Results 11 to 20 of about 104,929 (312)
The mitochondrial ribosome and ribosomal RNA of the chick [PDF]
FEBS Letters, 1971 Reports have appeared on large molecular weight RNAs associated with the mitochondria of higher organisms. These include HeLa cells [ 1 ] , BHK-2 1 cells [2] , mouse L-cells [3,4] , rat liver [4, S] and Xenopus ovary [6] . This RNA consists of two predominant species found to be 17 S and 13 S by sedimentation [2, 31 .
Rabbitts, Terence H., Work, T.S.
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Macromolecular Structure Assembly as a Novel Antibiotic Target
Antibiotics, 2022 This review discusses the inhibition of macromolecular structure formation as a novel and under-investigated drug target. The disruption of cell wall structures by penicillin-binding protein interactions is one potential target.
Scott Champney
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The inhibition of ribosomal ribonuclease by bacterial ribosomes [PDF]
Biochemical Journal, 1965 1. A comparison has been made between the ribonuclease activities of untreated ribosomes from Escherichia coli B and Pseudomonas fluorescens and the activities of ribosomes on to which ribosomal ribonuclease from E. coli B has been adsorbed. 2. The normal ribosomes from both species were stable in 5-10mm-Mg(2+) (I0.16) at pH6. The RNA in ribosomes from
H E, Wade, H K, Robinson
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Ribosomal proteins: functions beyond the ribosome [PDF]
Journal of Molecular Cell Biology, 2015 Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition,
Xiang, Zhou +4 more
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mBio, 2022 Bacterial ribosomes are composed of three rRNA and over 50 ribosomal protein (r-protein) molecules. r-proteins are essential for ribosome assembly and structural stability and also participate in almost all ribosome functions.
Kaspar Reier +3 more
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Mass spectrometry of ribosomes and ribosomal subunits [PDF]
Proceedings of the National Academy of Sciences, 1998 Nanoflow electrospray ionization has been used to introduce intact Escherichia coli ribosomes into the ion source of a mass spectrometer. Mass spectra of remarkable quality result from a partial, but selective, dissociation of the particles within the mass spectrometer.
Benjamin, DR +4 more
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Electron Microscope Study Of Mitochondrial 60S and Cytoplasmic 80S Ribosomes From Locusta Migratoria [PDF]
, 1974 Purified mitochondrial ribosomes (60S) have been isolated from locust flight muscle. Purification could be achieved after lysis of mitochondria in 0.055 M MgCl2.
F. Miller +5 more
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Specialized Yeast Ribosomes: A Customized Tool for Selective mRNA Translation [PDF]
, 2013 Evidence is now accumulating that sub-populations of ribosomes - so-called specialized ribosomes - can favour the translation of subsets of mRNAs. Here we use a large collection of diploid yeast strains, each deficient in one or other copy of the set of ...
Klausegger, Alfred +54 more
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The Effects of Deregulated Ribosomal Biogenesis in Cancer
Biomolecules, 2023 Ribosomes are macromolecular ribonucleoprotein complexes assembled from RNA and proteins. Functional ribosomes arise from the nucleolus, require ribosomal RNA processing and the coordinated assembly of ribosomal proteins (RPs), and are frequently ...
Yiwei Lu, Shizhuo Wang, Yisheng Jiao
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Physiochemical properties of rat liver mitochondrial ribosomes [PDF]
, 2001 In the present study, the physiochemical properties of rat liver mitochondrial ribosomes were examined and compared with Escherichia coli ribosomes.
Patel, V., Hantgan, R., Cunningham, C.C.
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