Results 71 to 80 of about 1,994,746 (285)

Bakteri ribosoomide uurimus keemilise modifitseerimise meetoditega [PDF]

, 2010
Väitekirja elektrooniline versioon ei sisalda publikatsioone.Ribosoom on suur makromolekulaarne kompleks, mis kodeerib päriliku informatsiooni valgulisse olemusse.
Pulk, Arto
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Phosphorylation of P-stalk proteins defines the ribosomal state for interaction with auxiliary protein factors

EMBO Reports
Ribosomal action is facilitated by the orchestrated work of trans-acting factors and ribosomal elements, which are subject to regulatory events, often involving phosphorylation.
Kamil Filipek, Sandra Blanchet, Eliza Molestak, Monika Zaciura, Colin Chih-Chien Wu, Patrycja Horbowicz-Drożdżal, Przemysław Grela, Mateusz Zalewski, Sebastian Kmiecik, Alan González-Ibarra, Dawid Krokowski, Przemysław Latoch, Agata L Starosta, Mateusz Mołoń, Yutian Shao, Lidia Borkiewicz, Barbara Michalec-Wawiórka, Leszek Wawiórka, Konrad Kubiński, Katarzyna Socała, Piotr Wlaź, Kyle W Cunningham, Rachel Green, Marina V Rodnina, Marek Tchórzewski   +24 more
doaj   +1 more source

40S ribosome biogenesis co-factors are essential for gametophyte and embryo development [PDF]

, 2013
Ribosome biogenesis is well described in Saccharomyces cerevisiae. In contrast only very little information is available on this pathway in plants. This study presents the characterization of five putative protein co-factors of ribosome biogenesis in ...
Roman Martin, Martin, Roman, Roman Martin (85483), Simm, Stefan, Markus T. Bohnsack, Markus T Bohnsack, Benjamin L. Weis (277837), Stefan Simm, Sandra Missbach (277836), Markus T. Bohnsack (277840), Benjamin L Weis, Enrico Schleiff, Weis, Benjamin L., Sandra Missbach, Bohnsack, Markus, Mißbach, Sandra, Stefan Simm (277838), Schleiff, Enrico, Enrico Schleiff (49377), Lafontaine, Denis, Bohnsack, Markus T., Ra Missbach, Benjamin L. Weis, Schleiff Enrico, Missbach Sandra, Simm Stefan, Bohnsack Markus T., Martin Roman, Weis Benjamin L.   +28 more
core   +2 more sources

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

A new system for naming ribosomal proteins [PDF]

, 2014
A system for naming ribosomal proteins is described that the authors intend to use in the future. They urge others to adopt it. The objective is to eliminate the confusion caused by the assignment of identical names to ribosomal proteins from different ...
Lindahl, Lasse, Steitz, Thomas A, Moore, P, Ortega, Joaquin, Tchorzewski, Marek, Tollervey, David, Dinman, Jonathan D, Moore, Peter B, Lipton, Jeffrey M, Lindhal, L, Lafontaine, Denis Lj, Ellis, Steven R, Noller, Harry F, Beckmann, Roland, Panse, VG, Spahn, Christian Mt, Williamson, JR, Lund University., Tchorzewski, M, Williamson, James R, Liljas, Anders,, Beckmann, R, Ban, Nenad, Panse, Vikram Govind, Wilson, Daniel, Dragon, François, Yonath, Ada, Steitz, TA, Liljas, A, Warren, AJ, Cate, JH, Noller, HF, Ortega, J, Tollervey, D, Yusupov, M, Spahn, CM, Yonath, A, Yusupov, Marat, Ellis, SR, Cate, Jamie Hd, Ramakrishnan, V, Wilson, D, Lipton, JM, Lafontaine, Denis, Warren, Alan J, Dinman, JD, McAlear, MA, McAlear, Michael A, Dragon, F, Liljas, Anders, Ban, N., Tchorzewski M, Ortega J, Steitz, Thomas, Ban N, Beckmann, R., Lindahl, L., Dinman JD, Lindahl L, Beckmann R, Moore, Peter, Yusupov, M., McAlear MA, Yonath A, Dragon F, Williamson JR, Ellis SR, Mcalear, Michael, Panse VG, Dragon, F., Ellis, Steven, Lipton, Jeffrey, Williamson, James, Dinman, J. D., Liljas A, Ellis, S. R., Dinman, Jonathan, Cate, J. H. D., Noller, Harry, Ramakrishnan V, Yusupov M, Lipton JM, Lafontaine DL, Tollervey D, Warren, Alan, Lipton, J. M., Cate JH, Steitz TA, Moore PB, Spahn CM, Lafontaine, D. L. J., Warren AJ, Wilson D, Noller HF, +15 additional authors   +94 more
core   +3 more sources

RsfA (YbeB) proteins are conserved ribosomal silencing factors. [PDF]

PLoS Genetics, 2012
The YbeB (DUF143) family of uncharacterized proteins is encoded by almost all bacterial and eukaryotic genomes but not archaea. While they have been shown to be associated with ribosomes, their molecular function remains unclear.
Roman Häuser, Markus Pech, Jaroslaw Kijek, Hiroshi Yamamoto, Björn Titz, Florian Naeve, Andrey Tovchigrechko, Kaori Yamamoto, Witold Szaflarski, Nono Takeuchi, Thorsten Stellberger, Markus E Diefenbacher, Knud H Nierhaus, Peter Uetz   +13 more
doaj   +1 more source

Are ribosomal proteins present at transcription sites on or off ribosomal subunits?

, 2010
RPs (ribosomal proteins) are main components of the ribosome having essential functions in its biogenesis, function and structural integrity. Although most of the RP molecules are in the cytoplasm, being incorporated into translating ribosomes, some RPs ...
De, S, Saverio Brogna, Brogna, Saverio, Sandip De   +3 more
core   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Structure-to-Function Computational Prediction of a Subset of Ribosomal Proteins for the Small Ribosome Subunit [PDF]

, 2015
Extra-ribosomal functions of ribosomal proteins have been widely accepted albeit an incomplete understanding of these roles. Standard experimental studies have limited usefulness in defining the complete biological significance of ribosomal proteins ...
Ui-Hang, Edmund Sim, Chin-Ming, Er
core   +1 more source