Results 171 to 180 of about 1,584,172 (286)

Basis for selective drug evasion of an aminoglycoside-resistance ribosomal RNA modification. [PDF]

Nat Commun
Dey D, Mattingly JM, Zelinskaya N, Dunham CM, Conn GL.   +4 more
europepmc   +1 more source

Complete nucleotide sequence of a 16S ribosomal RNA gene from Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America, 1978
J. Brosius, M. L. Palmer, P. J. Kennedy, H. Noller   +3 more
semanticscholar   +1 more source

Programmable RNA N6,2´‐O‐Dimethyladenosine Editing

Advanced Science, EarlyView.
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li, Xiangmin Tan, Yaran Liu, Yongquan He, Bo Yuan, Ping Wang, Guangzhi Ma, Mengzhe Guo, Jian Zhou, Qiang Sun   +9 more
wiley   +1 more source

Correction: A systematic algorithm using 16S ribosomal RNA for accurate diagnosis of pneumonia pathogens. [PDF]

Sci Rep
Kurniawan FD, Alia D, Shiraishi M, Higo M, Inoue Y, Hagiwara K.   +5 more
europepmc   +1 more source

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

The Role of Chemistry Across Disciplines From Humanities to Life Sciences in Understanding Complexity and Emergence

Angewandte Chemie, EarlyView.
This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe, Josef Wachtveitl, Alexander Heckel, Florian Buhr, Sabrina Toews, Thomas M. Schimmer   +5 more
wiley   +2 more sources

MazF endoribonuclease promotes resolution of transcription-replication conflicts at ribosomal RNA genes in Escherichia coli. [PDF]

Nucleic Acids Res
Fleurier S, Matic I.
europepmc   +1 more source

Rapid Method for Coextraction of DNA and RNA from Natural Environments for Analysis of Ribosomal DNA- and rRNA-Based Microbial Community Composition

Applied and Environmental Microbiology, 2000
R. Griffiths, A. Whiteley, A. O'donnell, M. Bailey   +3 more
semanticscholar   +1 more source

Combined Long‐Read Genome and Transcriptome Sequencing Establishes Novel Variants in MEGF8 as the Cause for Carpenter Syndrome Type 2

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Carpenter syndrome type 2 (CRPT2) is a rare autosomal recessive disease mainly characterized by craniosynostosis and polysyndactyly. CRPT2 is the rarer subtype of Carpenter syndrome (CRPTS) and is caused by biallelic variants in the multiple epidermal growth factor‐like domains 8 gene (MEGF8).
Kiana Rashidi, Bhavi P. Modi, Phillip A. Richmond, Massimo Mangino, Loryn Byres, Cassie McDonald, Joshua Dalmann, Simran Samra, Kate L. Del Bel, Anna Lehman, Jessica L. Zambonin, Stuart E. Turvey   +11 more
wiley   +1 more source

Fibrillarin-mediated ribosomal RNA maturation is a novel therapeutic vulnerability in triple-negative breast cancer. [PDF]

Breast Cancer Res
Jouines C, Lo Monaco P, Gaucherot A, Radermecker J, Isaac C, Bourdelais F, Monet MA, Meyer M, Chalabi-Dchar M, Nguyen Van Long F, Baillon L, Froment C, Marcoux J, Vanbelle C, Fenouil T, Durand S, Giraud S, Diaz JJ, Marcel V, Catez F.   +19 more
europepmc   +1 more source