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Ribosome biogenesis in plants requires the nuclear envelope and mitochondria localized OPENER complex. [PDF]
Nat CommunWang W +5 more
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Ribosome biogenesis and cancer
Acta Histochemica, 2017 There is growing evidence indicating that the human pathological conditions characterized by an up-regulated ribosome biogenesis are at an increased risk of cancer onset. At the basis of this relationship is the close interconnection between the ribosome
Lorenzo Montanaro +2 more
exaly +4 more sources
Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]
International Journal of Molecular Sciences, 2021 Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis. Mitochondrial ribosomes (mitoribosomes) perform translation of the proteins essential for the oxidative phosphorylation system. The biogenesis of cytoribosomes and
Annapina Russo
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The homeostatic regulation of ribosome biogenesis
Seminars in Cell & Developmental Biology, 2023The continued integrity of biological systems depends on a balance between interdependent elements at the molecular, cellular, and organismal levels. This is particularly true for the generation of ribosomes, which influence almost every aspect of cell and organismal biology.
Chunyang, Ni, Michael, Buszczak
openaire +2 more sources
Ribosome biogenesis: An emerging druggable pathway for cancer therapeutics [PDF]
Biochemical Pharmacology, 2019 Ribosomes are nanomachines essential for protein production in all living cells. Ribosome synthesis increases in cancer cells to cope with a rise in protein synthesis and sustain unrestricted growth.
Denis Lafontaine +2 more
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Bioinformatics and Biology Insights, 2015 Ribosome biogenesis involves a large inventory of proteinaceous and RNA cofactors. More than 250 ribosome biogenesis factors (RBFs) have been described in yeast.
Sotirios Fragkostefanakis +2 more
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Chloroplast Ribosome Biogenesis Factors
Plant And Cell Physiology, 2023Abstract The formation of chloroplasts can be traced back to an ancient event in which a eukaryotic host cell containing mitochondria ingested a cyanobacterium. Since then, chloroplasts have retained many characteristics of their bacterial ancestor, including their transcription and translation machinery.
Lisa-Marie Schmid +3 more
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1991
Publisher Summary This chapter focuses on the concept of ribosome biogenesis in yeast. The formation of functional ribosomes is a highly complex phenomenon requiring the interplay of a large number of molecular processes. Ribosomes contain, depending on their origin, some 60–80 different components, proteins, and RNA molecules, most in a single copy ...
H A, Raué, R J, Planta
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Publisher Summary This chapter focuses on the concept of ribosome biogenesis in yeast. The formation of functional ribosomes is a highly complex phenomenon requiring the interplay of a large number of molecular processes. Ribosomes contain, depending on their origin, some 60–80 different components, proteins, and RNA molecules, most in a single copy ...
H A, Raué, R J, Planta
openaire +2 more sources
Ribosome biogenesis in cancer: new players and therapeutic avenues
Nature Reviews Cancer, 2017 The ribosome is a complex molecular machine composed of numerous distinct proteins and nucleic acids and is responsible for protein synthesis in every living cell.
Joffrey Pelletier, Sinisa Volarevic
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Control of ribosome biogenesis in yeast
Trends in Genetics, 1988Abstract Ribosome formation in eukaryotes requires the coordinate expression of the genes for about 80 different RNA and protein components. These genes are widely dispersed over the genome, are present in various multiplicities and are transcribed by three different RNA polymerases.
R J, Planta, H A, Raué
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