Results 51 to 60 of about 6,082,749 (396)

The Evolution of the Ribosomal Protein-MDM2-p53 Pathway.

Cold Spring Harbor Perspectives in Medicine, 2016
The progression of our understanding of ribosomal proteins as static building blocks of the ribosome to highly integrated sensors of p53 surveillance and function has achieved a tremendous rate of growth over the past several decades. As the workhorse of
C. Deisenroth, D. Franklin, Yanping Zhang   +2 more
semanticscholar   +1 more source

cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]

, 2008
mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA, C. Cirulli, PIETROPAOLO, CONCETTA, PUCCI, PIETRO, RUSSO, ANNAPINA, RUSSO, GIULIA   +5 more
core   +1 more source

The Arabidopsis TOR Kinase Specifically Regulates the Expression of Nuclear Genes Coding for Plastidic Ribosomal Proteins and the Phosphorylation of the Cytosolic Ribosomal Protein S6

Frontiers in Plant Science, 2016
Protein translation is an energy consuming process that has to be fine-tuned at both the cell and organism levels to match the availability of resources.
Thomas Dobrenel, E. Mancera-Martínez, Céline Forzani, Marianne Azzopardi, Marlène Davanture, Manon Moreau, Mikhail Schepetilnikov, Johana Chicher, O. Langella, M. Zivy, C. Robaglia, L. Ryabova, J. Hanson, C. Meyer   +13 more
semanticscholar   +1 more source

Roles of transcriptional and translational control mechanisms in regulation of ribosomal protein synthesis in Escherichia coli [PDF]

, 2017
Bacterial ribosome biogenesis is tightly regulated to match nutritional conditions and to prevent formation of defective ribosomal particles. InEscherichia coli, most ribosomal protein (r-protein) synthesis is coordinated with rRNA synthesis by a ...
Burgos, Hector L, Gourse, Richard L, O\u27Connor, Kevin, Sanchez-Vazquez, Patricia   +3 more
core   +3 more sources

Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation

Nature Communications, 2016
Eukaryotic ribosomes assemble by association of ribosomal RNA with ribosomal proteins into nuclear precursor particles, which undergo a complex maturation pathway coordinated by non-ribosomal assembly factors.
Valentin Mitterer, Guillaume Murat, S. Réty, Magali Blaud, L. Delbos, T. Stanborough, H. Bergler, N. Leulliot, D. Kressler, Brigitte Pertschy   +9 more
semanticscholar   +1 more source

Fluorescent protein tagging confirms the presence of ribosomal proteins atDrosophilapolytene chromosomes [PDF]

, 2013
\ud \ud Most ribosomal proteins (RPs) are stoichiometrically incorporated into ribosomal subunits and play essential roles in ribosome biogenesis and function.
Bischof, Bohnsack, Brogna, Coleno-Costes, Dai, Dai, De, De, Freeman, Gavin, Gerlitz, Hurt, Inada, Johansen, Jurica, Klinge, Kondrashov, Lam, Lee, Malygin, Marygold, Ni, Ramanathan, Shi, Shopland, Steitz, Warner, Zhimulev   +27 more
core   +3 more sources

Introns regulate the production of ribosomal proteins by modulating splicing of duplicated ribosomal protein genes

Nucleic Acids Research, 2016
Most budding yeast introns exist in the many duplicated ribosomal protein genes (RPGs) and it has been posited that they remain there to modulate the expression of RPGs and cell growth in response to stress.
Cyrielle Petibon, J. Parenteau, Mathieu Catala, Sherif Abou Elela   +3 more
semanticscholar   +1 more source

pS6K1 as an efficacy marker of GnRH agonist with premenopausal breast cancer

Endocrine Connections, 2019
Estradiol is a key factor for tumorigenesis and prognosis of hormone receptor-positive breast cancer. Adipocytes are one source of estradiol in patients with breast cancer. Recent studies have shown that phosphorylated ribosomal protein S6 kinase-1 plays
Chan Sub Park, Jihye Choi, Min-Ki Seong, Sung-Eun Hong, Jae-Sung Kim, In-Chul Park, Hyesil Seol, Woo Chul Noh, Hyun-Ah Kim   +8 more
doaj   +1 more source

Quantitative Proteomic Analysis of Plasma Exosomes to Identify the Candidate Biomarker of Imatinib Resistance in Chronic Myeloid Leukemia Patients

Frontiers in Oncology, 2021
BackgroundImatinib (IM), a tyrosine kinase inhibitor (TKI), has markedly improved the survival and life quality of chronic myeloid leukemia (CML) patients.
Mei-Yong Li, Cui Zhao, Cui Zhao, Lian Chen, Fang-Yi Yao, Fang-Min Zhong, Ying Chen, Shuai Xu, Jun-Yao Jiang, Yu-Lin Yang, Qing-Hua Min, Jin Lin, Hai-Bin Zhang, Jing Liu, Xiao-Zhong Wang, Bo Huang   +15 more
doaj   +1 more source

Ribosomal trafficking is reduced in Schwann cells following induction of myelination. [PDF]

, 2015
Local synthesis of proteins within the Schwann cell periphery is extremely important for efficient process extension and myelination, when cells undergo dramatic changes in polarity and geometry.
Love, James M, Shah, Sameer B
core   +2 more sources