Results 31 to 40 of about 188,934 (259)

Ribosomal Biogenesis and Heterogeneity in Development, Disease, and Aging

open access: yesEpigenomes, 2023
Although reported in the literature, ribosome heterogeneity is a phenomenon whose extent and implications in cell and organismal biology is not fully appreciated.
Rowshan Ara Islam, Charalampos Rallis
doaj   +1 more source

Stoichiometry and Change of the mRNA Closed-Loop Factors as Translating Ribosomes Transit from Initiation to Elongation [PDF]

open access: yes, 2016
Protein synthesis is a highly efficient process and is under exacting control. Yet, the actual abundance of translation factors present in translating complexes and how these abundances change during the transit of a ribosome across an mRNA remains ...
Chiang, Yueh-Chin   +6 more
core   +4 more sources

Nuclear 80S Ribosomes Present Across the Stages of Cell Cycle in Drosophila Melanogaster Cells

open access: yesUMYU Journal of Microbiology Research, 2023
Nuclear translation has been a subject of controversy between scientists for over 5 decades. Despite the existence of evidence to the contrary, most biologists agree that translation exclusively takes place in the cytoplasm of eukaryotes.
Akilu Abdullahi, Saverio Brogna
doaj   +1 more source

Ribosomal Proteins in Ribosome Assembly

open access: yesBiomolecules
Ribosomes are the cellular machinery responsible for translating mRNA into proteins, a process fundamental to all domains of life from bacteria to eukaryotes [...]
Brigitte Pertschy, Ingrid Zierler
openaire   +4 more sources

Ribosomal trafficking is reduced in Schwann cells following induction of myelination. [PDF]

open access: yes, 2015
Local synthesis of proteins within the Schwann cell periphery is extremely important for efficient process extension and myelination, when cells undergo dramatic changes in polarity and geometry.
Love, James M, Shah, Sameer B
core   +2 more sources

Preparation of Biologically Active Arabidopsis Ribosomes and Comparison with Yeast Ribosomes for Binding to a tRNA-Mimic that Enhances Translation of Plant Plus-Strand RNA Viruses

open access: yesFrontiers in Plant Science, 2013
Isolation of biologically active cell components from multicellular eukaryotic organisms often poses difficult challenges such as low yields and inability to retain the integrity and functionality of the purified compound. We previously identified a cap-
Vera Aleksey Stupina   +1 more
doaj   +1 more source

Antibiotics and the ribosome [PDF]

open access: yesMolecular Microbiology, 2006
SummaryThe ribosome is one of the main antibiotic targets in the cell. Recent years brought important insights into the mode of interaction of antibiotics with the ribosome and mechanisms of antibiotic action. Ribosome crystallography provided a detailed view of the interactions between antibiotics and rRNA.
Tanel, Tenson, Alexander, Mankin
openaire   +2 more sources

The expanding toolkit of translating ribosome affinity purification [PDF]

open access: yes, 2017
Translating ribosome affinity purification is a method initially developed for profiling mRNA from genetically defined cell types in complex tissues. It has been applied both to identify target molecules in cell types that are important for controlling a
Dougherty, Joseph D
core   +2 more sources

Identification and characterization of yeast SNF1 kinase homologs in Leishmania major

open access: yesFrontiers in Molecular Biosciences
BackgroundSucrose Non Fermenting1 (SNF1) constitutes a family of protein kinases conserved in eukaryotes, plants, and fungi. SNF1 has been known to play a crucial role in stress adaptation and metabolism, enabling organisms to respond to changing ...
Gaurav Shoeran   +4 more
doaj   +1 more source

The influence of exogenous spermidine on polysomes and RNase activity in wheat leaves under water stress conditions short communication

open access: yesActa Societatis Botanicorum Poloniae, 2014
It was found that spermidine (5mM) delivered to wheat seedlings through their roots prior to water stress affected the state of polysomes and ribosomes under water stress conditions, which was manifested in stabilization of 80 S ribosomes and in ...
Halina Gniazdowska-Skoczek   +2 more
doaj   +1 more source

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