Results 11 to 20 of about 254,640 (401)
Specialized ribosomes: a new frontier in gene regulation and organismal biology
Nature Reviews Molecular Cell Biology, 2012 Shifeng Xue, Maria Barna
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Ribosomes are optimized for autocatalytic production
Nature, 2017 Shlomi Reuveni +2 more
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Ribosome-omics of the human ribosome [PDF]
RNA, 2014 The torrent of RNA-seq data becoming available not only furnishes an overview of the entire transcriptome but also provides tools to focus on specific areas of interest. Our focus on the synthesis of ribosomes asked whether the abundance of mRNAs encoding ribosomal proteins (RPs) matched the equimolar need for the RPs in the assembly of ribosomes.
Jonathan R. Warner, Varun Gupta
openaire +3 more sources
Lessons in aging from Myc knockout mouse models
Frontiers in Cell and Developmental Biology, 2023 Despite MYC being among the most intensively studied oncogenes, its role in normal development has not been determined as Myc−/− mice do not survival beyond mid-gestation.
Edward V. Prochownik +4 more
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Peptidyl tRNA Hydrolase Is Required for Robust Prolyl-tRNA Turnover in Mycobacterium tuberculosis
mBio, 2023 Enzymes involved in rescuing stalled ribosomes and recycling translation machinery are ubiquitous in bacteria and required for growth. Peptidyl tRNA drop-off is a type of abortive translation that results in the release of a truncated peptide that is ...
Francesca G. Tomasi +8 more
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Mutations in RPS19 may affect ribosome function and biogenesis in Diamond Blackfan anemia
FEBS Open Bio, 2022 Ribosomes, the cellular organelles translating the genetic code to proteins, are assemblies of RNA chains and many proteins (RPs) arranged in precise fine‐tuned interwoven structures.
Disha‐Gajanan Hiregange +5 more
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Ribosomal Biogenesis and Heterogeneity in Development, Disease, and Aging
Epigenomes, 2023 Although reported in the literature, ribosome heterogeneity is a phenomenon whose extent and implications in cell and organismal biology is not fully appreciated.
Rowshan Ara Islam, Charalampos Rallis
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Liver X Receptor β Related to Tumor Progression and Ribosome Gene Expression in Papillary Thyroid Cancer [PDF]
Endocrinology and Metabolism, 2020 Background Intracellular lipid deposition has been reported in thyroid glands in obese animal and human. To understand the regulatory mechanism of lipid metabolism in thyroid cancer, we investigated the expression status of liver X receptor (LXR) and ...
Seonhyang Jeong +5 more
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Structure of Gcn1 bound to stalled and colliding 80S ribosomes
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance There is growing evidence that collisions between ribosomes represent a cellular signal for activating multiple stress pathways, such as ribosome-associated quality control (RQC), the ribotoxic stress response, and the integrated stress ...
A. Pochopien +6 more
semanticscholar +1 more source