Results 201 to 210 of about 1,994,746 (285)

Ribosomal Protein [PDF]

, 2020
openaire   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +1 more source

Ribosomal expansion segment contributes to translation fidelity via N-terminal processing of ribosomal proteins. [PDF]

Nucleic Acids Res
Nagai R, Milam OL, Niwa T, Howell WJ, Best JA, Yoshida H, Freeburg CD, Koomen JM, Fujii K.   +8 more
europepmc   +1 more source

Momordicine I induces ER stress and inhibits OSCC by targeting ribosomal proteins. [PDF]

J Zhejiang Univ Sci B
Kong J, Zhu Z, Hu Y, Zhou S, Gu T, Shen X, Wang H, Yu M, Liu Y.   +8 more
europepmc   +1 more source

METTL3 alters capping enzyme expression and its activity on ribosomal proteins. [PDF]

Sci Rep
Del Valle-Morales D, Romano G, Nigita G, Saviana M, La Ferlita A, Le P, Brown R, Micalo L, Li H, Nana-Sinkam P, Acunzo M.   +10 more
europepmc   +1 more source

β-Sitosterol improves murine ulcerative colitis by inhibiting the expression of ribosomal proteins and the attempted polarization of type 1 macrophages. [PDF]

Int J Colorectal Dis
Geng R, Cao Y, Liu T, Zhong S.
europepmc   +1 more source

Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups

Angewandte Chemie International Edition, EarlyView.
A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari, Leon F. Schwarz, Luca Schlautmann, Kai Schließmann, Christopher Slotman, Nina von Felten, Claus‐Michael Lehr, Rolf Müller, Alexander F. Kiefer, Jörn Piel, Florian Hubrich   +10 more
wiley   +1 more source

Extraribosomal Functions of Bacterial Ribosomal Proteins-An Update, 2023. [PDF]

Int J Mol Sci
Aseev LV, Koledinskaya LS, Boni IV.
europepmc   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

PURE makes PURE: reconstitution of the PURE cell-free system from self-synthesized non-ribosomal proteins

Mottaghi SS, Maerkl SJ.
europepmc   +1 more source