Results 121 to 130 of about 6,159,973 (405)

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Survey and multigene characterization of stolbur phytoplasmas on various plant species in Serbia

open access: yesPhytopathologia Mediterranea, 2013
Stolbur phytoplasmas were detected in 116 out of more than 200 samples from nine plant species col- lected in 2009‒2010 in Serbia. Phytoplasmas were detected and identified by restriction fragment length polymor- phism (RFLP) analysis of polymerase chain
Jelena MITROVIĆ   +2 more
doaj   +1 more source

Ribosomal protein L32 enhances hepatocellular carcinoma progression

open access: yesCancer Medicine, 2023
Purpose The underlying mechanisms of hepatocellular carcinoma (HCC) have not been fully investigated, and effective biomarkers for HCC are still needed to be explored.
Guoxin Hou   +3 more
doaj   +1 more source

Ribosome recycling induces optimal translation rate at low ribosomal availability [PDF]

open access: yes, 2014
Funding statement The authors thank BBSRC (BB/F00513/X1, BB/I020926/1 and DTG) and SULSA for funding. Acknowledgement The authors thank R. Allen, L. Ciandrini, B. Gorgoni and P.
Alberts B   +3 more
core   +1 more source

The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog, Rpl22l1

open access: yesPLoS Genetics, 2013
Most yeast ribosomal protein genes are duplicated and their characterization has led to hypotheses regarding the existence of specialized ribosomes with different subunit composition or specifically-tailored functions.
Monique N. O’Leary   +19 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

A genomic approach to the study of Tribolium castaneum genetics, development & evolution [PDF]

open access: yes, 2004
During the last decade, Tribolium castaneum has become the insect of choice for comparative genetics and developmental studies outside of drosophilids. Until recently, most molecular studies have focused on the comparative analysis of early development ...
Savard, Joël
core  

Most RNAs regulating ribosomal protein biosynthesis in Escherichia coli are narrowly distributed to Gammaproteobacteria

open access: yesNucleic Acids Research, 2013
In Escherichia coli, 12 distinct RNA structures within the transcripts encoding ribosomal proteins interact with specific ribosomal proteins to allow autogenous regulation of expression from large multi-gene operons, thus coordinating ribosomal protein ...
Yang Fu   +3 more
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

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