Results 11 to 20 of about 105,300 (304)

Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]

International Journal of Molecular Sciences, 2021
Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis. Mitochondrial ribosomes (mitoribosomes) perform translation of the proteins essential for the oxidative phosphorylation system. The biogenesis of cytoribosomes and
Pecoraro Annalisa, Pagano Martina, Russo Giulia, Russo Annapina   +3 more
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FMRP regulates neuronal RNA granules containing stalled ribosomes, not where ribosomes stall. [PDF]

Elife
Local protein synthesis is a crucial process that maintains local proteostasis in neurons. A large percentage of mRNAs translated in developing neurons are associated with stalled ribosomes.
Li JT, Amiri M, Kailasam S, Drever L, Sun J, Bohorquez L, Sonenberg N, Ortega J, Sossin WS.   +8 more
europepmc   +2 more sources

Electron Microscope Study Of Mitochondrial 60S and Cytoplasmic 80S Ribosomes From Locusta Migratoria [PDF]

, 1974
Purified mitochondrial ribosomes (60S) have been isolated from locust flight muscle. Purification could be achieved after lysis of mitochondria in 0.055 M MgCl2.
F. Miller, W. Neupert, Neupert, Walter, Miller, Fritz, Kleinow, W., W. Kleinow   +5 more
core   +2 more sources

Ribosome-omics of the human ribosome [PDF]

RNA, 2014
The torrent of RNA-seq data becoming available not only furnishes an overview of the entire transcriptome but also provides tools to focus on specific areas of interest. Our focus on the synthesis of ribosomes asked whether the abundance of mRNAs encoding ribosomal proteins (RPs) matched the equimolar need for the RPs in the assembly of ribosomes.
Gupta, Varun, Warner, Jonathan R.
openaire   +2 more sources

Ribosomal proteins: functions beyond the ribosome [PDF]

Journal of Molecular Cell Biology, 2015
Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition,
Xiang, Zhou, Wen-Juan, Liao, Jun-Ming, Liao, Peng, Liao, Hua, Lu   +4 more
openaire   +2 more sources

The mitochondrial ribosome and ribosomal RNA of the chick [PDF]

FEBS Letters, 1971
Reports have appeared on large molecular weight RNAs associated with the mitochondria of higher organisms. These include HeLa cells [ 1 ] , BHK-2 1 cells [2] , mouse L-cells [3,4] , rat liver [4, S] and Xenopus ovary [6] . This RNA consists of two predominant species found to be 17 S and 13 S by sedimentation [2, 31 .
Rabbitts, Terence H., Work, T.S.
openaire   +2 more sources

The inhibition of ribosomal ribonuclease by bacterial ribosomes [PDF]

Biochemical Journal, 1965
1. A comparison has been made between the ribonuclease activities of untreated ribosomes from Escherichia coli B and Pseudomonas fluorescens and the activities of ribosomes on to which ribosomal ribonuclease from E. coli B has been adsorbed. 2. The normal ribosomes from both species were stable in 5-10mm-Mg(2+) (I0.16) at pH6. The RNA in ribosomes from
H E, Wade, H K, Robinson
openaire   +2 more sources

Comparative assessment of crystallographic and cryo-EM models in the Protein Data Bank. [PDF]

FEBS Open Bio
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Wlodawer A, Rubach P, Dauter Z, Dec W, Brzezinski D, Kulik M, Minor W, Jaskolski M.   +7 more
europepmc   +2 more sources

Mass spectrometry of ribosomes and ribosomal subunits [PDF]

Proceedings of the National Academy of Sciences, 1998
Nanoflow electrospray ionization has been used to introduce intact Escherichia coli ribosomes into the ion source of a mass spectrometer. Mass spectra of remarkable quality result from a partial, but selective, dissociation of the particles within the mass spectrometer.
Benjamin, DR, Robinson, C, Hendrick, J, Hartl, F, Dobson, C   +4 more
openaire   +3 more sources

Specialized Yeast Ribosomes: A Customized Tool for Selective mRNA Translation [PDF]

, 2013
Evidence is now accumulating that sub-populations of ribosomes - so-called specialized ribosomes - can favour the translation of subsets of mRNAs. Here we use a large collection of diploid yeast strains, each deficient in one or other copy of the set of ...
Klausegger, Alfred, Brandl Clemens, Lore Breitenbach-Koller, Clemens Br, Bjoern Wimmer (431586), Mick F, Wimmer, Bjoern, Johann W. Bauer (431583), Manuela Weber, Clemens Brandl, Tuite Mick F., Breitenbach-Koller, Hannelore, Klausegger Alfred, Manuela Weber (431587), Johann W. Bauer, Bauer Johann W., Breitenbach-Koller, Lore, Haubenreisser Olaf, Preiss, Thomas, Breitenbach-Koller Lore, Wimmer Bjoern, Helmut Hintner, Michael Breitenbach, Olaf Haubenreisser (431585), Hintner Helmut, Breitenbach, Michael, Mick F Tuite, Alfred Klausegger, Karl Thomas, Weber Manuela, Karl, Thomas, Hintner, Helmut, Bjoern Wimmer, Haar, Thomas Von der, Haubenreisser, Olaf, von der Haar Tobias, Clemens Brandl (431584), Bauer, Johann W., Johann W Bauer, Breitenbach Michael, Thomas Karl, Mick F. Tuite (266570), Lore Breitenbach-Koller (431591), Michael Breitenbach (46789), Bauer, Johann, Tuite, Mick F., von der Haar, Tobias, Olaf Haubenreisser, Helmut Hintner (431590), Brandl, Clemens, Tobias von der Haar, Tobias von der Haar (80575), Alfred Klausegger (431589), Thomas Karl (431588), Weber, Manuela   +54 more
core   +2 more sources