Results 201 to 210 of about 406,930 (327)

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

Advanced Science, EarlyView.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang, Jie‐Mei Zhao, Chuan‐Yu Xiang, Yi‐Wen Ma, Hong‐Peng Lei, Yu‐Ying Shi, Shun Zhou, Xiaofei Zeng, Jinsong Chen, Fei Liu, Benhe Zeng, Rui Song, Ye Hu, Feng Zhang, Xiang Liu, Wen‐Xiang Li, Gui‐Tang Wang, Ivan Jakovlić   +17 more
wiley   +1 more source

Structural insights into context-specific inhibition of bacterial translation by macrolides. [PDF]

Nat Commun
Syroegin EA, Aleksandrova EV, Kruglov AA, Paranjpe MN, Svetlov MS, Polikanov YS.   +5 more
europepmc   +1 more source

Factor-Independent Assembly of Elongation-Competent Ribosomes by an Internal Ribosome Entry Site Located in an RNA Virus That Infects Penaeid Shrimp

, 2004
Randal C. Cevallos, Peter Sarnow
openalex   +1 more source

A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation [PDF]

, 2015
Alexander P. Fields, Edwin Rodriguez, Marko Jovanović, Noam Stern‐Ginossar, Brian J. Haas, Philipp Mertins, Raktima Raychowdhury, Nir Hacohen, Steven A. Carr, Nicholas T. Ingolia, Aviv Regev, Jonathan S. Weissman   +11 more
openalex   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis [PDF]

, 2017
Kailu Yang, Jeng-Yih Chang, Zhicheng Cui, Xiaojun Li, Ran Meng, Li‐Jun Duan, Jirapat Thongchol, Joanita Jakana, Christoph M. Huwe, James C. Sacchettini, Junjie Zhang   +10 more
openalex   +1 more source

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

Advanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li, Chen Guo, Xiaoli Wu, Cuiting Wu, Songfen Wu, Si Su, Min Wu, Xidan Zhou, Si Li, Yihui Cui, Tao Zhou   +10 more
wiley   +1 more source

Genomic and translational insights into eIF2B-mediated salt tolerance in sea rice HD961. [PDF]

BMC Biol
Chen H, Chen M, Yang S, Zhou H, Xie Z, Huang Y, Chen D.   +6 more
europepmc   +1 more source

Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function [PDF]

, 2010
Hasan DeMi̇rci̇, F.V. Murphy, Riccardo Belardinelli, Ann C. Kelley, V. Ramakrishnan, Steven T. Gregory, Albert E. Dahĺberg, G. Jogl   +7 more
openalex   +1 more source

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

Science, 2018
Gregory A. Wyant, Monther Abu-Remaileh, Evgeni M. Frenkel, N. N. Laqtom, Vimisha Dharamdasani, C. Lewis, Sze Ham Chan, I. Heinze, A. Ori, D. Sabatini   +9 more
semanticscholar   +1 more source