Results 271 to 280 of about 88,539 (283)

Nascent polypeptide chains on mitochondrial ribosomes and their integration into the inner membrane [PDF]

, 1974
Kroon, Albertus M., Michel, Rainer, Neupert, Walter, Saccone, C.   +3 more
core  

NRF2 signalling in cytoprotection and metabolism

British Journal of Pharmacology, Volume 183, Issue 1, Page 101-114, January 2026.
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi   +4 more
wiley   +1 more source

An ISR-independent role of GCN2 prevents excessive ribosome biogenesis and mRNA translation. [PDF]

Life Sci Alliance
Román-Trufero M, Kleijn IT, Blighe K, Zhou J, Saavedra-García P, Gaffar A, Christoforou M, Bellotti A, Abrahams J, Atrih A, Lamont D, Gierlinski M, Jayaprakash P, Michel AM, Aboagye EO, Yuneva M, Masson GR, Shahrezaei V, Auner HW.   +18 more
europepmc   +1 more source

Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications

British Journal of Pharmacology, Volume 183, Issue 2, Page 379-392, January 2026.
Comparative metabolomic and transcriptomic profiling reveals distinct metabolic shifts and reduced proliferation in 3D MSC spheroids, providing insights to optimise MSC‐based therapies. Abstract Background and Purpose Mesenchymal stem cells (MSCs) are used widely in regenerative medicine due to their multipotency and immunomodulatory properties ...
Manju Shrestha, Yun‐Seo Kil, Yunju Jo, Simmyung Yook, Ki Hyun Kim, Dongryeol Ryu, Joo‐Won Nam, Jee‐Heon Jeong   +7 more
wiley   +1 more source

Identification of polyphosphate-binding proteins in <i>Escherichia coli</i> uncovers targets involved in translation control and ribosome biogenesis. [PDF]

mBio
Baijal K, Kore B, Abramchuk I, Denoncourt A, Han S, Simms A, Dagenais A, Long AR, Rudner AD, Lavallée-Adam M, Gray MJ, Downey M.   +11 more
europepmc   +1 more source

Tumor‐Derived Prostaglandin E2 Promotes Colorectal Cancer Progression by Inducing N2‐Type TAN Polarization

Cancer Science, Volume 117, Issue 1, Page 19-32, January 2026.
We demonstrated that PGE2 released from LDs in CRC cells plays important roles in N2‐type TANs polarization. PGE2 enters neutrophils through its receptor EP2/EP4 to stimulate ROS‐mediated FOXO3a methylation, thereby increasing the polarization of N2‐type TANs.
Yue Han, Wen Chen, Bin Zhang, Shuang Wang   +3 more
wiley   +1 more source

Yeast cell size control: an interplay among ribosome biogenesis, protein synthesis and MAPK routes

, 2011
Mariele Viganò
openalex   +1 more source

Inhibition of Ribosome Biogenesis In Vivo Causes p53-Dependent Death and p53-Independent Dysfunction. [PDF]

Cell Mol Gastroenterol Hepatol
Cho CJ, Nguyen T, Rougeau AK, Huang YZ, To S, Lin X, Thalalla Gamage S, Meier JL, Mills JC.   +8 more
europepmc   +1 more source

The cancer-testis lncRNA LINC01940 promotes gastric cancer malignant progression and chemoresistance by enhancing ribosome biogenesis via TAF15-mediated NOL11 SUMOylation

Weijie Zang, Irene Oi‐Lin Ng, Zhuang Lu, Xian Gao, Dajun Xing, Guangze Zhang, Lei Liu, Jianfeng Yi, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
openalex   +1 more source

Mitochondrial ribosome biogenesis and redox sensing. [PDF]

FEBS Open Bio
Brischigliaro M, Sierra-Magro A, Ahn A, Barrientos A.   +3 more
europepmc   +1 more source