Results 131 to 140 of about 24,039 (208)
The tasiR‐ARF pathway in plants: origin, functions, and interplay of miR‐390, tasiRNAs and ARF3
Trans‐acting small interfering RNAs that silence a subset of Auxin Response Factors are crucial for plant growth, developmental timing, proper organ patterning, and coping with stress. Abstract Trans‐acting small interfering RNA (tasiRNAs) are a special type of endogenous small RNAs (sRNAs) found only in plants.
B. A. López‐Ruiz +4 more
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Rare DMD Gene Duplication in a Lebanese Child With Duchene Muscular Dystrophy
ABSTRACT A five‐year‐old boy with clinical features of Duchenne muscular dystrophy was found to have a rare de novo DMD exon 2–9 duplication. Reporting such atypical duplications improves genotype–phenotype interpretation and highlights the need for multidisciplinary care, particularly in resource‐limited settings.
Nada Assaf +4 more
wiley +1 more source
A case of accidental Ricin poisoning [PDF]
A case report of accidental, mild ricin poisoning by ingestion of ten Castor beans by a 70 year old man. The clinical presentation is followed by a discussion about the toxicity of ricin, its use and misuse and the contrast between the toxicity of pure ...
Cachia, Mario J., Despott, Edward
core
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley +1 more source
Isolation and Characterization of Lectins from Ricinus communis [PDF]
Lectins are proteins which are well distributed in nature. They are found in both plants and animals but plants are the richest source. On the surface of the cell lectins are attached with their sugar binding site. Lectins are found to be toxic, as it is
Bhoi, Archana
core
Ricinus Communis: Nutritional Importance, Health Benefits, and Industrial Applications
The current paper summarizes the nutritional composition, phytochemistry, health benefits, safety studies, and applications of castor beans and their oil. Moreover, the diverse bioactive compounds, including saponins, emodins, terpenoids, anthraquinones, flavonoids, steroids, and alkaloids, exhibit therapeutic properties such as antioxidant, anticancer,
Hassan Raza +13 more
wiley +1 more source
Crystallization and preliminary X-ray studies of snake gourd lectin: homology with type II ribosome-inactivating proteins [PDF]
Arulanandam, Jeyaprakash +6 more
core +1 more source
ABSTRACT Background and Aims Acne vulgaris is a frequent skin disorder, affecting a large part of the population worldwide, and strongly influencing not only the physical but also the mental aspects of health. The choice of therapy for acne vulgaris is a very difficult one because the multifactorial causality of the disease and interindividual ...
Mobina Tajdari +5 more
wiley +1 more source
Progress in RNA‐Targeted Therapeutics for Human Diseases
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang +10 more
wiley +1 more source

