Results 131 to 140 of about 13,819 (234)

A Scaffoldomics Platform for Modular In Vivo Enzyme Colocalisation and Its Application to Naringenin Biosynthesis

open access: yesMicrobial Biotechnology, Volume 19, Issue 3, March 2026.
A hierarchical assembly system was established in which the coding sequences for four docking enzymes and a scaffold are co‐assembled onto a single plasmid, thereby establishing a ‘scaffoldomics’ platform for the optimisation of multi‐enzyme biosynthetic pathways.
Marte Elias   +5 more
wiley   +1 more source

Structure-function study of maize ribosome-inactivating protein: implications for the internal inactivation region and the sole glutamate in the active site [PDF]

open access: gold, 2007
Amanda Nga-Sze Mak   +7 more
openalex   +1 more source

Heterologous plastoquinone production using a newly identified O2‐dependent cyanobacterial hydroxylase

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1708-1726, March 2026.
In this study, we confirm that PlqH is the hydroxylase operating in plastoquinone biosynthesis in photosynthetic cyanobacteria (Cyanobacteriia). Our phylogenetic analyses demonstrate that cyanobacterial PlqH homologues originated from hydroxylases involved in ubiquinone biosynthesis in bacteria. Plastoquinone production in Escherichia coli was achieved
Morgane Roger‐Margueritat   +7 more
wiley   +1 more source

Current status of ribosome inactivating proteins.

open access: yesIndian journal of biochemistry & biophysics, 2000
Ribosome inactivating proteins (RIPs) are a group of naturally occurring plant proteins with a RNA-N-glycosidases activity which depurinate rRNA at a specific universally conserved position (i.e. cleavage of N-glycosidic bond of a specific adenine of 28S rRNA).
R C, Singh, V, Singh
openaire   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

open access: yesJournal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron   +3 more
wiley   +1 more source

The tasiR‐ARF pathway in plants: origin, functions, and interplay of miR‐390, tasiRNAs and ARF3

open access: yesPlant Biology, Volume 28, Issue 2, Page 328-344, March 2026.
Trans‐acting small interfering RNAs that silence a subset of Auxin Response Factors are crucial for plant growth, developmental timing, proper organ patterning, and coping with stress. Abstract Trans‐acting small interfering RNA (tasiRNAs) are a special type of endogenous small RNAs (sRNAs) found only in plants.
B. A. López‐Ruiz   +4 more
wiley   +1 more source

An unusual type I ribosome-inactivating protein from Agrostemma githago L. [PDF]

open access: gold, 2020
Christoph Weise   +7 more
openalex   +1 more source

Characterization of Phytoene Desaturase Knockout Carotenoid‐Deficient Microalgal Mutants Generated by Cas9‐Ribonucleoprotein Complexes

open access: yesPhysiologia Plantarum, Volume 178, Issue 2, March/April 2026.
ABSTRACT Phytoene desaturase (PDS; EC 1.3.5.5) is a key enzyme of the carotenoid biosynthetic pathway, catalyzing the desaturation of phytoene, precursor of all carotenoids. In this study, several PDS‐knockout (PDS‐KO) transformants of the chlorophyte microalga Chlamydomonas reinhardtii were generated using a reverse genetics strategy. Two single guide
Ana Molina‐Márquez   +5 more
wiley   +1 more source

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