Results 201 to 210 of about 5,897,691 (228)

Ribosomal Proteins Control Tumor Suppressor Pathways in Response to Nucleolar Stress

Bioessays, 2019
Ribosome biogenesis includes the making and processing of ribosomal RNAs, the biosynthesis of ribosomal proteins from their mRNAs in the cytosol and their transport to the nucleolus to assemble pre-ribosomal particles. Several stresses including cellular
Frédéric Lessard, L. Brakier-Gingras, G. Ferbeyre   +2 more
semanticscholar   +1 more source

Ribosomal Proteins in the Spotlight

Critical Reviews in Biochemistry and Molecular Biology, 2005
The assignment of specific ribosomal functions to individual ribosomal proteins is difficult due to the enormous cooperativity of the ribosome; however, important roles for distinct ribosomal proteins are becoming evident. Although rRNA has a major role in certain aspects of ribosomal function, such as decoding and peptidyl-transferase activity ...
Daniel N. Wilson, Knud H. Nierhaus
openaire   +3 more sources

The roles of moonlight ribosomal proteins in the development of human cancers

Journal of Cellular Physiology, 2018
“Moonlighting protein” is a term used to define a single protein with multiple functions and different activities that are not derived from gene fusions, multiple RNA splicing, or the proteolytic activity of promiscuous enzymes.
Ghader Molavi, N. Samadi, Elaheh Zadeh Hosseingholi   +2 more
semanticscholar   +1 more source

Protein folding on the ribosome

Current Opinion in Structural Biology, 2010
In living systems, polypeptide chains are synthesised on ribosomes, molecular machines composed of over 50 protein and nucleic acid molecules. As nascent chains emerge from the ribosomal exit tunnel and into the cellular environment, the majority must fold into specific structures in order to function.
Lisa D. Cabrita, John Christodoulou, Christopher M. Dobson   +2 more
openaire   +3 more sources

Ribosomal proteins in halobacteria

Canadian Journal of Microbiology, 1989
The amino acid sequences of 16 ribosomal proteins from archaebacterium Halobacterium marismortui have been determined by a direct protein chemical method. In addition, amino acid sequences of three proteins, S11, S18, and L25, have been established by DNA sequencing of their genes as well as by protein sequencing.
M, Kimura, E, Arndt, T, Hatakeyama, T, Hatakeyama, J, Kimura   +4 more
openaire   +3 more sources

Ribosome-inactivating proteins

Toxicon, 1997
Abstract Ribosome-inactivating proteins (RIPs, review by Barbieri et a/. 1993) are a class of proteins present in various tissues of several plants which inactivate mammalian ribosomes and, with less activity and to variable extent, plant, fungal, and bacterial ribosomes. They are enzymes, N-glycosidases, which release adenine from rRNA.
openaire   +4 more sources

Ribosomal RNA: the message or matrix for ribosomal proteins

Canadian Journal of Biochemistry, 1976
The known nucleotide sequence of Escherichia coli 16S ribosomal RNA has been converted to amino acid sequences in all possible ways, and compared to known ribosomal protein sequences. The degree of similarity is precisely what one would expect by chance alone, providing additional evidence that ribosomal proteins cannot be coded for by ribosomal RNA.
A. T. Matheson, L. P. Visentin, D. R. Miller   +2 more
openaire   +3 more sources

The role of ribosomal protein for the binding of dihydrostreptomycin to ribosomes

Biochemical and Biophysical Research Communications, 1968
Abstract Although the lethal action of streptomycin (SM) may not be related to its effect on the protein biosynthesis, it appears clear that SM influences ribosomal function through inhibition or miscoding ( Davies et al. , 1964 ). The target of SM action is apparently 30S ribosomal subunits ( Cox et al. , 1962 ).
Yoriko Tanaka, Hideko Kaji
openaire   +3 more sources

Ribosomal protein paralogues in ribosome specialization

Philosophical Transactions of the Royal Society B: Biological Sciences
Ribosomes are macromolecular complexes responsible for protein synthesis, comprising ribosomal proteins (RPs) and ribosomal RNA. While most RPs are present as single copies in higher eukaryotes, a handful of them have paralogues that emerged through duplication events.
Ivan Milenkovic, Eva Maria Novoa
openaire   +2 more sources

The synthesis of ribosomal protein

Journal of Theoretical Biology, 1965
Abstract The hypothesis that nascent R-RNA associated with neosomes forms the unit responsible for the synthesis of ribosomal protein leads to a number of self-consistent relationships. The RNA of a 70 s ribosome is long enough to act as template for six molecules of ribosomal protein.
openaire   +3 more sources