Results 171 to 180 of about 343,033 (331)

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

open access: yesAdvanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han   +16 more
wiley   +1 more source

Protein Sculpting: Probing the Interplay between the Ribosome and Molecular Chaperones in Protein Folding in the Cell [PDF]

open access: bronze, 2017
Rayna M. Addabbo   +4 more
openalex   +1 more source

An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene [PDF]

open access: green, 2021
Muhammad S. Azman   +7 more
openalex   +1 more source

Ribosomal Ambiguity

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1966
L, Gorini, G A, Jacoby, L, Breckenridge
openaire   +2 more sources

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

The ribosome quality control factors Asc1 and Hel2 regulate the expression of HSP70 during heat shock and recovery [PDF]

open access: green, 2022
Lokha R. Alagar Boopathy   +6 more
openalex   +1 more source

Bacterial Ribosome

open access: yesBacteriological Reviews, 1970
openaire   +2 more sources

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu   +8 more
wiley   +1 more source

Editorial: Bacterial Mechanisms of Antibiotic Resistance: A Structural Perspective

open access: yesFrontiers in Molecular Biosciences, 2019
Graeme L. Conn   +2 more
doaj   +1 more source

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