Results 241 to 250 of about 142,894 (282)

Ubiquitination of Oncogenic Mutant p53 via Attenuation of Ribosome Biogenesis Machinery Effectively Inhibits Pancreatic Tumor Growth. [PDF]

Mol Cancer Ther
Ahmad M, Alvi SS, Ahsan H, Perez C, Massey A, Kashyap VK, Chauhan N, Anning E, Tripathi MK, Kim DJ, Sahoo N, Oraby T, Yallapu MM, Khan MM, Sebastian MM, Chauhan SC, Hafeez BB.   +16 more
europepmc   +1 more source

The Nucleolus: A Central Hub for Ribosome Biogenesis and Cellular Regulatory Signals. [PDF]

Int J Mol Sci
Ponti D.
europepmc   +1 more source

Altered Expression of Ribosome Biogenesis Regulators (TP53, C-MYC, FBL, and NCL) in Precursor B-cell Acute Lymphoblastic Leukemia and Neuroblastoma. [PDF]

Curr Issues Mol Biol
Horochowska M, Przystupski D, Kamińska M, Bil-Lula I, Kazanowska B, Ussowicz M.   +5 more
europepmc   +1 more source

Domostegui A, Peddigari S, Mercer CA, et al. Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death. Blood. 2021;137(24):3351-3364.

Blood
europepmc   +1 more source

Ribosome biogenesis and cancer

Acta Histochemica, 2017
There is growing evidence indicating that the human pathological conditions characterized by an up-regulated ribosome biogenesis are at an increased risk of cancer onset. At the basis of this relationship is the close interconnection between the ribosome
Lorenzo Montanaro, Davide Trere', Massimo Derenzini   +2 more
exaly   +4 more sources

Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]

International Journal of Molecular Sciences, 2021
Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis. Mitochondrial ribosomes (mitoribosomes) perform translation of the proteins essential for the oxidative phosphorylation system. The biogenesis of cytoribosomes and
Annapina Russo
exaly   +4 more sources

snoRNPs: Functions in Ribosome Biogenesis [PDF]

Biomolecules, 2020
Ribosomes are perhaps the most critical macromolecular machine as they are tasked with carrying out protein synthesis in cells. They are incredibly complex structures composed of protein components and heavily chemically modified RNAs. The task of assembling mature ribosomes from their component parts consumes a massive amount of energy and requires ...
Shawn Lyons, Sandeep Ojha, Lyons Shawn M   +2 more
exaly   +4 more sources

Some of the next articles are maybe not open access.

Related searches:

The homeostatic regulation of ribosome biogenesis

Seminars in Cell & Developmental Biology, 2023
The continued integrity of biological systems depends on a balance between interdependent elements at the molecular, cellular, and organismal levels. This is particularly true for the generation of ribosomes, which influence almost every aspect of cell and organismal biology.
Chunyang, Ni, Michael, Buszczak
openaire   +2 more sources

Ribosome biogenesis: An emerging druggable pathway for cancer therapeutics [PDF]

Biochemical Pharmacology, 2019
Ribosomes are nanomachines essential for protein production in all living cells. Ribosome synthesis increases in cancer cells to cope with a rise in protein synthesis and sustain unrestricted growth.
Denis L J Lafontaine, Frédéric Catez, Christiane Zorbas   +2 more
exaly   +2 more sources

Chloroplast Ribosome Biogenesis Factors

Plant And Cell Physiology, 2023
Abstract The formation of chloroplasts can be traced back to an ancient event in which a eukaryotic host cell containing mitochondria ingested a cyanobacterium. Since then, chloroplasts have retained many characteristics of their bacterial ancestor, including their transcription and translation machinery.
Lisa-Marie Schmid, Nikolay Manavski, Wei Chi, Jörg Meurer   +3 more
openaire   +2 more sources