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Ribosome-inactivating proteins (RIPs) of wild Oregon cucumber (Marah oreganus).
Biological chemistry, 1998Two type 1 RIPs, designated as MOR-I and MOR-II, have been isolated from Marah oreganus (manroot) seed extract. They are similar but not identical to trichosanthin, a type 1 RIP in the same family. MOR-I and MOR-II are monomeric proteins with molecular weights of 27989.0 and 27632.8 respectively and have pI values greater than 8.8.
N J, Shih +5 more
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Journal of Biomolecular Structure and Dynamics
Ribosome Inactivating Proteins (RIPs) act by irreversibly depurinating the 28S rRNA ricin-sarcin loop (SRL) of the eukaryotic ribosome resulting in protein synthesis inhibition. In general, they consist of two variants: Type I which is single chained (∼30 kDa), and Type II, a more toxic variant which is a Type I N-glycosidase chain covalently linked to
Pavan K, Madasu, Thyageshwar, Chandran
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Ribosome Inactivating Proteins (RIPs) act by irreversibly depurinating the 28S rRNA ricin-sarcin loop (SRL) of the eukaryotic ribosome resulting in protein synthesis inhibition. In general, they consist of two variants: Type I which is single chained (∼30 kDa), and Type II, a more toxic variant which is a Type I N-glycosidase chain covalently linked to
Pavan K, Madasu, Thyageshwar, Chandran
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2014
This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide ...
FRACASSO, Giulio, COLOMBATTI, Marco
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This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide ...
FRACASSO, Giulio, COLOMBATTI, Marco
openaire +1 more source
2012
Members of the type 2 ribosome-inactivating proteins (RIPs) family (e.g. ricin, abrin) are potent cytotoxins showing a strong lethal activity towards eukaryotic cells. Type 2 RIPs contain two polypeptide chains (usually named A, for activity, and B, for binding) linked by a disulfide bond.
PASETTO, Matteo +5 more
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Members of the type 2 ribosome-inactivating proteins (RIPs) family (e.g. ricin, abrin) are potent cytotoxins showing a strong lethal activity towards eukaryotic cells. Type 2 RIPs contain two polypeptide chains (usually named A, for activity, and B, for binding) linked by a disulfide bond.
PASETTO, Matteo +5 more
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Biotechnological Potential of Ribosome Inactivating Proteins (RIPs)
2015DI MARO, Antimo, Pizzo E., Girbes T.
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