Results 11 to 20 of about 6,159,973 (405)
Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]
International Journal of Molecular Sciences, 2021 Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis.
Annalisa Pecoraro +3 more
semanticscholar +4 more sources
The role of ribosomal protein networks in ribosome dynamics. [PDF]
Nucleic Acids ResAbstract Accurate protein synthesis requires ribosomes to integrate signals from distant functional sites and execute complex dynamics. Despite advances in understanding ribosome structure and function, two key questions remain: how information is transmitted between these distant sites, and how ribosomal movements are synchronized?
Timsit Y +2 more
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Ribosomal proteins: functions beyond the ribosome [PDF]
Journal of Molecular Cell Biology, 2015 Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition,
Peng Liao +4 more
openaire +3 more sources
Evolution of ribosomal protein network architectures
Scientific Reports, 2021 To perform an accurate protein synthesis, ribosomes accomplish complex tasks involving the long-range communication between its functional centres such as the peptidyl transfer centre, the tRNA bindings sites and the peptide exit tunnel.
Youri Timsit +2 more
doaj +1 more source
Regulation of ribosomal protein genes: An ordered anarchy
Wiley Interdisciplinary Reviews - RNA, 2020 Ribosomal protein genes are among the most highly expressed genes in most cell types. Their products are generally essential for ribosome synthesis, which is the cornerstone for cell growth and proliferation.
Cyrielle Petibon +3 more
semanticscholar +1 more source
Evolution of Ribosomal Proteins [PDF]
European Journal of Biochemistry, 1973 We have studied the evolution of ribosomal proteins over a spectrum of 13 species ranging from man to plants using a two‐dimensional polyacrylamide gel electrophoresis technique. We tried to quantify the proximity of these species by coelectrophoresing the proteins from various combinations of two species.
Francine Creusot +2 more
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Non‐ribosomal insights into ribosomal P2 protein in Plasmodium falciparum‐infected erythrocytes
MicrobiologyOpen, 2021 The enormous complexity of the eukaryotic ribosome has been a real challenge in unlocking the mechanistic aspects of its amazing molecular function during mRNA translation and many non‐canonical activities of ribosomal proteins in eukaryotic cells. While
Sudipta Das +2 more
doaj +1 more source
The characteristic analysis of ribosomal protein l12 in haemaphysalis longicornis (acari: ixodidae) ticks [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2022 Ribosomal protein L12 (RpL12) plays an important role in ovarian development and engorgement in vertebrates and invertebrates. However, the functional characteristics of RpL12 in ticks are not clear.
Jin LUO +6 more
doaj +1 more source
Cotranslational Folding of Proteins on the Ribosome [PDF]
Biomolecules, 2020 Many proteins in the cell fold cotranslationally within the restricted space of the polypeptide exit tunnel or at the surface of the ribosome. A growing body of evidence suggests that the ribosome can alter the folding trajectory in many different ways. In this review, we summarize the recent examples of how translation affects folding of single-domain,
Marija Liutkute +2 more
openaire +4 more sources
Definitions, 2020 Proteins present within the ribosomal subunits. In eukaryotes there are 50 proteins in the large subunit and 33 in the small subunit.
semanticscholar +1 more source