Results 131 to 140 of about 6,082,749 (396)

Compound Heterozygous MRPS14 Variants Associated With Leigh Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT MRPS14 (uS14m) is a nuclear‐encoded ribosomal protein important for mitochondria‐specific translation. To date, only a single individual with a recessive MRPS14‐related disorder (also known as COXPD38) has been reported. We report an additional subject possessing novel compound heterozygous MRPS14 variants (p.Asp37Asn, p.Asn60Asp). The subject
Maria Gabriela Otero, Christina Freeman, Ruchi Shah, Renkui Bai, Hong Cui, Marian Castro, Zachary Myers, Eric Choy, Derek Chan, Molly Easter, Sophia Y. Zhao, Madeline Babros, Ruchi Garg, Matthew Deardorff, Franklin Moser, Tyler Mark Pierson   +15 more
wiley   +1 more source

Combining multiomics to analyze the molecular mechanism of hair follicle cycle change in cashmere goats from Inner Mongolia

Frontiers in Veterinary Science
Sheep body size can directly reflect the growth rates and fattening rates of sheep and is also an important index for measuring the growth performance of meat sheep.Inner Mongolia Cashmere Goat is a local excellent breed of cashmere and meat dual-purpose,
Chongyan Zhang, Chongyan Zhang, Qing Qin, Qing Qin, Zhichen Liu, Zhichen Liu, Yichuan Wang, Yichuan Wang, Mingxi Lan, Mingxi Lan, Dan Zhao, Dan Zhao, Jingwen Zhang, Jingwen Zhang, Zhixin Wang, Zhixin Wang, Jinquan Li, Jinquan Li, Jinquan Li, Zhihong Liu, Zhihong Liu, Zhihong Liu, Zhihong Liu   +22 more
doaj   +1 more source

The architecture of mammalian ribosomal protein promoters

BMC Evolutionary Biology, 2005
Background Mammalian ribosomes contain 79 different proteins encoded by widely scattered single copy genes. Coordinate expression of these genes at transcriptional and post-transcriptional levels is required to ensure a roughly equimolar accumulation of ...
Perry Robert P
doaj   +1 more source

Regulation of the HDM2-p53 pathway by ribosomal protein L6 in response to ribosomal stress

Nucleic Acids Research, 2013
The HDM2-p53 loop is crucial for monitoring p53 level and human pathologies. Therefore, identification of novel molecules involved in this regulatory loop is necessary for understanding the dynamic regulation of p53 and treatment of human diseases. Here,
Dongmei Bai, Jinfang Zhang, Weichun Xiao, Xiaofeng Zheng   +3 more
semanticscholar   +1 more source

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

ACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi, Ennio Giulio Favalli, Gabriella Maioli, Elena Agape, Marzia Rossato, Matteo Paini, Adriana Severino, Barbara Vigone, Martina Biggioggero, Elena Trombetta, Roberto Caporali, Lorenzo Beretta   +11 more
wiley   +1 more source

Anopheles stephensi p38 MAPK signaling regulates innate immunity and bioenergetics during Plasmodium falciparum infection. [PDF]

, 2015
BackgroundFruit flies and mammals protect themselves against infection by mounting immune and metabolic responses that must be balanced against the metabolic needs of the pathogens.
Aguirre, Alejandro, Cheung, Kong, Drexler, Anna, Eigenheer, Richard, Giulivi, Cecilia, Glennon, Elizabeth KK, Klyver, John M, Lewis, Edwin E, Luckhart, Shirley, Napoli, Eleonora, Pakpour, Nazzy, Phinney, Brett S, Surachetpong, Win, Wang, Bo   +13 more
core   +1 more source

Ribosomal Protein S6, a Target of Rapamycin, Is Involved in the Regulation of rRNA Genes by Possible Epigenetic Changes in Arabidopsis *

Journal of Biological Chemistry, 2013
Background: Ribosomal protein S6 has been known to be a key downstream effector of the TOR signaling pathway. Results: We demonstrated that ribosomal protein interacts with a histone deacetylase and binds to rRNA gene promoter.
Y. Kim, Sunghan Kim, Yun-jeong Shin, Y. Hur, Woo-Young Kim, M. Lee, C. Cheon, D. Verma   +7 more
semanticscholar   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Expresión diferencial de genes en Pyropia columbina (Bangiales, Rhodophyta) bajo hidratación y desecación natural [PDF]

, 2013
Indexación: Web of Science; Scielo.RESUMEN. En Zonas Costeras rocosas, la desecación es gatillada porción Cambios Diarios en los Niveles de marea, y la Evidencia indica experimental de Me Distribución de las algas en la zona intermareal no está ...
Contreras-Porcia, Loretto, Correa, Juan A., Fierro, Camila, Flores-Molina, María Rosa, Guajardo, Eduardo, Kube, Michael, Lovazzano, Carlos, López-Cristoffanini, Camilo, Núñez, Alejandra, Reinhardt, Richard, Thomas, Daniela   +10 more
core  

Protein folding on the ribosome studied using NMR spectroscopy [PDF]

, 2013
NMR spectroscopy is a powerful tool for the investigation of protein folding and misfolding, providing a characterization of molecular structure, dynamics and exchange processes, across a very wide range of timescales and with near atomic resolution.
Agrawal, Agrawal, Amero, Anfinsen, Augustyniak, Augustyniak, Balbach, Ban, Baram, Bhushan, Bhushan, Bhushan, Blanco, Bocharov, Bouvignies, Buevich, Bushuev, Cabrita, Cabrita, Cai, Callaghan, Cavagnero, Cavalli, Chiti, Chow, Christodoulou, Christopher A. Waudby, Clark, Clark, Corazza, Cowgill, Crooke, De Prat Gay, De Prat Gay, de Swiet, Dempsey, Deuerling, Diaconu, Didenko, Dinner, Dobson, Dobson, Dror, Eichmann, Elcock, Eletsky, Ellis, Englander, Ernst, Evans, Farjon, Favier, Fedorov, Fedorov, Fedyukina, Fedyunin, Ferbitz, Ferrage, Fersht, Fersht, Fersht, Fucini, Fucini, Gabashvili, Genevaux, Gershenson, Gilbert, Go, Gudkov, Guo, Han, Hautbergue, Helgstrand, Hiller, Hoch, Hoffmann, Hoffmann, Hoffmann, Hsu, Hsu, Hsu, Hsu, Hyberts, Hyberts, Hyberts, Hyeon, Hélène Launay, Ito, Jansens, John Christodoulou, Kaiser, Kaiser, Katranidis, Kelkar, Kelly, Khushoo, Kimchi-Sarfaty, Kleizen, Klepeis, Komar, Koppel, Korzhnev, Kovacs, Kramer, Kumar, Lakshmipathy, Lavalette, Lescop, Lescop, Levinthal, Li, Li, Lill, Lindorff-Larsen, Lisa D. Cabrita, Loksztejn, Lu, Lucas, Ludlam, Maier, Maldonado, Mallam, Mallam, Martinez-Hackert, Martínez, Matsuura, McCoy, Montesano-Roditis, Mulder, Nakatogawa, Neira, Neira, Neudecker, Neudecker, Nicola, Nissen, Ollerenshaw, Olson, O’Brien, O’Brien, O’Brien, Patzelt, Pervushin, Pervushin, Pervushin, Piana, Potestio, Prentiss, Price, Price, Rajagopalan, Rajagopalan, Raman, Rennella, Riek, Riek, Riek, Robosky, Robustelli, Rovnyak, Rovnyak, Ruschak, Rutkowska, Rutkowska, Salvatella, Schaffitzel, Schanda, Schanda, Schanda, Schmeing, Scholz, Schuwirth, Seidelt, Selenko, Selmer, Serber, Shaw, Shen, Shen, Shimizu, Sprangers, Stejskal, Sułkowska, Tenson, Teter, Theillet, Tritton, Tsalkova, Tugarinov, Ulrich, Vallurupalli, Vendruscolo, Verdier, Virnau, Voehler, Vogtherr, Voss, Waudby, Waudby, Whitford, Wilkins, Wilson, Woolhead, Yao, Zhang, Zhang   +205 more
core   +1 more source