Results 41 to 50 of about 1,593,838 (216)
Protein folding on the ribosome studied using NMR spectroscopy [PDF]
, 2013 NMR spectroscopy is a powerful tool for the investigation of protein folding and misfolding, providing a characterization of molecular structure, dynamics and exchange processes, across a very wide range of timescales and with near atomic resolution.
Christodoulou, J +9 more
core +1 more source
Toxins, 2015 Ribosome inactivating proteins (RIPs) inhibit protein synthesis by depurinating the large ribosomal RNA and some are found to possess anti-human immunodeficiency virus (HIV) activity. Maize ribosome inactivating protein (RIP) has an internal inactivation
Rui-Rui Wang +13 more
doaj +1 more source
Ribosome inactivation by Escherichia coli GTPase RsgA inhibits T4 phage
Frontiers in Microbiology, 2023 IntroductionBacteria must combat phages, and myriad bacterial anti-phage systems have been discovered that reduce host metabolism, for example, by depleting energetic compounds like ATP and NAD+. Hence, these systems indirectly inhibit protein production.
Laura Fernández-García +3 more
doaj +1 more source
Toxins, 2023 Ageritin from poplar mushrooms is a specific endonuclease that hydrolyzes a single phosphodiester bond located in the sarcin-ricin loop (SRL) of the large rRNA, thereby blocking protein synthesis.
Sara Ragucci +4 more
doaj +1 more source
2A-induced ribosome stalling [PDF]
, 2014 Originally 2A was characterised in foot-and-mouth disease virus. Site directed mutagenesis identified a C-terminus consensus motif [D(V/I)ExNPGP] and it is proposed that 2A interacts with the exit tunnel of the ribosome in a way that a specific peptide ...
Odon, Valèrie
core +1 more source
Saporins - Type 1 Ribosome-inactivating proteins from soapwort (saponaria officinalis L.) [PDF]
, 1995 Ribosome-inactivating proteins (RlPs) are found distributed throughout the plant kingdom. These proteins possess a RNA N-glycosidase activity whereby the depurination of a specific adenine residue from the large ribosomal subunit renders eukaryotic and ...
Sinclair, Lesley Jean
core
The small-subunit processome is a ribosome assembly intermediate [PDF]
, 2004 The small-subunit (SSU) processome is a large ribonucleoprotein required for the biogenesis of the 18S rRNA and likely corresponds to the terminal knobs visualized by electron microscopy on the 5' end of nascent rRNAs.
Granneman, Sander; id_orcid +4 more
core +1 more source
Plant proteins that inactivate foreign ribosomes
Bioscience Reports, 1986 Ribosome-inactivating proteins are a group of closely related proteins that are widely distributed throughout the plant kingdom and which share the unusual property of being able to inactivate mammalian ribosomes by an enzymic (non-stoichiometric) mechanism (1). Two major classes of these proteins are found in plants.
W K, Roberts, C P, Selitrennikoff
openaire +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Gene sequences encoding ribosome-inactivating proteins from soapwort (Saponaria officinalis L.) [PDF]
, 1991 Ribosome-inactivating proteins (RIPs) are found in a wide variety of plant species. They possess an RNA N-glycosidase activity whereby the removal of a specific adenine residue from 28 S RNA renders a eukaryotic ribosome inactive.
Fordham-Skelton, Anthony P.
core