Results 261 to 270 of about 173,360 (283)

Mitochondrial ribosome biogenesis and redox sensing. [PDF]

FEBS Open Bio
Brischigliaro M, Sierra-Magro A, Ahn A, Barrientos A.   +3 more
europepmc   +1 more source

Integrative Transcriptomic and Phosphoproteomic Analysis Reveals Key Components of the SnRK1 Signaling Network in Rice

Plant Direct, Volume 9, Issue 11, November 2025.
ABSTRACT SnRK1 is an evolutionarily conserved protein kinase belonging to the SNF1/AMPK family of protein kinases that is central to adjusting growth in response to the energy status. Numerous studies have shown adaptive and developmental roles of SnRK1, but the understanding of the SnRK1 signaling network in monocots is limited.
Maria C. Faria‐Bates, Chandan Maurya, K. Muhammed Jamsheer, Vibha Srivastava   +3 more
wiley   +1 more source

Polysome profiling is an extensible tool for the analysis of bulk protein synthesis, ribosome biogenesis, and the specific steps in translation. [PDF]

Mol Biol Cell
Rodriguez-Martinez A, Young-Baird SK.
europepmc   +1 more source

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

PROTEOMICS, Volume 25, Issue 21-22, Page 102-150, November 2025.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam, Krishna Kumar Tiwari, Luana Licata, Simona Panni, Sylvie Ricard‐Blum, Sucharitha Balu, Susie Huget, Juan Jose Medina Reyes, Eliot Ragueneau, Livia Perfetto, Birgit Meldal, Sandra Orchard, Henning Hermjakob   +12 more
wiley   +1 more source

Effect of aberrant ribosome biogenesis on wild-type and mutant p53 in cancer cells

, 2014
Marco Dal Ferro
openalex   +1 more source

Proteomics Insights Into Lysosome Biogenesis and Maturation

PROTEOMICS, Volume 25, Issue 21-22, Page 6-24, November 2025.
ABSTRACT Lysosomes constitute the main degradative organelle of most eukaryotic cells and are capable of breaking down a wide spectrum of biomolecules, including proteins, lipids, glycans, and DNA/RNA. They play crucial roles in the regulation of cellular homeostasis, acting as metabolic signaling centers for the correlation of nutrient availability ...
Katharina Hirn, Sofía Fajardo‐Callejón, Dominic Winter   +2 more
wiley   +1 more source

Structural insights into SARS‐CoV‐2 nonstructural protein 4 (nsp4) biogenesis

Protein Science, Volume 34, Issue 11, November 2025.
Abstract The SARS‐CoV‐2 virus—responsible for the COVID‐19 pandemic—requires a replication–transcription complex (RTC) for efficient RNA synthesis and viral propagation. One critical RTC component is nonstructural protein 4 (nsp4), a multipass transmembrane (TM) protein implicated in endoplasmic reticulum (ER) membrane rearrangements and double ...
José M. Acosta‐Cáceres, Fabio Lolicato, Laura Gadea‐Salom, Juan Ortiz‐Mateu, Diego Belda, Luis Martínez‐Gil, María Jesús García‐Murria, Ismael Mingarro   +7 more
wiley   +1 more source

Nanoscale Analysis beyond Imaging by Atomic Force Microscopy: Molecular Perspectives on Oncology and Neurodegeneration

Small Science, Volume 5, Issue 11, November 2025.
Cancer and neurodegeneration share interconnected nanosized molecular pathways. Novel nanobiomedicine approaches promise targeted biomarkers and therapies. Atomic force microscopy (AFM) is invaluable to characterize nanosized biomolecular processes beyond imaging.
Carlos Marcuello, KeeSiang Lim, Giacomo Nisini, Vadim S. Pokrovsky, João Conde, Francesco Simone Ruggeri   +5 more
wiley   +1 more source

Correction: BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma. [PDF]

Clin Cancer Res
Kurata K, Samur MK, Liow P, Wen K, Yamamoto L, Liu J, Morelli E, Gulla A, Tai YT, Qi J, Hideshima T, Anderson KC.   +11 more
europepmc   +1 more source

Mixed Messages: Dynamic and Compositional Heterogeneity of Nuclear Messenger Ribonucleoprotein (mRNP) Complexes

WIREs RNA, Volume 16, Issue 6, November/December 2025.
RNA‐protein (RNP) complexes formed by a network of RNA–RNA, RNA–protein, and protein–protein interactions are central to gene expression. mRNP compositional heterogeneity underlies precise regulation (e.g., export, storage, translation, and decay), enabling cells to adapt to changing conditions, with changes in composition further linked to stress ...
Theresa Wechsler, Ryuta Asada, Ben Montpetit   +2 more
wiley   +1 more source