Results 201 to 210 of about 57,712 (282)

The role of USP36 in ribosome biogenesis and other pathophysiological processes. [PDF]

Front Mol Biosci
Shao L, Guo M, Kou Q, Guo Y, Li X, Li F.
europepmc   +1 more source

Fusion protein condensate formation via coiled‐coil domains

Protein Science, Volume 35, Issue 7, July 2026.
Abstract While recent research shows that biomolecular condensates play important roles in normal cellular processes and diseases, the driving forces in condensate formation are not well understood, especially regarding the role of structured self‐associative protein domains.
Om Prakash Narayan, Lu Liu, Kyle Scheller, Carter Humphrey, Jiawei Dong, Juan Guan   +5 more
wiley   +1 more source

Neuronal processes contain the essential components for the late steps of ribosome biogenesis. [PDF]

Proc Natl Acad Sci U S A
Fusco CM, Staab A, Bourke AM, Tushev G, Desch K, Lins EM, Ciirdaeva E, Tom Dieck S, Kaltenschnee N, Heckel A, Langer JD, Schuman EM.   +11 more
europepmc   +2 more sources

Ribosome Biogenesis and Function in Cancer: From Mechanisms to Therapy. [PDF]

Cancers (Basel)
Gitareja K, Chelliah SS, Sanij E, Sandhu S, Kang J, Khot A.   +5 more
europepmc   +1 more source

Co‐translational protein targeting to mitochondria in the context of co‐translational protein maturation

Protein Science, Volume 35, Issue 7, July 2026.
Abstract Mitochondria import the majority of their proteins from the cytosol, creating a fundamental challenge: precursor proteins must be synthesized, maintained in an import‐competent state, and delivered to mitochondrial translocases without premature folding or aggregation. While mitochondrial protein import has been considered a post‐translational
Nikita A. Kvasov, Yury S. Bykov
wiley   +1 more source

RATEX: A Scalable RNA‐Based Platform for Logical and Multi‐Layered Cellular Programming

Angewandte Chemie, Volume 138, Issue 26, 22 June 2026.
RATEX integrated ribosome‐mediated transcription control with synthetic RNA regulators, enabling simultaneous processing of RNA, metabolite, and small‐molecule inputs through complex logic operations within a single transcript. The platform achieves up to 1,492‐fold gene regulation, multi‐input hybrid logic gates, RNA‐programmed signaling cascades, and
Hyunseop Goh, Hansol Kang, Chaeri Kim, Jongmin Kim   +3 more
wiley   +2 more sources

Construction and verification of a prognostic model for prostate cancer based on ribosome biogenesis-related genes. [PDF]

BMC Med Genomics
Xie J, Tang Y, Wang Y, Gao X, Fu F, Liu Y, Yi C, Zhou G, Wang Z, Chen C, Jin P, Cai Y, Zhou J.   +12 more
europepmc   +1 more source

Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications

WIREs RNA, Volume 17, Issue 4, July/August 2026.
Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus, Shalon Suzanne Pinto, Sai Samanvitha Madagundapalli Ramakrishna, Dechamma Pandyanada Nanjappa, Gunimala Chakraborty, Anirban Chakraborty   +5 more
wiley   +1 more source

Establishment of an imaging-based screening pipeline for the identification of human ribosome biogenesis inhibitors. [PDF]

BMC Biol
Gafko C, Hollandi R, Dörner K, Rosellini M, Zemp I, Horvath P, Kutay U.   +6 more
europepmc   +1 more source

Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy

Aging Cell, Volume 25, Issue 7, July 2026.
Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang, Suyeon Choi, Soo‐Jin Kim, Sooyun Kim, Dong Hyun Jo, Tae Geol Lee, Kyu‐Sang Park, Jeong Hun Kim   +7 more
wiley   +1 more source