . Ribosomes are important organelles for synthesizing proteins in cells. They are composed of ribosomal RNA and more than 80 ribosomal proteins. It is well known that an essential function of ribosomal proteins is to participate in protein translation ...
Jie Wang, Feng Yan
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Ribosomal proteins: mutant phenotypes by the numbers and associated gene expression changes [PDF]
Open Biology, 2020 Ribosomal proteins are highly conserved, many universally so among organisms. All ribosomal proteins are structural parts of the same molecular machine, the ribosome.
Michael Polymenis
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Identification of Key Genes and Pathways Involved in Circulating Tumor Cells in Colorectal Cancer
Analytical Cellular Pathology, 2022 Background. Characterization of the features associated with circulating tumor cells (CTCs) is one of major interests for predicting clinical outcome of colorectal cancer (CRC) patients.
Ruijun Pan +7 more
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mSystems, 2023 Many mutations in genes for ribosomal proteins (r-proteins) and assembly factors cause cell stress and altered cell fate, resulting in congenital diseases collectively called ribosomopathies.
Md Shamsuzzaman +6 more
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Intron dynamics in ribosomal protein genes. [PDF]
PLoS ONE, 2007 The role of spliceosomal introns in eukaryotic genomes remains obscure. A large scale analysis of intron presence/absence patterns in many gene families and species is a necessary step to clarify the role of these introns.
Maki Yoshihama +2 more
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Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
Science, 2020 Metastasis: A matter of translation? Solid tumors shed a small number of cancer cells into the bloodstream, some of which are believed to contribute to metastasis.
R. Ebright +24 more
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Evolution of ribosomal protein network architectures
Scientific Reports, 2021 To perform an accurate protein synthesis, ribosomes accomplish complex tasks involving the long-range communication between its functional centres such as the peptidyl transfer centre, the tRNA bindings sites and the peptide exit tunnel.
Youri Timsit +2 more
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