Results 111 to 120 of about 3,389,293 (247)
Ribosome-inactivating protein-containing conjugates for therapeutic use
A number of plant proteins inhibit protein synthesis by irreversibly inactivating the 60S ribosomal subunit in a catalytical, that is, enzymatic, manner. For this property, they are called ribosome-inactivating proteins (RIPs).
COLOMBATTI, Marco +2 more
core +1 more source
Enterovirus infections in children
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen +11 more
wiley +1 more source
Ribosome-inactivating proteins : current status and biomedical applications
Ribosome-inactivating proteins (RIPs) are mainly present in plants and function to inhibit protein synthesis through the removal of adenine residues from eukaryotic ribosomal RNA (rRNA).
R Gupta (7722986) +3 more
core
Supervised Protein Structure Classification Using Topological Persistence With DeltaFold
ABSTRACT Recent advances in protein structure prediction have considerably increased the number of available structures, underscoring the need for scalable and accurate methods to compare and classify this huge amount of data. Current approaches based on sequence alignment or structural superposition often lack sensitivity and/or are computationally ...
Joseph Nardin‐Gennequin +3 more
wiley +1 more source
Structural and functional characterization of the cytotoxic protein ledodin, an atypical ribosome-inactivating protein from shiitake mushroom (Lentinula edodes). [PDF]
Citores L +7 more
europepmc +1 more source
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley +1 more source
Identification of Yeast Protein Sequences With Similarity to the ESCRT‐III Protein Snf7
ABSTRACT Endosomal sorting complex required for transport (ESCRT‐III) is a membrane remodeling complex involved in a large number of cellular processes. It appears to perform an essential function in eukaryotes, since to date no eukaryotic organism completely devoid of ESCRT‐III has been found.
Thomas Brune, Ralf Kölling
wiley +1 more source
Comparative analysis of the interaction sites of curcin, curcin C with adenine
The ribosome-inactivating proteins of Jatropha curcas curcin and curcin C have antitumor activity, but the activity level of the latter is significantly higher than the former.
WU Peng +3 more
doaj
Differential effects of the recombinant type 1 ribosome-inactivating protein, OsRIP1, on growth of PSB-D and BY-2 cells. [PDF]
Chen S +3 more
europepmc +1 more source
ABSTRACT The knockout strain collection of Saccharomyces cerevisiae has served as a valuable resource for functional genomics and yeast‐based biotechnology studies. A comprehensive single‐gene knockout strain collection, covering nearly all non‐essential genes, together with complementary mutant collections for essential genes, including temperature ...
Takashi Hirasawa
wiley +1 more source

