Results 181 to 190 of about 441,887 (290)

RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Lee H   +13 more
europepmc   +1 more source

Alternative Translation Initiation in PRKN Delays the Onset of Parkinson's Disease and Offers a Therapeutic Target

open access: yesAnnals of Neurology, EarlyView.
Objective Biallelic variants in PRKN cause autosomal recessive Parkinson's disease (PD) with a median age at onset of 31 years. When evaluating the 16 previously published carriers of a homozygous deletion of Exon 2 from the International Parkinson's Disease and Movement Disorder Society Gene Database (MDSGene) database, the median age at onset is ...
Arian Hach   +14 more
wiley   +1 more source

RaPID Selection of Backbone Macrocyclic Peptides Targeting Akt2

open access: yesAngewandte Chemie, EarlyView.
Backbone macrocyclic peptide library (BMP) library was screened against Akt2 via RaPID to discover potent BMPPakti‐3 (IC50 = 34 nM). ABSTRACT Backbone‐cyclic peptides (BMPs) are an attractive class of molecules appeared in diverse natural bioactive products. However, mRNA display technology coupled with ribosomal synthesis is intrinsically inapplicable
Koki Shinbara   +4 more
wiley   +2 more sources

Ribozyme für die RNA‐katalysierte Methylierung und Markierung von RNA

open access: yesAngewandte Chemie, EarlyView.
Ribozyme sind vielseitige Werkzeuge für die präzise Modifikation von RNA. Das Reaktionsspektrum in‐vitro‐selektierter Ribozyme reicht vom Einbau funktioneller Gruppen und Fluorophoren bis zu natürlichen RNA‐Methylierungen. Dieser Übersichtsartikel präsentiert Cofaktor‐abhängige Ribozyme für die positionsgenaue Markierung und Modifikation von RNA ...
Carolin P. M. Scheitl   +1 more
wiley   +1 more source

Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome. [PDF]

open access: yesElife
Nielsen T   +20 more
europepmc   +1 more source

Chemoproteomics unveils Sofalcone targeting ribosomal proteins to inhibit protein synthesis in Staphylococcus aureus. [PDF]

open access: yesMol Biomed
Zhou L   +12 more
europepmc   +1 more source

Ribosomal proteins can hold a more accurate record of bacterial thermal adaptation compared to rRNA. [PDF]

open access: yesNucleic Acids Res, 2023
van den Elzen A   +4 more
europepmc   +1 more source

Exploring the Potential Role of Ribosomal Proteins to Enhance Potato Resilience in the Face of Changing Climatic Conditions. [PDF]

open access: yesGenes (Basel), 2023
Valencia-Lozano E   +6 more
europepmc   +1 more source

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