Results 1 to 10 of about 1,591,440 (405)

Transcription-translation coupling: direct interactions of RNA polymerase with ribosomes and ribosomal subunits. [PDF]

Nucleic Acids Research, 2017
In prokaryotes, RNA polymerase and ribosomes can bind concurrently to the same RNA transcript, leading to the functional coupling of transcription and translation.
Blaha, Gregor M, Conn, Adam B, Diggs, Stephen, Fan, Haitian, Gamper, Howard B, Hahm, Joseph, Hou, Ya-Ming, O'Leary, Seán E, Wang, Yinsheng, Williams, Preston B   +9 more
core   +2 more sources

Structural basis of ribosomal RNA transcription regulation

Nature Communications, 2021
Ribosomal RNA (rRNA) expression is regulated at the initiation stage of RNA synthesis. Here, the authors report cryo-EM structures of E. coli RNA polymerase and rRNA promoter complex with DksA/ppGpp on the way to open complex formation, identifying key ...
Yeonoh Shin, M. Zuhaib Qayyum, Danil Pupov, Daria Esyunina, Andrey Kulbachinskiy, Katsuhiko S. Murakami   +5 more
doaj   +2 more sources

Folding molecular origami from ribosomal RNA [PDF]

Journal of Nanobiotechnology
Approximately 80 percent of the total RNA in cells is ribosomal RNA (rRNA), making it an abundant and inexpensive natural source of long, single-stranded nucleic acid, which could be used as raw material for the fabrication of molecular origami.
Anastasia Shapiro, Noah Joseph, Nadav Mellul, Almogit Abu-Horowitz, Boaz Mizrahi, Ido Bachelet   +5 more
doaj   +2 more sources

Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

Biomolecules, 2018
Ribosomal RNAs, the most abundant cellular RNA species, have evolved as the structural scaffold and the catalytic center of protein synthesis in every living organism.
Maxime Aubert, Marie-Françoise O’Donohue, Simon Lebaron, Pierre-Emmanuel Gleizes   +3 more
doaj   +2 more sources

Dual RNA-seq in filarial nematodes and Wolbachia endosymbionts using RNase H based ribosomal RNA depletion [PDF]

Frontiers in Microbiology
Lymphatic filariasis is caused by parasitic nematodes and is a leading cause of disability worldwide. Many filarial worms contain the bacterium Wolbachia as an obligate endosymbiont.
Lindsey J. Cantin, Vanessa Gregory, Laura N. Blum, Jeremy M. Foster   +3 more
doaj   +2 more sources

Evidence for further non-coding RNA genes in the fungal rDNA region [PDF]

MycoKeys, 2022
Non-coding RNA (ncRNA) genes play important, but incompletely understood, roles in various cellular processes, notably translation and gene regulation.
Magnus Alm Rosenblad, Ellen Larsson, Arttapon Walker, Naritsada Thongklang, Christian Wurzbacher, R. Henrik Nilsson   +5 more
doaj   +3 more sources

Complete mitochondrial genome of the recently discovered multivoltine Graphium (Pazala) confucius Hu, Duan & Cotton, 2018 (Lepidoptera: Papilionidae)

Mitochondrial DNA. Part B. Resources, 2022
Graphium (Pazala) confucius Hu, Duan & Cotton, 2018 is a recently discovered, wide ranging, multivoltine swordtail butterfly in China and Vietnam.
Fu-Rong He, Xin Zhang, Shao-Ji Hu
doaj   +1 more source

Comprehensive identification of diverse ribosomal RNA modifications by targeted nanopore direct RNA sequencing and JACUSA2

RNA Biology, 2023
Ribosomal RNAs are decorated by numerous post-transcriptional modifications whose exact roles in ribosome biogenesis, function, and human pathophysiology remain largely unknown.
Isabel S. Naarmann-de Vries, Christiane Zorbas, Amina Lemsara, Michael Piechotta, Felix G. M. Ernst, Ludivine Wacheul, Denis L. J. Lafontaine, Christoph Dieterich   +7 more
doaj   +1 more source

Varying strength of selection contributes to the intragenomic diversity of rRNA genes

Nature Communications, 2022
Ribosomal RNA genes are abundant in eukaryotic genomes and code for the universal and essential RNA components of the ribosome. This study uncovers high sequence diversity of the genes within a single species and discusses the contribution of selection ...
Daniel Sultanov, Andreas Hochwagen
doaj   +1 more source

Ribosomal control in RNA virus-infected cells

Frontiers in Microbiology, 2022
Viruses are strictly intracellular parasites requiring host cellular functions to complete their reproduction cycle involving virus infection of host cell, viral genome replication, viral protein translation, and virion release.
Xiao Wang, Jie Zhu, Da Zhang, Guangqing Liu   +3 more
doaj   +1 more source