Results 171 to 180 of about 343,033 (331)
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han +16 more
wiley +1 more source
Protein Sculpting: Probing the Interplay between the Ribosome and Molecular Chaperones in Protein Folding in the Cell [PDF]
Rayna M. Addabbo +4 more
openalex +1 more source
An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene [PDF]
Muhammad S. Azman +7 more
openalex +1 more source
L, Gorini, G A, Jacoby, L, Breckenridge
openaire +2 more sources
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao +14 more
wiley +1 more source
The ribosome quality control factors Asc1 and Hel2 regulate the expression of HSP70 during heat shock and recovery [PDF]
Lokha R. Alagar Boopathy +6 more
openalex +1 more source
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu +8 more
wiley +1 more source
Editorial: Bacterial Mechanisms of Antibiotic Resistance: A Structural Perspective
Graeme L. Conn +2 more
doaj +1 more source

