Results 231 to 240 of about 142,894 (282)

DUSP12 Regulates NAT10‐Mediated RNA Acetylation to Modulate DNA Repair and Therapeutic Response in Hepatocellular Carcinoma

MedComm, Volume 7, Issue 9, September 2026.
In hepatocellular carcinoma (HCC) cells exposed to doxorubicin, DUSP12 depletion maintains NAT10 phosphorylation, reducing its acetyltransferase activity, which leads to reduced ac4C RNA acetylation, DNA damage response, and DNA break repair, with consequent tumor sensitization.
Viktor Kalbermatter Boell, Diana Reis Della Corte Guimarães Pacheco, Yuli Thamires Magalhães, Laura Lima Turani, Isabeli Yumi Araújo Osawa, Nicolas Carlos Hoch, Fábio Luís Forti   +6 more
wiley   +1 more source

Correction to 'The cellular abundance of the essential transcription termination factor TTF-I regulates ribosome biogenesis and is determined by MDM2 ubiquitinylation'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia. [PDF]

Sci Adv
Li W, Zhao Y, Wu D, Chen Z, Qing Y, Yang F, Ji F, Zhang L, Sau L, Chen J, He C.   +10 more
europepmc   +1 more source

RNA‐Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
RNA‐binding proteins (RBPs) regulate RNA stability, localization, translation, and splicing through intrinsic binding domains and interactions with diverse cellular partners. Their competitive and cooperative networks shape disease‐related RNA programs, especially in cancer.
Ling Li, Xiuli Yan, Qing Ji, Hui Zhang
wiley   +1 more source

METTL7A‐Dependent m6A Methylation Orchestrates CXCR4hi Neutrophil Pathogenicity and NETosis in Skin Inflammation

MedComm, Volume 7, Issue 9, September 2026.
In psoriasis, METTL7A is upregulated in aged CXCR4hi neutrophils, where it stabilizes PLSCR1 mRNA via m6A modification to enhance reactive oxygen species (ROS) production and neutrophil extracellular trap (NET) formation, thereby exacerbating disease severity.
Wanting Liu, Jinkai Liang, Huiyi Quan, Xuan Liu, Kang Li, Xin Tang, Jiaqi Wang, Yunfeng Gu, Yaxing Bai, Ke Xue, Zhiguo Li, Xiaolei Su, Erle Dang, Jiaoling Chen, Gang Wang, Shuai Shao   +15 more
wiley   +1 more source

Transcription factor 25 modulates gametocytogenesis and ribosome biogenesis in the malaria parasite <i>Plasmodium falciparum</i>. [PDF]

Front Cell Infect Microbiol
Wu J, Zhang Z, Ngim C, Yang W, Li P, Wang F, Ye J, Li B, Tian B, Zhang Q, Shang X.   +10 more
europepmc   +1 more source

Transcriptomic stress responses in Vaccinium spp. F1 hybrids: Implications for temperature‐resilient cranberry breeding using a crop wild relative

PLANTS, PEOPLE, PLANET, Volume 8, Issue 5, Page 1715-1732, September 2026.
Climate extremes threaten the sustainability of cranberry production, a culturally and economically important North American crop. This study demonstrates that wild cranberries (Vaccinium oxycoccos) harbor genetic variation that may enhance cold stress resilience when introduced into cultivated cranberry through hybridization.
Audrey Dickinson, Jackson Kubal, Nicholas Allsing, Emily Murray, Todd P. Michael, James J. Polashock   +5 more
wiley   +1 more source

PTGER4 Governs Immune Evasion and Therapy Resistance in Kidney Cancer via Ribosome Biogenesis Dysregulation. [PDF]

J Cell Mol Med
Zhou H, Li Z, Ying J, Liu Y, Xu X, Huang J.   +5 more
europepmc   +1 more source

PCDHGB7 inhibits the progression of triple-negative breast cancer by suppressing XRCC5/MYC-mediated ribosome biogenesis. [PDF]

Clin Transl Med
Shan M, Bi H, Sun H, Li Y, Li Z, Wang Z, Dong J, Sang S, Ren L, Ye Y, Wang T, Volarević S, Su R, Zhang L, Zhang M, He Y, Zhang G, Li J, Li X.   +18 more
europepmc   +1 more source

Coupling of ribosome biogenesis and translation initiation in human mitochondria. [PDF]

Nat Commun
Heinrichs M, Finke AF, Aibara S, Krempler A, Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein R.   +7 more
europepmc   +1 more source