Results 141 to 150 of about 406,930 (327)
eLife, 2018 In eukaryotic translation initiation, AUG recognition of the mRNA requires accommodation of Met-tRNAi in a ‘PIN’ state, which is antagonized by the factor eIF1.
Jose Luis Llácer +9 more
doaj +1 more source
BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43
Advanced Science, EarlyView.This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan +13 more
wiley +1 more source
Evaluation of promoters and ribosome binding sites for biotechnological applications in the unicellular cyanobacterium Synechocystis sp. PCC 6803 [PDF]
, 2016 Elias Englund +2 more
openalex +1 more source
Regulation of Ribosome Biogenesis in Skeletal Muscle Hypertrophy.
Physiology, 2019 The ribosome is the enzymatic macromolecular machine responsible for protein synthesis. The rates of protein synthesis are primarily dependent on translational efficiency and capacity. Ribosome biogenesis has emerged as an important regulator of skeletal
V. Figueiredo, J. McCarthy
semanticscholar +1 more source
Advanced Science, EarlyView.Editing susceptibility lncRNAs offers a strategy to enhance disease resistance without yield loss. RESIS, a domestication‐acquired, pathogen‐induced lncRNA, promotes protein N‐terminal acetylation through its interaction with NatA complex. Knockout of RESIS increases translation and confers broad‐spectrum resistance to both fungal and bacterial ...
Wen‐long Zhao +17 more
wiley +1 more source
Initial Steps in RNA Processing and Ribosome Assembly Occur at Mitochondrial DNA Nucleoids [PDF]
, 2014 Daniel Bogenhagen +2 more
openalex +1 more source
Advanced Science, EarlyView.Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu +6 more
wiley +1 more source
Ribosome Reinitiation Directs Gene-specific Translation and Regulates the Integrated Stress Response [PDF]
, 2015 Sara K. Young +4 more
openalex +1 more source
Advanced Science, EarlyView.tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan +10 more
wiley +1 more source