Results 11 to 20 of about 1,110,020 (298)

A Ribosome Without RNA [PDF]

Frontiers in Ecology and Evolution, 2015
It was Francis Crick who first asked why the ribosome contains so much RNA, and discussed the implications of this for the direct flow of genetic information from DNA to protein. Remarkable advances in our understanding of the ribosome and protein synthesis, including the recent publication of two mammalian mitochondrial ribosome structures, have shed ...
Bernhardt, Harold S., Tate, Warren P.
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Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]

, 2010
For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
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The mitochondrial ribosome and ribosomal RNA of the chick [PDF]

FEBS Letters, 1971
Reports have appeared on large molecular weight RNAs associated with the mitochondria of higher organisms. These include HeLa cells [ 1 ] , BHK-2 1 cells [2] , mouse L-cells [3,4] , rat liver [4, S] and Xenopus ovary [6] . This RNA consists of two predominant species found to be 17 S and 13 S by sedimentation [2, 31 .
Rabbitts, Terence H., Work, T.S.
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Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan [PDF]

, 2015
Several pathways modulating longevity and stress resistance converge on translation by targeting ribosomal proteins or initiation factors, but whether this involves modifications of ribosomal RNA is unclear.
Wilson, Iain B H, Mohr, Thomas, Mattanovich, Diethard, Breitenbach, Michael, Linder, Angela, Karl, Thomas, Amring, Manuela, Wilson, Iain B.H., Grillari-Voglauer, Regina, Polacek, Norbert, Angerer, Tina B., Rinnerthaler, Mark, Angerer, Tina B, Pircher, Andreas, Schosserer, Markus, Grillari, Johannes, Sharma, Sunny, Minois, Nadege, Breitenbach-Koller, Hannelore, Entian, Karl-Dieter, Kriegner, Albert, Steiger, Matthias, Breitenbach-Koller, Lore, Pfeifenberger, Sigrid, Dellago, Hanna, Calle-Perez, Alfonso, Brandl, Clemens, Weinhäusel, Andreas, Harreither, Eva, Kos, Martin, Sonntagbauer, Markus, Gerstl, Matthias Peter   +31 more
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KnotInFrame: prediction of –1 ribosomal frameshift events [PDF]

, 2008
Theis C, Reeder J, Giegerich R. KnotInFrame: prediction of –1 ribosomal frameshift events. Nucleic Acids Research. 2008;36(18):6013-6020.Programmed –1 ribosomal frameshift (–1 PRF) allows for alternative reading frames within one mRNA.
Corinna Theis, Theis, Corinna, Jens Reeder, Robert Giegerich, Reeder, Jens, Giegerich, Robert   +5 more
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Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. [PDF]

, 2005
The protozoan parasite Leishmania belongs to the most ancient eukaryotic lineages and this is reflected in several distinctive biological features, such as eukaryotic polycistronic transcription and RNA trans-splicing.
Laurent, T., Chappuis, F., Llanos-Cuentas, A., Llanos-Cuentas, A, V. YARDLEY, F. CHAPPUIS, Laurent, T, T. LAURENT, Dujardin, J. C., Vandesompele, J, J.-C. DUJARDIN, DE DONCKER, S, S. RIJAL, Decuypere, S., S. DECUYPERE, Yardley, V, De Donckeri, S, Vandesompele, Jo, Rijal, S., J. AREVALO, Vandesompele, J., S. DE DONCKER, J. VANDESOMPELE, Yardley, V., Chappuis, F, Arevalo, J., Arevalo, J, Rijal, S, De Doncker, S., A. LLANOS-CUENTAS, Dujardin, JC, Decuypere, S   +31 more
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Epitranscriptomics of Mammalian Mitochondrial Ribosomal RNA

Cells, 2020
Modified nucleotides are present in all ribosomal RNA molecules. Mitochondrial ribosomes are unique to have a set of methylated residues that includes universally conserved ones, those that could be found either in bacterial or in archaeal/eukaryotic ...
Ivan Laptev, Olga Dontsova, Petr Sergiev
doaj   +1 more source

Toxocara canis (Ascaridida: Nematoda): Mitochondrial gene content, arrangement and composition compared with other Toxocara species

Sri Lankan Journal of Infectious Diseases, 2014
Introduction: The complete mitochondrial (mt) genomes of nematodes sequenced thus far are circular and small in length, containing 37 genes, including 12–13 protein-coding genes: namely, cytochrome oxidase subunits 1–3 (cox1–3), nicotinamide adenine ...
S Wickramasinghe, L Yatawara, T Agatsuma
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L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy [PDF]

, 2006
Ribosomal proteins are assumed to stabilize specific RNA structures and promote compact folding of the large rRNA. The conformational dynamics of the protein between the bound and unbound state play an important role in the binding process.
Wöhnert, Jens, Hendrik R. A. Jonker, Harald Schwalbe, Ilin, Serge, S. Kaspar Grimm, Grimm, Steffen Kaspar, Jens Wöhnert, Jonker, Hendrik R. A., Schwalbe, Harald (Prof. Dr.), Serge Ilin   +9 more
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Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA. [PDF]

PLoS ONE, 2014
Intact RNA from exosomes/microvesicles (collectively referred to as microvesicles) has sparked much interest as potential biomarkers for the non-invasive analysis of disease.
Kevin C Miranda, Daniel T Bond, Joshua Z Levin, Xian Adiconis, Andrey Sivachenko, Carsten Russ, Dennis Brown, Chad Nusbaum, Leileata M Russo   +8 more
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