Results 141 to 150 of about 43,196 (233)

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan   +9 more
wiley   +1 more source

Ribosome Profiling Reveals Translational Reprogramming via mTOR Activation in Omacetaxine-Resistant Multiple Myeloma. [PDF]

open access: yesMol Cancer Res
Walker ZJ   +10 more
europepmc   +1 more source

Variational inference for detecting differential translation in ribosome profiling studies. [PDF]

open access: yesFront Genet, 2023
Walker DC   +5 more
europepmc   +1 more source

Targeting the Dynamic Susceptibility Window: Time‐Sensitive Photodynamic Synergy With Antibiotics Against Streptococcus spp

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Objective Evaluated the antimicrobial efficacy of curcumin‐mediated photodynamic inactivation (PDI) against both sensitive and resistant strains of Streptococcus pneumoniae and Streptococcus pyogenes, as well as its potential to enhance antibiotic effects (amoxicillin, ceftriaxone, erythromycin).
Isabella S. Gonçalves   +3 more
wiley   +1 more source

Ribosome Profiling for Biomarker Discovery

open access: yesJapanese Journal of Complementary and Alternative Medicine, 2013
Hiroaki SAKO   +2 more
openaire   +2 more sources

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu   +4 more
wiley   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

open access: yesMed Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li   +8 more
wiley   +1 more source

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