Results 101 to 110 of about 406,930 (327)
The ribosome quality control factors Asc1 and Hel2 regulate the expression of HSP70 during heat shock and recovery [PDF]
, 2022 Lokha R. Alagar Boopathy +6 more
openalex +1 more source
Impaired ribosome biogenesis: mechanisms and relevance to cancer and aging
Aging, 2019 The biosynthesis of ribosomes is a complex process that requires the coordinated action of many factors and a huge energy investment from the cell. Ribosomes are essential for protein production, and thus for cellular survival, growth and proliferation ...
Zsófia Turi +3 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras +19 more
wiley +1 more source
eLife, 2017 The eukaryotic pre-initiation complex (PIC) bearing the eIF2·GTP·Met-tRNAiMet ternary complex (TC) scans the mRNA for an AUG codon in favorable context.
Jyothsna Visweswaraiah +1 more
doaj +1 more source
Ribosome Profiling: Global Views of Translation.
Cold Spring Harbor Perspectives in Biology, 2018 The translation of messenger RNA (mRNA) into protein and the folding of the resulting protein into an active form are prerequisites for virtually every cellular process and represent the single largest investment of energy by cells.
Nicholas T. Ingolia +2 more
semanticscholar +1 more source
The Anisotropic Adsorption of De Novo Allosteric Two‐Component Protein Fibers on Mica Surfaces
Advanced Functional Materials, EarlyView.In this study, the interfacial behavior of de novo designed proteins that self‐assemble into tubular architectures with distinct morphologies — small (S), large (L), and helical (H) fibers — at the muscovite mica‐water interface is explored using in situ AFM. Abstract Protein adsorption at solid–liquid interfaces underlies many biomedical and materials
Chenyang Shi +7 more
wiley +1 more source
Systematic Review of Plant Ribosome Heterogeneity and Specialization
Frontiers in Plant Science, 2020 Plants dedicate a high amount of energy and resources to the production of ribosomes. Historically, these multi-protein ribosome complexes have been considered static protein synthesis machines that are not subject to extensive regulation but only read ...
Federico Martínez-Seidel +3 more
semanticscholar +1 more source
Probiotic‐Based Materials as Living Therapeutics
Advanced Materials, EarlyView.Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio +2 more
wiley +1 more source
rRNA methyltransferases and their role in resistance to antibiotics [PDF]
Journal of Medical Biochemistry, 2010 Methyltransferases (MTases), a large protein superfamily, commonly use S-adenosyl-L-methionine (SAM) as the methyl group donor. SAM-dependant MTases methylate both nucleic acids (DNA, RNA) and proteins, and thus modulate their activity, function and ...
Morić Ivana +5 more
doaj
Dynamics of ribosomes and release factors during translation termination in E. coli
eLife, 2018 Release factors RF1 and RF2 promote hydrolysis of peptidyl-tRNA during translation termination. The GTPase RF3 promotes recycling of RF1 and RF2. Using single molecule FRET and biochemical assays, we show that ribosome termination complexes that carry ...
Sarah Adio +8 more
doaj +1 more source