Results 131 to 140 of about 5,783,905 (321)

Lactobacillus johnsonii Generates Cyclo(pro‐trp) and Promotes Intestinal Ca2+ Absorption to Alleviate CKD–SHPT

open access: yesAdvanced Science, EarlyView.
The mechanism map of how L.johnsonii generates cyclo(pro‐trp) to alleviate CKD–SHPT by promoting the expression of CaSR and TRPV4 in IECs, enhancing Ca2+ absorption, and negatively feedback inhibiting iPTH secretion. Abstract Patients with chronic kidney disease (CKD) are at a high risk of developing secondary hyperparathyroidism (SHPT), which may ...
Xiong Zeng   +13 more
wiley   +1 more source

Posttranslational Modifications of Ribosomal Proteins in Escherichia coli

open access: yesActa Naturae, 2011
А number of ribosomal proteins inEscherichia coliundergo posttranslational modifications. Six ribosomal proteins are methylated (S11, L3, L11, L7/L12, L16, and L33), three proteins are acetylated (S5, S18, and L7), and protein S12 is methylthiolated ...
M. Nesterchuk   +2 more
semanticscholar   +1 more source

Dimethyl Itaconate Alleviates Escherichia coli‐Induced Endometritis Through the Guanosine‐CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae

open access: yesAdvanced Science, EarlyView.
The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He   +6 more
wiley   +1 more source

Computer simulations of the bacterial ribosome using a general purpose coarse-grained model MARTINI [PDF]

open access: yesarXiv
Ribosomes are critical biomolecular nanomachines responsible for protein synthesis in all known organisms. The function and dynamics of ribosomes can be studied using molecular dynamics computer simulations. Although this task remains challenging at atomic level, several studies have reported all-atom molecular dynamics simulations of the entire ...
arxiv  

Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3

open access: yesAdvanced Science, EarlyView.
MFN1 exerts its function partially through histone H3.3 in early embryos. MFN1 colocalizes with PADI6, and its deficiency results in compromised cytoplasmic lattices and ribosomal subunits, leading to declined H3.3 protein level. This, in turn, hinders the incorporation of H3.3 into the embryonic genome, thereby causing failure of male pronucleus ...
Xiao‐yan Shi   +9 more
wiley   +1 more source

Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation

open access: yesNature Communications, 2016
Ribosome biogenesis involves the hierarchical assembly of several proteins and RNA components. Here the authors describe a mechanism for ribosomal protein S3 incorporation into 40S ribosomal subunits that involves S3 dimerization and stepwise ...
Valentin Mitterer   +9 more
doaj   +1 more source

A stochastic model of the production of multiple proteins in cells [PDF]

open access: yesarXiv, 2014
The production processes of proteins in prokaryotic cells are investigated. Most of the mathematical models in the literature study the production of {\em one} fixed type of proteins. When several classes of proteins are considered, an important additional aspect has to be taken into account, the limited common resources of the cell (polymerases and ...
arxiv  

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