Results 11 to 20 of about 109,573 (267)
Regulation of Translation by Lysine Acetylation in Escherichia coli
mBio, 2022 Nε-lysine acetylation is a common posttranslational modification observed in diverse species of bacteria. Aside from a few central metabolic enzymes and transcription factors, little is known about how this posttranslational modification regulates ...
Sarah C. Feid +5 more
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Microbiology Spectrum, 2022 Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen that presents great health concerns. Treatment requires the use of last-line antibiotics, such as members of the oxazolidinone family, of which linezolid is the first member to ...
Laura Perlaza-Jiménez +9 more
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Sequence and expression of a microspore cDNA clone with homology to a ribosomal protein
Acta Societatis Botanicorum Poloniae, 2014 A cDNA library was made to RNA from corn anthers containing developing pollen at the uninucleate microspore stage. A randomly selected clone from this library which contained an insert (531 bp) was isolated and sequenced.
Michael P. Turcich +3 more
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Modeling Cell-Free Protein Synthesis Systems—Approaches and Applications
Frontiers in Bioengineering and Biotechnology, 2020 In vitro systems are ideal setups to investigate the basic principles of biochemical reactions and subsequently the bricks of life. Cell-free protein synthesis (CFPS) systems mimic the transcription and translation processes of whole cells in a ...
Jan Müller +2 more
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Principles of cellular resource allocation revealed by condition-dependent proteome profiling
eLife, 2017 Growing cells coordinate protein translation with metabolic rates. Central to this coordination is ribosome production. Ribosomes drive cell growth, but translation of ribosomal proteins competes with production of non-ribosomal proteins.
Eyal Metzl-Raz +5 more
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Crystals, 2017 The crystal structure of the 92-nucleotide L1-specific fragment of 23S rRNA from Haloarcula marismortui (Hma) has been determined at 3.3 Å resolution.
Azat Gabdulkhakov +5 more
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Frontiers in Physiology, 2021 Skeletal muscle adaptations to resistance and endurance training include increased ribosome and mitochondrial biogenesis, respectively. Such adaptations are believed to contribute to the notable increases in hypertrophy and aerobic capacity observed with
Paulo H. C. Mesquita +8 more
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Ribosomal Biogenesis and Heterogeneity in Development, Disease, and Aging
Epigenomes, 2023 Although reported in the literature, ribosome heterogeneity is a phenomenon whose extent and implications in cell and organismal biology is not fully appreciated.
Rowshan Ara Islam, Charalampos Rallis
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Basic, simple and extendable kinetic model of protein synthesis
Mathematical Biosciences and Engineering, 2019 Protein synthesis is one of the most fundamental biological processes. Despite existence of multiple mathematical models of translation, surprisingly, there is no basic and simple chemical kinetic model of this process, derived directly from the detailed
Alexander N. Gorban +3 more
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Macromolecular Structure Assembly as a Novel Antibiotic Target
Antibiotics, 2022 This review discusses the inhibition of macromolecular structure formation as a novel and under-investigated drug target. The disruption of cell wall structures by penicillin-binding protein interactions is one potential target.
Scott Champney
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