Results 31 to 40 of about 540,233 (304)

Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia

open access: yesHaematologica, 2014
Diamond-Blackfan anemia is a congenital erythroid hypoplasia caused by functional haploinsufficiency of genes encoding ribosomal proteins. Mutations involving the ribosomal protein S19 gene are detected in 25% of patients.
Pekka Jaako   +7 more
doaj   +1 more source

Isolation of Ribosomal Particles from the Unicellular Cyanobacterium Synechocystis sp. PCC 6803 [PDF]

open access: yes, 2017
Isolation of ribosomal particles is an essential step in the study of ribosomal components as well as in the analysis of trans-acting factors that interact with the ribosome to regulate protein synthesis and modulate the expression profile of the cell ...
Galmozzi, Carla V.   +1 more
core   +1 more source

High MRPS23 expression contributes to hepatocellular carcinoma proliferation and indicates poor survival outcomes

open access: yesTumor Biology, 2017
Hepatocellular carcinoma is one of the most prevalent neoplasms and the leading cause of cancer-related mortality worldwide. Mitochondrial ribosomal protein S23 is encoded by a nuclear gene and participates in mitochondrial protein translation ...
Meng Pu   +9 more
doaj   +1 more source

The C-terminal tail of ribosomal protein Rps15 is engaged in cytoplasmic pre-40S maturation

open access: yesRNA Biology, 2022
The small ribosomal subunit protein Rps15/uS19 is involved in early nucleolar ribosome biogenesis and subsequent nuclear export of pre-40S particles to the cytoplasm.
Ingrid Rössler   +7 more
doaj   +1 more source

A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome [PDF]

open access: yes, 2013
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Dunker, A. Keith   +6 more
core   +2 more sources

Bacterial protein interaction networks: connectivity is ruled by gene conservation, essentiality and function [PDF]

open access: yes, 2020
Protein-protein interaction (PPI) networks are the backbone of all processes in living cells. In this work we relate conservation, essentiality and functional repertoire of a gene to the connectivity $k$ of the corresponding protein in the PPI networks ...
Cimini, Giulio   +2 more
core   +2 more sources

Ribosomal Proteins [PDF]

open access: yesEuropean Journal of Biochemistry, 1971
50 S ribosomal subunits of Escherichia coli obtained by zonal centrifugation in B XV rotors were treated with various concentrations of LiCl in the absence and presence of urea. This treatment resulted in three protein fractions, each of which was subjected to CM‐cellulose chromatography. Gel filtration in Sephadex G‐100 (and preparative polyacrylamide
I, Hindennach   +2 more
openaire   +4 more sources

Ribosomal Proteins in Ribosome Assembly

open access: yesBiomolecules
Ribosomes are the cellular machinery responsible for translating mRNA into proteins, a process fundamental to all domains of life from bacteria to eukaryotes [...]
Brigitte Pertschy, Ingrid Zierler
openaire   +4 more sources

cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]

open access: yes, 2008
mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA   +5 more
core   +1 more source

Mitochondrial ribosome assembly in Neurospora. Structural analysis of mature and partially assembled ribosomal subunits by equilibrium centrifugation in CsCl gradients [PDF]

open access: yes, 1982
In Neurospora, one protein associated with the mitochondrial small ribosomal subunit (S-5, Mr 52,000) is synthesized intramitochondrially and is assumed to be encoded by mtDNA.
Lambowitz, Alan M., LaPolla, Robert J.
core   +1 more source

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