The C-terminal tail of ribosomal protein Rps15 is engaged in cytoplasmic pre-40S maturation
RNA Biology, 2022 The small ribosomal subunit protein Rps15/uS19 is involved in early nucleolar ribosome biogenesis and subsequent nuclear export of pre-40S particles to the cytoplasm.
Ingrid Rössler +7 more
doaj +1 more source
A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome [PDF]
, 2013 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Dunker, A. Keith +6 more
core +2 more sources
Tumor Biology, 2017 Hepatocellular carcinoma is one of the most prevalent neoplasms and the leading cause of cancer-related mortality worldwide. Mitochondrial ribosomal protein S23 is encoded by a nuclear gene and participates in mitochondrial protein translation ...
Meng Pu +9 more
doaj +1 more source
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35
Nature Communications, 2019 The majority of patients with neuroblastoma due to MYCN oncogene amplification and consequent N-Myc oncoprotein over-expression die of the disease. Here our analyses of RNA sequencing data identify the long noncoding RNA lncNB1 as one of the transcripts ...
Pei Y. Liu +34 more
semanticscholar +1 more source
cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]
, 2008 mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA +5 more
core +1 more source
Roles of transcriptional and translational control mechanisms in regulation of ribosomal protein synthesis in Escherichia coli [PDF]
, 2017 Bacterial ribosome biogenesis is tightly regulated to match nutritional conditions and to prevent formation of defective ribosomal particles. InEscherichia coli, most ribosomal protein (r-protein) synthesis is coordinated with rRNA synthesis by a ...
Burgos, Hector L +3 more
core +3 more sources
The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types
OncoTarget, 2017 For many years, defects in the ribosome have been associated to cancer. Recently, somatic mutations and deletions affecting ribosomal protein genes were identified in a few leukemias and solid tumor types.
L. Fancello +4 more
semanticscholar +1 more source
The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both
Biomarker Research, 2021 Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim +2 more
doaj +1 more source
Mitochondrial ribosome assembly in Neurospora. Structural analysis of mature and partially assembled ribosomal subunits by equilibrium centrifugation in CsCl gradients [PDF]
, 1982 In Neurospora, one protein associated with the mitochondrial small ribosomal subunit (S-5, Mr 52,000) is synthesized intramitochondrially and is assumed to be encoded by mtDNA.
Lambowitz, Alan M., LaPolla, Robert J.
core +1 more source
Role of ribosomal protein mutations in tumor development (Review)
International Journal of Oncology, 2016 Ribosomes are cellular machines essential for protein synthesis. The biogenesis of ribosomes is a highly complex and energy consuming process that initiates in the nucleolus.
Kaveh M. Goudarzi, M. Lindström
semanticscholar +1 more source