Results 1 to 10 of about 1,346,883 (382)

Structural basis of ribosomal RNA transcription regulation

Nature Communications, 2021
Ribosomal RNA (rRNA) expression is regulated at the initiation stage of RNA synthesis. Here, the authors report cryo-EM structures of E. coli RNA polymerase and rRNA promoter complex with DksA/ppGpp on the way to open complex formation, identifying key ...
Yeonoh Shin, M. Zuhaib Qayyum, Danil Pupov, Daria Esyunina, Andrey Kulbachinskiy, Katsuhiko S. Murakami   +5 more
doaj   +2 more sources

Folding molecular origami from ribosomal RNA [PDF]

Journal of Nanobiotechnology
Approximately 80 percent of the total RNA in cells is ribosomal RNA (rRNA), making it an abundant and inexpensive natural source of long, single-stranded nucleic acid, which could be used as raw material for the fabrication of molecular origami.
Anastasia Shapiro, Noah Joseph, Nadav Mellul, Almogit Abu-Horowitz, Boaz Mizrahi, Ido Bachelet   +5 more
doaj   +2 more sources

RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability [PDF]

RNA Biology
Transcription is a major contributor to genomic instability. The ribosomal RNA (rDNA) gene locus consists of a head-to-tail repeat of the most actively transcribed genes in the genome.
Christophe Normand, Christophe Dez, Lise Dauban, Sophie Queille, Sarah Danché, Sarra Abderrahmane, Frederic Beckouet, Olivier Gadal   +7 more
doaj   +2 more sources

Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

Biomolecules, 2018
Ribosomal RNAs, the most abundant cellular RNA species, have evolved as the structural scaffold and the catalytic center of protein synthesis in every living organism.
Maxime Aubert, Marie-Françoise O’Donohue, Simon Lebaron, Pierre-Emmanuel Gleizes   +3 more
doaj   +2 more sources

Dual RNA-seq in filarial nematodes and Wolbachia endosymbionts using RNase H based ribosomal RNA depletion [PDF]

Frontiers in Microbiology
Lymphatic filariasis is caused by parasitic nematodes and is a leading cause of disability worldwide. Many filarial worms contain the bacterium Wolbachia as an obligate endosymbiont.
Lindsey J. Cantin, Vanessa Gregory, Laura N. Blum, Jeremy M. Foster   +3 more
doaj   +2 more sources

Evidence for further non-coding RNA genes in the fungal rDNA region [PDF]

MycoKeys, 2022
Non-coding RNA (ncRNA) genes play important, but incompletely understood, roles in various cellular processes, notably translation and gene regulation.
Magnus Alm Rosenblad, Ellen Larsson, Arttapon Walker, Naritsada Thongklang, Christian Wurzbacher, R. Henrik Nilsson   +5 more
doaj   +3 more sources

A Ribosome Without RNA [PDF]

Frontiers in Ecology and Evolution, 2015
It was Francis Crick who first asked why the ribosome contains so much RNA, and discussed the implications of this for the direct flow of genetic information from DNA to protein. Remarkable advances in our understanding of the ribosome and protein synthesis, including the recent publication of two mammalian mitochondrial ribosome structures, have shed ...
Harold S. Bernhardt, Warren P. Tate
openaire   +2 more sources

Complete mitochondrial genome of the recently discovered multivoltine Graphium (Pazala) confucius Hu, Duan & Cotton, 2018 (Lepidoptera: Papilionidae)

Mitochondrial DNA. Part B. Resources, 2022
Graphium (Pazala) confucius Hu, Duan & Cotton, 2018 is a recently discovered, wide ranging, multivoltine swordtail butterfly in China and Vietnam.
Fu-Rong He, Xin Zhang, Shao-Ji Hu
doaj   +1 more source

Ribosomal control in RNA virus-infected cells

Frontiers in Microbiology, 2022
Viruses are strictly intracellular parasites requiring host cellular functions to complete their reproduction cycle involving virus infection of host cell, viral genome replication, viral protein translation, and virion release.
Xiao Wang, Jie Zhu, Da Zhang, Guangqing Liu   +3 more
doaj   +1 more source

Varying strength of selection contributes to the intragenomic diversity of rRNA genes

Nature Communications, 2022
Ribosomal RNA genes are abundant in eukaryotic genomes and code for the universal and essential RNA components of the ribosome. This study uncovers high sequence diversity of the genes within a single species and discusses the contribution of selection ...
Daniel Sultanov, Andreas Hochwagen
doaj   +1 more source