Results 231 to 240 of about 144,255 (280)

Mitochondrial Metabolic Reprogramming in Glioma: Mechanisms of Tumorigenesis and Implications for Clinical Therapy

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
In gliomas, mitochondria integrate glucose, lipid, protein, and nucleotide metabolism to support proliferation, invasion, treatment resistance, and adaptation, with D‐2‐hydroxyglutarate‐driven remodeling in IDH‐mutant tumors and diverse metabolic states in IDH wild‐type glioblastomas.
Liangqi Jiang   +4 more
wiley   +1 more source

Skeletal Muscle Transcriptomic Responses to Concurrent Training With Polyphenols in Ageing Adults: A Randomized Trial

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Transcriptomic adaptations of ageing skeletal muscle to concurrent resistance training (RT) and high‐intensity interval training (HIIT) remain insufficiently characterized. We investigated the effects of a 12‐week concurrent RT + HIIT intervention on the vastus lateralis transcriptome in middle‐aged and older adults and whether ...
A. Guadalupe‐Grau   +11 more
wiley   +1 more source

Evaluating Plasma‐Handling Effects on Extracellular Vesicle RNA Yield and Cargo Profiles in Fish: A Methodological Insight

open access: yesJournal of Extracellular Biology, Volume 5, Issue 10, October 2026.
Experimental Design Overview Illustration to visualize the experimental structure (can be included in a graphical abstract later on)—Diagram / Workflow showing fish plasma collection, sample conditions: (a) volume groups (1 mL vs 2 mL or Midi vs Maxi); (b) Fresh vs frozen EV isolation→RNA extraction→Sequencing pipeline.
Antonio Espuela‐Ortiz   +5 more
wiley   +1 more source

Guanine nucleotides drive ribosome biogenesis and glycolytic reprogramming in acute myeloid leukemia stem cells.

open access: yesBlood
Kawano G   +15 more
europepmc   +1 more source

FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia. [PDF]

open access: yesSci Adv
Li W   +10 more
europepmc   +1 more source

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