Results 171 to 180 of about 406,930 (327)

Soil Nutrient Enrichment Induces Trade‐Offs in Bacterial Life‐History Strategies Promoting Plant Productivity

open access: yesAdvanced Science, EarlyView.
Soil nutrient enrichment induces the trade‐offs between bacterial functional potential and growth‐rate potential. Such trade‐offs favor specific plant‐beneficial species and genes, playing a pivotal role in determining plant productivity. These findings enhance the understanding of the microbial responses in agroecosystems to ongoing global ...
Yuanyuan Yan   +5 more
wiley   +1 more source

RiboProP: a probabilistic ribosome positioning algorithm for ribosome profiling [PDF]

open access: bronze, 2018
Dengke Zhao   +3 more
openalex   +1 more source

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

open access: yesAdvanced Science, EarlyView.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang   +14 more
wiley   +1 more source

An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene [PDF]

open access: green, 2021
Muhammad S. Azman   +7 more
openalex   +1 more source

The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1974
J. Shine, L. Dalgarno
semanticscholar   +1 more source

Ubc9‐Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9‐p16 Axis

open access: yesAdvanced Science, EarlyView.
Liver aging is characterized by a decline in the expression of the SUMO‐conjugating enzyme Ubc9, resulting in reduced SUMOylation levels in hepatocytes, particularly in the case of ribosomal protein RPL3. Disruption of RPL3 SUMOylation increases its nuclear translocation. Interestingly, ribosome‐free RPL3 facilitates the recruitment of helicase DHX9 to
Hao Xie   +22 more
wiley   +1 more source

LSTrAP-Crowd: Prediction of novel components of bacterial ribosomes with crowd-sourced analysis of RNA sequencing data [PDF]

open access: green, 2020
Benedict Hew   +99 more
openalex   +1 more source

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

open access: yesAdvanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li   +13 more
wiley   +1 more source

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