Results 211 to 220 of about 406,930 (327)

Engineering Metal‐Organic‐Framework‐Based STING Nanoagonists for PROTAC‐Enhanced Cancer Chemo‐Metalloimmunotherapy

Advanced Science, EarlyView.
Schematic overview of PROTAC‐enhanced chemo‐metalloimmunotherapy, integrating senescence induction, multi‐modal STING pathway activation, PD‐L1 blockade, and immune amplification via coordinated PROTACs, metal ions, and chemotherapy to elicit robust antitumor immunity and circumvent immune evasion.
Zhenzhen Chen, Zhe Feng, Siyuan Wang, Jingjing Zhang   +3 more
wiley   +1 more source

From denaturant to ribosome: rethinking chaperone requirements in cells

Yevheniia Bushman, Andrew W. Truman
openalex   +1 more source

NUDT21‐mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression

Advanced Science, EarlyView.
NUDT21 is overexpressed in colorectal cancer tumors and promotes colorectal cancer progression. NUDT21 promotes the production of a cyclin‐dependent kinase 19 (CDK19) mRNA isoform with a long 3′ UTR, which enhances cytoplasmic export and translation. Truncation of the CDK19 long 3′ UTR phenocopies NUDT21 loss, recapitulating the defects in cholesterol ...
Yeping Yu, Jixin Ma, Minwei Zhou, Xiaodong Gu, Yiming Zhou, Zhenyang Li, Tianyu Zhang, Wei Gong, Chuanxin Huang, Jianbin Xiang   +9 more
wiley   +1 more source

Chromosome duplication causes premature aging via defects in ribosome quality control. [PDF]

PLoS Biol
Escalante LE, Hose J, Ahrens JM, Howe H, Paulsen N, Liss SJ, Place M, Gasch AP.   +7 more
europepmc   +1 more source

Peer Review #2 of "Differential scanning calorimetry of whole Escherichia coli treated with the antimicrobial peptide MSI-78 indicate a multi-hit mechanism with ribosomes as a novel target (v0.1)"

, 2015
Alexander C. Brannan, William Whelan, Emma Cole, Valerie Booth   +3 more
openalex   +2 more sources

Supplementary Materials S1 from BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma

, 2023
Keiji Kurata, Mehmet Samur, Priscilla Liow, Kenneth Wen, Leona Yamamoto, Jiye Liu, Eugenio Morelli, Annamaria Gullà, Yu‐Tzu Tai, Jun Qi, Teru Hideshima, Kenneth C. Anderson   +11 more
openalex   +1 more source

Selective translation by alternative bacterial ribosomes [PDF]

, 2020
Yuxiang Chen, Zhiyu Xu, Xueliang Ge, Jia-Yao Hong, Suparna Sanyal, Zhi John Lu, Babak Javid   +6 more
openalex   +1 more source

Crystal Structure of the Ribosome at 5.5 Å Resolution

Science, 2001
M. Yusupov, G. Yusupova, A. Baucom, K. Lieberman, T. Earnest, J. Cate, H. Noller   +6 more
semanticscholar   +1 more source

Bacterial DNA‐Targeting AIE Photosensitizer for Efficient Eradication of Intracellular Bacteria and Biofilm‐Associated Infections

Aggregate, EarlyView.
A bacterial DNA‐targeted PS TPE‐CN for the precise treatment of MRSA‐associated infections has been developed. Through synergistic PDT effect, TPE‐CN damages bacterial DNA and membrane, resulting in effective elimination of planktonic bacteria, biofilm, and intracellular bacteria.
Yonghui Lv, Minyang Zhao, Qiaowen Lin, Zhiwen Xu, Qingqing Bai, Dan Ding, Duo Mao, Kang‐Nan Wang   +7 more
wiley   +1 more source

Establishment of an imaging-based screening pipeline for the identification of human ribosome biogenesis inhibitors. [PDF]

BMC Biol
Gafko C, Hollandi R, Dörner K, Rosellini M, Zemp I, Horvath P, Kutay U.   +6 more
europepmc   +1 more source