Results 241 to 250 of about 78,844 (296)

The differences in local translatome across distinct neuron types is mediated by both baseline cellular differences and post-transcriptional mechanisms [PDF]

, 2018
Aryal, Shivani, Dougherty, Joseph D, Lagunas, Tomas, Lake, Allison M, Ouwenga, Rebecca   +4 more
core   +1 more source

H2‐dependent modulation of tetrahydromethanopterin S‐methyltransferase (Mtr complex) activity by the small protein MtrR in Methanosarcina mazei

The FEBS Journal, EarlyView.
Small protein MtrR is a regulator of the Mtr methyltransferase complex in Methanosarcina mazei. It binds specifically to the MtrA subunit and modulates Mtr activity in response to hydrogen (H2) availability. Deleting mtrR impairs growth in the presence but not absence of H2, indicating its role in directing methyl transfer toward an energy‐conserving ...
Tim Habenicht, Bjarne Hastedt, Liam Cassidy, Claudia Kießling, Andreas Tholey, Jan M. Schuller, Ruth A. Schmitz   +6 more
wiley   +1 more source

A rapid protocol for ribosome profiling of low input samples

, 2022
Meindl A, Romberger M, Lehmann G, Eichner N, Kleemann L, Wu J, Danner J, Boesl M, Mesitov M, Meister G, König J, Leidel S, Medenbach J.   +12 more
europepmc   +1 more source

Contrasting effects of different molecular crowding environments on base‐pair opening/closing dynamics of DNA triplex structures

The FEBS Journal, EarlyView.
Base‐pair opening and closing regulate nucleic‐acid structure, stability, and function, but how these motions behave under intracellular molecular crowding remains unclear. Using NMR, we quantified these dynamics in a DNA triplex under two crowder‐reconstituted environments that mimic cellular crowding.
Tomoki Sakamoto, Yudai Yamaoki, Takashi Nagata, Masato Katahira   +3 more
wiley   +1 more source

Widespread stable noncanonical peptides identified by integrated analyses of ribosome profiling and ORF features. [PDF]

Nat Commun
Yang H, Li Q, Stroup EK, Wang S, Ji Z.
europepmc   +1 more source

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

Ribosome profiling reveals the role of yeast RNA-binding proteins Cth1 and Cth2 in translational regulation. [PDF]

iScience
Barlit H, Romero AM, Gülhan A, Patnaik PK, Tyshkovskiy A, Martínez-Pastor MT, Gladyshev VN, Puig S, Labunskyy VM.   +8 more
europepmc   +1 more source

choros: correction of sequence-based biases for accurate quantification of ribosome profiling data

, 2023
Mok A, Tunney R, Benegas G, Wallace EWJ, Lareau LF.   +4 more
europepmc   +1 more source

Efficacy and Safety of Quadruple Therapy With Semisynthetic Tetracycline for Helicobacter pylori Eradication: A Meta‐Analysis

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background High antibiotic resistance and limited tetracycline accessibility severely restrict the clinical application of classic bismuth quadruple therapy (BQT), creating an urgent demand for alternative regimens. Methods A systematic search was conducted in PubMed, Embase, Cochrane Library, and Web of Science up to June 3, 2025, for trials ...
Qi‐Qi Guo, Ju Zhang, Xiao‐Jing Zhu, Wei‐Yue Li, Dan‐Yang Zhao, Meng‐Qi Liang, Rong Yan, Yong‐Quan Shi   +7 more
wiley   +1 more source

Electron microscopy‐based three‐dimensional subcellular imaging of plant male gametophyte

Journal of Integrative Plant Biology, EarlyView.
The Aquilos2 Cryo‐FIB workflows provide practical routes for cryo‐electron tomography and volume imaging in plant structural biology. ABSTRACT Understanding cellular events in three dimensions (3D) is of great importance for the annotation and illustration of biological processes in a contextual way. Imaging techniques based on electron microscopy (EM),
Zhiqi Liu, Zizhen Liang, Mengfei Liao, Yixin Huang, Rui Ma, Jiayang Gao, Weiqi Wang, Tao Ni, Philipp S. Erdmann, Liwen Jiang   +9 more
wiley   +1 more source