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Ribosome-inactivating proteins (RIPs) of wild Oregon cucumber (Marah oreganus).

Biological chemistry, 1998
Two type 1 RIPs, designated as MOR-I and MOR-II, have been isolated from Marah oreganus (manroot) seed extract. They are similar but not identical to trichosanthin, a type 1 RIP in the same family. MOR-I and MOR-II are monomeric proteins with molecular weights of 27989.0 and 27632.8 respectively and have pI values greater than 8.8.
N J, Shih   +5 more
openaire   +1 more source

Structural insights into the toxicity of type II ribosome inactivating proteins (RIPs): a molecular dynamics study

Journal of Biomolecular Structure and Dynamics
Ribosome Inactivating Proteins (RIPs) act by irreversibly depurinating the 28S rRNA ricin-sarcin loop (SRL) of the eukaryotic ribosome resulting in protein synthesis inhibition. In general, they consist of two variants: Type I which is single chained (∼30 kDa), and Type II, a more toxic variant which is a Type I N-glycosidase chain covalently linked to
Pavan K, Madasu, Thyageshwar, Chandran
openaire   +2 more sources

Immunology of RIPs and their Immunotoxins, in Ribosome-inactivating Proteins: Ricin and Related Proteins

2014
This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide ...
FRACASSO, Giulio, COLOMBATTI, Marco
openaire   +1 more source

Reductive activation of type 2 ribosome inactivating proteins (RIPs 2) is promoted by transmembrane thioredoxin-related protein (TMX)

2012
Members of the type 2 ribosome-inactivating proteins (RIPs) family (e.g. ricin, abrin) are potent cytotoxins showing a strong lethal activity towards eukaryotic cells. Type 2 RIPs contain two polypeptide chains (usually named A, for activity, and B, for binding) linked by a disulfide bond.
PASETTO, Matteo   +5 more
openaire   +1 more source

Elevated expression of ribosome-inactivating protein (RIP) genes in potyvirus-resistant watermelon in response to viral infection

Canadian Journal of Plant Pathology, 2022
Bidisha Chanda   +4 more
openaire   +1 more source

A cytotoxic type-2 ribosome inactivating protein (from leafless mistletoe) lacking sugar binding activity

International Journal of Biological Macromolecules, 2011
Mrinal Kumar Das   +2 more
exaly  

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