Results 51 to 60 of about 6,124,063 (361)

On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons

bioRxiv, 2018
Ribosomes are known to be assembled in the nucleolus, yet recent studies have revealed robust enrichment and translation of mRNAs encoding ribosomal proteins (RPs) in axons, far away from neuronal cell bodies.
Toshiaki Shigeoka, M. Koppers, H. Wong, Julie Qiaojin Lin, Roberta Cagnetta, A. Dwivedy, Janaina de Freitas Nascimento, Francesca W. van Tartwijk, Florian Ströhl, Jean-Michel Cioni, J. Schaeffer, M. Carrington, C. Kaminski, Hosung Jung, W. Harris, C. Holt   +15 more
semanticscholar   +1 more source

cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]

, 2008
mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA, C. Cirulli, PIETROPAOLO, CONCETTA, PUCCI, PIETRO, RUSSO, ANNAPINA, RUSSO, GIULIA   +5 more
core   +1 more source

Alterations in the ribosomal machinery in cancer and hematologic disorders

Journal of Hematology & Oncology, 2012
Ribosomes are essential components of the protein translation machinery and are composed of more than 80 unique large and small ribosomal proteins. Recent studies show that in addition to their roles in protein translation, ribosomal proteins are also ...
Shenoy Niraj, Kessel Rachel, Bhagat Tushar D, Bhattacharyya Sanchari, Yu Yiting, Mcmahon Christine, Verma Amit   +6 more
doaj   +1 more source

Genome landscapes and bacteriophage codon usage [PDF]

, 2007
Across all kingdoms of biological life, protein-coding genes exhibit unequal usage of synonmous codons. Although alternative theories abound, translational selection has been accepted as an important mechanism that shapes the patterns of codon usage in ...
A Eyre-Walker, A Grosberg, Aviv Regev, C Roessner, D Lubensky, David R. Nelson, E Haggard-Ljungquist, E Zuckerkandl, F Angly, F Sanger, G Bernardi, G Hatfull, G Jenkins, G Kudla, G Modiano, Grzegorz R. Kudla, H Akashi, H Brussow, H Ochman, J Drake, J Lawrence, J Lawrence, J Lobry, J Plotkin, J Weeks, JB Plotkin, JG Lawrence, Joshua B. Plotkin, JR Powell, Julius B. Lucks, K Dittmar, K Sahu, K Sahu, K Sau, K Sau, KB Zeldowich, M Francino, M Pedulla, M Sorensen, N Ashcroft, N Galtier, P Ingvarsson, P Sharp, P Sharp, R Debry, R Edwards, R Fisher, R Hendrix, R Hendrix, R Hendrix, R Hendrix, R Inman, R Juhala, S Altschul, S Gregory, S Karlin, T Ikemura, T Ikemura, T Ikemura, T Kunisawa, WM Fitch   +60 more
core   +6 more sources

Bacterial protein interaction networks: connectivity is ruled by gene conservation, essentiality and function [PDF]

, 2020
Protein-protein interaction (PPI) networks are the backbone of all processes in living cells. In this work we relate conservation, essentiality and functional repertoire of a gene to the connectivity $k$ of the corresponding protein in the PPI networks ...
Cimini, Giulio, Dilucca, Maddalena, Giansanti, Andrea   +2 more
core   +2 more sources

The Streptomyces coelicolor small ORF trpM stimulates growth and morphological development and exerts opposite effects on actinorhodin and calcium-dependent antibiotic production [PDF]

, 2020
In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many
Alberto Vassallo, Andrea Scaloni, Anna Maria Puglia, Emilia Palazzotto, Giovanni Renzone, Giuseppe Gallo, Luigi Botta, Teresa Faddetta   +7 more
core   +2 more sources

Insights into the origin of the nuclear localization signals in conserved ribosomal proteins [PDF]

Nature Communications, 2014
Eukaryotic ribosomal proteins, unlike their bacterial homologues, possess nuclear localization signals (NLSs) to enter the cell nucleus during ribosome assembly.
S. Melnikov, A. Ben-Shem, G. Yusupova, M. Yusupov   +3 more
semanticscholar   +1 more source

Alterations of the mitochondrial proteome caused by the absence of mitochondrial DNA: A proteomic view [PDF]

, 2006
The proper functioning of mitochondria requires that both the mitochondrial and the nuclear genome are functional. To investigate the importance of the mitochondrial genome, which encodes only 13 subunits of the respiratory complexes, the mitochondrial ...
Abdul, Appleby, Armstrong, Bai, Bourges, Buchet, Chai, Claros, Da Cruz, Dey, Du, Garcia, Gianazza, Joseph, King, King, Lescuyer, Luche, Manjasetty, Martinus, Perkins, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Santoni, Sharma, Sharp, Sherer, Singh, Sinha, Suzuki, Tastet, Taylor, Tryoen-Toth, Ugalde, Wiedemann, Zamzami, Zischka   +39 more
core   +4 more sources

The Arabidopsis cytosolic ribosomal proteome: from form to function

Frontiers in Plant Science, 2013
The cytosolic ribosomal proteome of Arabidopsis thaliana has been studied intensively by a range of proteomics approaches and is now one of the best-characterised eukaryotic ribosomal proteomes.
Adam James Carroll
doaj   +1 more source

rRNA maturation in yeast cells depleted of large ribosomal subunit proteins. [PDF]

PLoS ONE, 2009
The structural constituents of the large eukaryotic ribosomal subunit are 3 ribosomal RNAs, namely the 25S, 5.8S and 5S rRNA and about 46 ribosomal proteins (r-proteins).
Gisela Pöll, Tobias Braun, Jelena Jakovljevic, Andreas Neueder, Steffen Jakob, John L Woolford, Herbert Tschochner, Philipp Milkereit   +7 more
doaj   +1 more source