Results 191 to 200 of about 57,712 (282)
The function of Mak16 in ribosome biogenesis depends on its [4Fe-4S] cluster. [PDF]
Duppe N +7 more
europepmc +1 more source
A short‐term high‐carbohydrate diet enhances peripheral nerve regeneration more effectively than high‐protein or high‐fat diets by upregulating hemoglobin genes in Schwann cells. Increased hemoglobin promotes Schwann cell proliferation and migration, facilitating nerve repair.
Shiying Li +16 more
wiley +1 more source
RNase MRP subunit composition and role in 40S ribosome biogenesis. [PDF]
Smith EM, Ly J, Haug S, Cheeseman IM.
europepmc +1 more source
RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li +3 more
wiley +1 more source
Gatm ablation disrupts spermatogenesis by impairing ribosome biogenesis and coupling defective steroid biosynthesis to immunoglobulin silencing. [PDF]
Li S +5 more
europepmc +1 more source
Cross‐Level Regulatory Interactions Underlying Human Immune Aging
We performed multi‐omics sequencing on peripheral blood samples from 69 individuals aged 23–75 years and identified multi‐layered molecular interaction networks underlying the process of immune senescence, which provides a comprehensive multi‐omics framework for understanding immune aging and identifying potential strategies to delay immunosenescence ...
Quanyou Wu +9 more
wiley +1 more source
Redox signals and oxidative stress in the control of mitochondrial protein import
Abstract Mitochondrial protein import is essential for organelle biogenesis and cellular homeostasis. It operates in an environment that is intrinsically shaped by redox chemistry. Mitochondria are major sources of reactive oxygen species (ROS), which arise as by‐products of oxidative phosphorylation. Cells therefore maintain sophisticated ROS‐handling
Lidwina Hasberg +3 more
wiley +1 more source
A high-throughput screen for nucleolar function reveals a role for the signaling protein, SPRR3, in ribosome biogenesis. [PDF]
Sutton EC +4 more
europepmc +1 more source
Mass spectrometry proteomics for studying mitostasis
Abstract Maintaining mitochondrial integrity and function is fundamental to cellular homeostasis. Cells rely on coordinated protein quality control (QC) systems—including intricate chaperone‐protease networks, the ubiquitin‐proteasome system, and cytosolic surveillance pathways—that together form a dynamic, cell‐wide mitostasis network governing the ...
Lakshita Sharma +5 more
wiley +1 more source

