Results 121 to 130 of about 24,039 (208)

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Elimination of Ribosome Inactivating Factors Improves the Efficiency of Bacillus subtilis and Saccharomyces cerevisiae Cell-Free Translation Systems

Frontiers in Microbiology, 2018
Cell-free translation systems based on cellular lysates optimized for in vitro protein synthesis have multiple applications both in basic and applied science, ranging from studies of translational regulation to cell-free production of proteins and ...
Tetiana Brodiazhenko, Tetiana Brodiazhenko, Tetiana Brodiazhenko, Marcus J. O. Johansson, Hiraku Takada, Hiraku Takada, Tracy Nissan, Tracy Nissan, Vasili Hauryliuk, Vasili Hauryliuk, Vasili Hauryliuk, Victoriia Murina, Victoriia Murina   +12 more
doaj   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

TM9SF2 Maintains Golgi Integrity and Regulates Ricin-Induced Cytotoxicity

Toxins
TM9SF2 belongs to a family of highly conserved nonaspanin proteins, and has been frequently identified as one of the important host factors for a plethora of lethal pathogens and toxins in previous genome-wide screening studies.
Yue Meng, Hongzhi Wan, Xinyu Wang, Lina Zhang, Ruozheng Xin, Lingyu Li, Yuhui Wang, Chengwang Xu, Hui Peng, Lu Sun, Bo Wang, Xiaotao Duan   +11 more
doaj   +1 more source

Isolation, Characterization and Biological Action of Type-1 Ribosome-Inactivating Proteins from Tissues of Salsola soda L. [PDF]

Toxins (Basel), 2022
Landi N, Ragucci S, Citores L, Clemente A, Hussain HZF, Iglesias R, Ferreras JM, Di Maro A.   +7 more
europepmc   +1 more source

TaRIP2 Positively Regulates Wheat Pollen Wall Formation Through MYB80‐Controlled Lipid Metabolism

Plant Biotechnology Journal, EarlyView.
ABSTRACT Male‐sterile genes and mutants are critical for hybrid seed production in monocotyledonous crops. Lipids are essential structural components of male reproductive organs, such as the anther and pollen. Here, we show that the pollen‐preferential gene TaRIP2 is essential for wheat anther development and pollen formation. RT‐qPCR analysis revealed
Ran Han, Aifeng Liu, Guang Qi, Chunhao Fang, XiaoLu Wang, Wenjing Xu, Kai Wang, Jihu Li, Qingqi Fan, Dungong Cheng, Faji Li, Haosheng Li, Jianjun Liu, Genying Li, Cheng Liu   +14 more
wiley   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Alteraciones histológicas causadas por la administración intraperitoneal de ebulina en ratones [PDF]

, 2017
La ebulina es una proteína inhibidora de ribosomas tipo 2 con actividad lectina (RIL) aislada del saúco enano. Los frutos del saúco se han consumido desde la antigüedad por sus atribuidos efectos medicinales.
Vicente Pardo, Andrea
core  

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source