Results 241 to 250 of about 176,411 (317)

Quantifying Soil Microbiome Abundance by Metatranscriptomics and Complementary Molecular Techniques—Cross‐Validation and Perspectives

Molecular Ecology Resources, EarlyView.
ABSTRACT Linking meta‐omics and biogeochemistry approaches in soils has remained challenging. This study evaluates the use of an internal RNA extraction standard and its potential for making quantitative estimates of a given microbial community size (biomass) in soil metatranscriptomics. We evaluate commonly used laboratory protocols for RNA processing,
Mathilde Borg Dahl, Stella Brachmann, Andrea Söllinger, Marina Schnell, Laureen Ahlers, Magdalena Wutkowska, Katharina J. Hoff, Neetika Nath, Verena Groß, Haitao Wang, Micha Weil, Marc Piecha, Marc Schaffer, Corinna Jensen, Andreas W. Kuss, Christoph Gall, Erika Wimmer, Thomas Pribasnig, Alexander Tøsdal Tveit, Bjarni D. Sigurdsson, Christa Schleper, Andreas Richter, Tim Urich   +22 more
wiley   +1 more source

The Central Role of Ribosomal Proteins in p53 Regulation. [PDF]

Cancers (Basel)
Lindström MS.
europepmc   +1 more source

Mitochondrial ribosomes

Horizons in biochemistry and biophysics, 1977
openaire   +3 more sources

Enrichment of Helminth Mitochondrial Genomes From Faecal Samples Using Hybridisation Capture

Molecular Ecology Resources, EarlyView.
ABSTRACT New approaches are urgently needed to enrich rare or low‐abundant DNA in complex samples. Soil‐transmitted helminths (STHs) inhabit heterogeneous environments, including the gastrointestinal tract of their host as adults and are excreted as eggs and larvae in faeces, complicating our understanding of their biology and the use of genetic tools ...
Marina Papaiakovou, Andrea Waeschenbach, Roy M. Anderson, Piet Cools, Zeleke Mekonnen, D. Timothy J. Littlewood, Cinzia Cantacessi, Stephen R. Doyle   +7 more
wiley   +1 more source

In Vivo Ribosome-Amplified MetaBOlism, RAMBO, Effect Observed by Real Time Pulse Chase, RTPC, NMR Spectroscopy. [PDF]

Biochemistry
Yu J, Sciolino N, Breindel L, Lin Q, Burz DS, Shekhtman A.   +5 more
europepmc   +1 more source

Short‐Term Severe Energy Restriction Promotes Molecular Health and Reverses Aging Signatures in Adults With Prediabetes in the PREVIEW Study

Aging Cell, EarlyView.
Severe short‐term energy restriction in adults with prediabetes led to a significant reduction in circulating proteins linked to inflammation, senescence, and protein turnover. These changes, partly mediated by extracellular vesicles, suggest systemic dietary‐induced benefits beyond glycemic control, including improved aging biomarkers.
Maria Lastra Cagigas, Andrius Masedunskas, Yao Lin, Samantha J. Emery‐Corbin, Jumana M. Yousef, Laura F. Dagley, Sam Olechnowicz, Rory Bowden, Rachael Hayward, Gary Low, Roslyn Muirhead, Jennie Brand‐Miller, Mikael Fogeltholm, Anne Raben, Marco Demaria, Stephen J. Fuller, Luigi Fontana   +16 more
wiley   +1 more source

Mechanism of nascent chain removal by the ribosome-associated quality control complex. [PDF]

Nat Commun
Li W, Scheel T, Shen PS.
europepmc   +1 more source

Integrative Multiparametric Analysis of Circulating Cell‐Free Nucleic Acids of Plasma in Healthy Individuals During Aging

Aging Cell, EarlyView.
We performed the first integrative multiparametric analysis of plasma circulating cell‐free nucleic acids, including nuclear and mitochondrial DNA, as well as ribosomal, messenger, and micro‐RNAs, in a cohort of 139 healthy individuals. We focused on quantity, integrity, and DNA methylation using assays targeting highly repetitive DNA and highly ...
Nicolas P. Tessier, Lise M. Hardy, Florence Mauger, Antoine Daunay, Christian Daviaud, Ilef Hchaichi, Caroline Horgues, Mourad Sahbatou, Hélène Le Buanec, Jean‐François Deleuze, Alexandre How‐Kit   +10 more
wiley   +1 more source

Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering. [PDF]

RNA
De S, Zhou M, Brown ZP, Burton-Smith RN, Hashem Y, Pestova TV, Hellen CUT, Frank J.   +7 more
europepmc   +1 more source

Chronic Cellular NAD Depletion Activates a Viral Infection‐Like Interferon Response Through Mitochondrial DNA Leakage

Aging Cell, EarlyView.
Chronic NAD depletion in fibroblasts lowers NAD levels, increases mitochondrial mass, and triggers an interferon‐dependent inflammatory response via mtDNA leakage through VDAC1, activating the cGAS‐STING pathway. This links NAD deficiency to metabolic and inflammatory processes, with implications for diseases associated with NAD decline.
Claudia C. S. Chini, Laura Colman, Eduardo Palmieri, Jessica L. Strange, Sonu Kashyap, Bing Han, Andres Benitez‐Rosendo, Gina L. Ciccio Lopez, Sara Peixoto Rabelo, Shreyartha Mukherjee, Gustavo H. de Souza, John Varga, Ralph G. Meyer, Mirella L. Meyer‐Ficca, Eduardo N. Chini   +14 more
wiley   +1 more source