Results 221 to 230 of about 142,894 (282)

Targeted Metabolomics Reveals Tissue‐Specific Accumulation and Translocation of Bioactive Compounds in Ginger During Growth

Food Frontiers, Volume 7, Issue 5, September 2026.
Targeted UHPLC–MS/MS methods were established to quantify 32 bioactive compounds in ginger leaves, stems, and rhizomes during growth. Distinct tissue‐specific accumulation and translocation patterns were observed, and aminoacyl‐tRNA biosynthesis was identified as the most active pathway in ginger development.
Yinfeng Zhao, Qin Wang, Jiguang Zhang, Xiuhua Liu, Yixuan Jiang, Qingzhi Li, Chunhua Shang, Min Lin, Rui Weng, Jing Qiu, Yongzhong Qian   +10 more
wiley   +1 more source

Possible role of ribosome biogenesis in the recovery from transient hepatic damage caused by ethylene glycol in rats. [PDF]

Forensic Toxicol
Unuma K, Aki T, Kobayashi N, Isa S, Tojo A.   +4 more
europepmc   +1 more source

Engineering Piezo1‐Mediated Calcium Signalling for Enhanced Extracellular Vesicle Biogenesis and Cargo Loading

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Cell‐derived extracellular vesicles (EVs) are promising nanocarriers for therapeutic delivery platforms owing to their biocompatibility and capacity to protect and efficiently transport bioactive molecules. However, EV‐based therapeutics remain constrained by inefficient cargo loading and low production yields, which limit scalable ...
Najla A. Saleh, Rozita Shafiq, Amanda P. Cicerone, Sadhana Kilangodi, Hayden Hartwig, George I. Mias, Guangqing Lu, Jun R. Huh, Weiping Li, Cheri X. Deng, Masamitsu Kanada   +10 more
wiley   +1 more source

Mitochondrial CLPP in Health and Disease: Mechanisms, Therapeutic Duality and Emerging Opportunities

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
The graphical abstract illustrates the context‐dependent therapeutic modulation of CLPP. Pharmacological CLPP activation has reached clinical application in cancer (black arrow), whereas reduced CLPP activity has shown beneficial effects experimentally in models of primary mitochondrial disease and metabolic syndrome, as well as cancer (grey arrows ...
Lea Isermann, Aleksandra Trifunovic
wiley   +1 more source

Guanine nucleotides drive ribosome biogenesis and glycolytic reprogramming in acute myeloid leukemia stem cells.

Blood
Kawano G, Ikeda R, Ishihara D, Shima T, Sakoda T, Yamamoto S, Kochi Y, Semba Y, Ashitani S, Mori Y, Kato K, Maeda T, Miyamoto T, Soga T, Akashi K, Kikushige Y.   +15 more
europepmc   +1 more source

Inter‐tissue relationships of gene expression in liver, muscle and adipose tissue of children with end‐stage chronic liver disease

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 3, Page 500-508, September 2026.
Abstract Objectives End‐stage chronic liver disease in children is associated with sarcopenia and aberrant adipose tissue mass. We investigated correlations between liver pathology‐associated gene pathways (fibrosis, inflammation and steatosis) and metabolic genes in muscle and adipose tissue.
Eirini Kyrana, Cheng Zhang, Han Jin, Siamak Salehi, Jonathan C. K. Wells, Maesha Deheragoda, Ragai R. Mitry, Anil Dhawan   +7 more
wiley   +1 more source

Mitochondria as the Hub of Apoptosis: A Comprehensive Insight From Mitochondria to Interactions With Other Organelles

MedComm, Volume 7, Issue 9, September 2026.
Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan, Jinming Zhao, Rong Wang, Yue Shi, Zaozao Chen, Yixuan Ma, Na Li, Wenqing Duan, Duo Lin, Chunxiang Zhang   +9 more
wiley   +1 more source

TMEM105 upregulation promotes colorectal cancer malignancy: a novel prognostic biomarker potentially linked to the MYC-Ribosome biogenesis axis. [PDF]

Cancer Cell Int
Rezaenasab A, Zargar SJ, Peymani M, Ghaedi K.   +3 more
europepmc   +1 more source

The Health Benefits of Exercise: Molecular and Cellular Mechanisms

MedComm, Volume 7, Issue 9, September 2026.
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying, Huilin Wang, Xiu Lu, Wenjuan Zhang, Zhehao Lin, Kai Wang, Shangxuan Li, Lu Chen, Mingchao Jiang, Sarkawt Hamad, Yi Wang, Jianmin Wu, Shukuan Ling   +12 more
wiley   +1 more source

Ribosome biogenesis in plants requires the nuclear envelope and mitochondria localized OPENER complex. [PDF]

Nat Commun
Wang W, Mahboubi A, Zhu S, Hanson J, Mateus A, Niittylä T.   +5 more
europepmc   +1 more source