Recombinant anti-HIV MAP30, a ribosome inactivating protein: against plant virus and bacteriophage [PDF]
Scientific Reports, 2023 The ribosome inactivating proteins (RIPs) efficiently decrease the microbial infections in plants. Momordica charantia MAP30 is a type I RIP that has not been investigated against plant viruses or bacteriophages.
Nafiseh Amirzadeh +3 more
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In-silico analysis of ribosome inactivating protein (RIP) of the Cucurbitaceae family [PDF]
AMB ExpressRibosome-inactivating proteins (RIPs) are highly active N-glycosidases that depurinate both bacterial and eukaryotic rRNAs, halting protein synthesis during translation.
Quratulain Maqsood +5 more
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Structure and Activity of a Cytosolic Ribosome-Inactivating Protein from Rice [PDF]
Toxins, 2019 Ribosome-inactivating proteins (RIPs) are cytotoxic enzymes that inhibit protein translation by depurinating ribosomal RNA. Although most plant RIPs are synthesized with leader sequences that sequester them away from the host ribosomes, several RIPs from
Jeroen De Zaeytijd +3 more
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Revising the taxonomic distribution, origin and evolution of ribosome inactivating protein genes. [PDF]
PLoS ONE, 2013 Ribosome inactivating proteins are enzymes that depurinate a specific adenine residue in the alpha-sarcin-ricin loop of the large ribosomal RNA, being ricin and Shiga toxins the most renowned examples.
Walter J Lapadula +2 more
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Metazoan Ribosome Inactivating Protein encoding genes acquired by Horizontal Gene Transfer [PDF]
Scientific Reports, 2017 Ribosome inactivating proteins (RIPs) are RNA N-glycosidases that depurinate a specific adenine residue in the conserved sarcin/ricin loop of 28S rRNA.
Walter J. Lapadula +4 more
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Cytotoxicity Effect of Quinoin, Type 1 Ribosome-Inactivating Protein from Quinoa Seeds, on Glioblastoma Cells [PDF]
Toxins, 2021 Ribosome-inactivating proteins (RIPs) are found in several edible plants and are well characterized. Many studies highlight their use in cancer therapy, alone or as immunoconjugates, linked to monoclonal antibodies directed against target cancer cells ...
Rossella Rotondo +7 more
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Overexpression of the ribosome-inactivating protein OsRIP1 modulates the jasmonate signaling pathway in rice [PDF]
Frontiers in Plant ScienceRibosome-inactivating proteins (RIPs) are plant enzymes that target the rRNA. The cytoplasmic RIP, called OsRIP1, plays a crucial role in regulating jasmonate, a key plant hormone.
Simin Chen +10 more
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Primary Sequence and Three-Dimensional Structural Comparison between Malanin and Ricin, a Type II Ribosome-Inactivating Protein [PDF]
ToxinsMalanin is a new type II ribosome-inactivating protein (RIP) purified from Malania oleifera, a rare, endangered tree is only found in the southwest of Guangxi Province and the southeast of Yunnan Province, China.
Yan Yuan, Shuxiao Wu, Philip J. R. Day
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A ribosome-inactivating protein in a Drosophila defensive symbiont. [PDF]
Proc Natl Acad Sci U S A, 2016 Significance Symbioses between animals and microbes are now recognized as critical to many aspects of host health. This is especially true in insects, which are associated with diverse maternally transmitted endosymbionts that can protect against parasites and pathogens.
Hamilton PT +3 more
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Structure of Ribosome-Inactivating Protein from Mirabilis jalapa and Its L12-Stalk-Dependent Inhibition of Escherichia coli Ribosome [PDF]
ToxinsMirabilis antiviral protein (MAP) is the type I ribosome-inactivating protein (RIP), which consists of an RNA N-glycosylase domain with no carbohydrate-binding domain.
Nanami Nishida +7 more
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