Results 11 to 20 of about 6,082,749 (396)
Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]
International Journal of Molecular Sciences, 2021 Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis.
Annalisa Pecoraro +3 more
semanticscholar +4 more sources
The role of ribosomal protein networks in ribosome dynamics. [PDF]
Nucleic Acids ResAbstract Accurate protein synthesis requires ribosomes to integrate signals from distant functional sites and execute complex dynamics. Despite advances in understanding ribosome structure and function, two key questions remain: how information is transmitted between these distant sites, and how ribosomal movements are synchronized?
Timsit Y +2 more
europepmc +3 more sources
Ribosomal proteins: functions beyond the ribosome [PDF]
Journal of Molecular Cell Biology, 2015 Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition,
Peng Liao +4 more
openaire +3 more sources
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
Science, 2020 Metastasis: A matter of translation? Solid tumors shed a small number of cancer cells into the bloodstream, some of which are believed to contribute to metastasis.
R. Ebright +24 more
semanticscholar +1 more source
PLoS ONE, 2022 Cancer cachexia is accompanied by muscle atrophy, sharing multiple common catabolic pathways with sarcopenia, including mitochondrial dysfunction. This study investigated gene expression from skeletal muscle tissues of older healthy adults, who are at ...
Konstantinos Prokopidis +4 more
doaj +1 more source
The characteristic analysis of ribosomal protein l12 in haemaphysalis longicornis (acari: ixodidae) ticks [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2022 Ribosomal protein L12 (RpL12) plays an important role in ovarian development and engorgement in vertebrates and invertebrates. However, the functional characteristics of RpL12 in ticks are not clear.
Jin LUO +6 more
doaj +1 more source
Regulation of ribosomal protein genes: An ordered anarchy
Wiley Interdisciplinary Reviews - RNA, 2020 Ribosomal protein genes are among the most highly expressed genes in most cell types. Their products are generally essential for ribosome synthesis, which is the cornerstone for cell growth and proliferation.
Cyrielle Petibon +3 more
semanticscholar +1 more source
Evolution of Ribosomal Proteins [PDF]
European Journal of Biochemistry, 1973 We have studied the evolution of ribosomal proteins over a spectrum of 13 species ranging from man to plants using a two‐dimensional polyacrylamide gel electrophoresis technique. We tried to quantify the proximity of these species by coelectrophoresing the proteins from various combinations of two species.
Francine Creusot +2 more
openaire +4 more sources
Intron dynamics in ribosomal protein genes. [PDF]
PLoS ONE, 2007 The role of spliceosomal introns in eukaryotic genomes remains obscure. A large scale analysis of intron presence/absence patterns in many gene families and species is a necessary step to clarify the role of these introns.
Maki Yoshihama +2 more
doaj +1 more source
Cotranslational Folding of Proteins on the Ribosome [PDF]
Biomolecules, 2020 Many proteins in the cell fold cotranslationally within the restricted space of the polypeptide exit tunnel or at the surface of the ribosome. A growing body of evidence suggests that the ribosome can alter the folding trajectory in many different ways. In this review, we summarize the recent examples of how translation affects folding of single-domain,
Marija Liutkute +2 more
openaire +4 more sources