Results 101 to 110 of about 1,593,838 (216)

Advances in research on autophagy in the maintenance of insect–microbe symbiosis

open access: yesNew Plant Protection, EarlyView.
Autophagy plays a dual regulatory role in insect–microbe symbiotic relationships. Beneficial symbiotic bacteria in insects participate in nutrient exchange via the TOR pathway, whereas pathogenic microbes induce immune defense through the AMPK pathway. Autophagy‐related genes regulate development and pathogen clearance during this process.
Yanbin Wang   +5 more
wiley   +1 more source

Ribosome-inactivating protein-containing conjugates for therapeutic use

open access: yes, 2010
A number of plant proteins inhibit protein synthesis by irreversibly inactivating the 60S ribosomal subunit in a catalytical, that is, enzymatic, manner. For this property, they are called ribosome-inactivating proteins (RIPs).
COLOMBATTI, Marco   +2 more
core   +1 more source

Enterovirus infections in children

open access: yesPediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen   +11 more
wiley   +1 more source

A Ribosome–Inactivating Protein fromAmaranthus viridis

open access: yesBioscience, Biotechnology, and Biochemistry, 1997
An antiviral protein purified from the leaves of Amaranthus viridis was named amaranthin. The in vivo antiviral activity of amaranthin was confirmed in tobacco mosaic virus (TMV) infection test on Nicotiana glutinosa leaves. The molecular mass of the amaranthin was estimated about 30 kDa by SDS-PAGE and the pI was measured as 9.8 by isoelectric ...
KWON, Seok-Yoon   +3 more
openaire   +2 more sources

Supervised Protein Structure Classification Using Topological Persistence With DeltaFold

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Recent advances in protein structure prediction have considerably increased the number of available structures, underscoring the need for scalable and accurate methods to compare and classify this huge amount of data. Current approaches based on sequence alignment or structural superposition often lack sensitivity and/or are computationally ...
Joseph Nardin‐Gennequin   +3 more
wiley   +1 more source

Review of the ethnobotany, phytochemistry, pharmacology, and toxicity studies of the genus Adenia

open access: yesFrontiers in Pharmacology
BackgroundThe genus Adenia has a rich history of traditional medicinal use across various cultures, particularly in Africa and parts of Asia. The present review summarizes key features of the genus Adenia, focusing on its occurrence, distribution ...
Iliassou L. Mouafon, David R. Katerere
doaj   +1 more source

Inhibition of post-transcriptional steps in ribosome biogenesis confers cytoprotection against chemotherapeutic agents in a p53-dependent manner

open access: yesScientific Reports, 2017
The p53-mediated nucleolar stress response associated with inhibition of ribosomal RNA transcription was previously shown to potentiate killing of tumor cells. Here, we asked whether targeting of ribosome biogenesis can be used as the basis for selective
Russell T. Sapio   +6 more
doaj   +1 more source

Structure and Biological Properties of Ribosome-Inactivating Proteins and Lectins from Elder (Sambucus nigra L.) Leaves. [PDF]

open access: yesToxins (Basel), 2022
Iglesias R   +8 more
europepmc   +1 more source

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