Results 131 to 140 of about 358,575 (311)
The Plant Cell, 2019 The functional organization of ribosomal DNA and ribosome assembly in plants is described, along with recent findings concerning a plant-specific mechanism involved in ribosome stress responses.
J. Sáez-Vásquez, M. Delseny
semanticscholar +1 more source
Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria
Nature, 2022 Kazuki Saito +9 more
semanticscholar +1 more source
Regulation of Ribosome Biogenesis in Skeletal Muscle Hypertrophy.
Physiology, 2019 The ribosome is the enzymatic macromolecular machine responsible for protein synthesis. The rates of protein synthesis are primarily dependent on translational efficiency and capacity. Ribosome biogenesis has emerged as an important regulator of skeletal
V. Figueiredo, J. McCarthy
semanticscholar +1 more source
Slowing translation to avoid ribosome population extinction and maintain stable allocation at slow growth rates [PDF]
arXivTo double the cellular population of ribosomes, a fraction of the active ribosomes is allocated to synthesize ribosomal proteins. Subsequently, these ribosomal proteins enter the ribosome self-assembly process, synthesizing new ribosomes and forming the well-known ribosome autocatalytic subcycle.
arxiv
Mass spectrometry and ribosome profiling, a perfect combination towards a more comprehensive identification strategy of true in vivo protein forms [PDF]
, 2013 An increasing number of studies involve integrative analysis of gene and protein expression data, taking advantage of new technologies such as next-generation transcriptome sequencing (RNA-Seq) and highly sensitive mass spectrometry (MS).
Crappé, Jeroen +5 more
core
Ubiquitination of stalled ribosome triggers ribosome-associated quality control
Nature Communications, 2017 Translation arrest by polybasic sequences induces ribosome stalling, and the arrest product is degraded by the ribosome-mediated quality control (RQC) system. Here we report that ubiquitination of the 40S ribosomal protein uS10 by the E3 ubiquitin ligase
Y. Matsuo +12 more
semanticscholar +1 more source
Ribosome pausing, a dangerous necessity for co-translational events
Nucleic Acids Research, 2019 In recent years translation elongation has emerged as an important contributor to the regulation of gene expression. There are multiple quality control checkpoints along the way of producing mature proteins and targeting them to the right cellular ...
M. Collart, Benjamin Weiss
semanticscholar +1 more source
Antibiotic resistance evolved via inactivation of a ribosomal RNA methylating enzyme. [PDF]
, 2016 Modifications of the bacterial ribosome regulate the function of the ribosome and modulate its susceptibility to antibiotics. By modifying a highly conserved adenosine A2503 in 23S rRNA, methylating enzyme Cfr confers resistance to a range of ribosome ...
Fujimori, Danica Galonić +3 more
core
eLife, 2017 The eukaryotic pre-initiation complex (PIC) bearing the eIF2·GTP·Met-tRNAiMet ternary complex (TC) scans the mRNA for an AUG codon in favorable context.
Jyothsna Visweswaraiah +1 more
doaj +1 more source