Results 231 to 240 of about 44,034 (296)

Minimal twister sister-like self-cleaving ribozymes in the human genome revealed by deep mutational scanning. [PDF]

Elife
Zhang Z, Hong X, Xiong P, Wang J, Zhou Y, Zhan J.   +5 more
europepmc   +1 more source

Principles of <i>in vitro</i> selection of ribozymes from random sequence libraries. [PDF]

J R Soc Interface
Higgs PG, Muller UF.
europepmc   +1 more source

Computational De Novo Design of Group II Introns Yields Highly Active Ribozymes. [PDF]

Chembiochem
Szokoli D, Nwosu NE, Glatt LM, Mutschler H.   +3 more
europepmc   +1 more source

Expression of the <i>Nicotiana benthamiana</i> Retrozyme 1 (NbRZ1) Genomic Locus. [PDF]

Plants (Basel)
Lezzhov AA, Atabekova AK, Chergintsev DA, Solovyev AG, Morozov SY.   +4 more
europepmc   +1 more source

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Ribozyme-Catalyzed Transcription of an Active Ribozyme

Science, 2011
A functional RNA has been synthesized by an RNA enzyme from mononucleotide building blocks.
James Attwater, Philipp Holliger
exaly   +3 more sources

Charge-density reduction promotes ribozyme activity in RNA–peptide coacervates via RNA fluidization and magnesium partitioning

Nature Chemistry, 2022
It has long been proposed that phase-separated compartments can provide a basis for the formation of cellular precursors in prebiotic environments.
Juan M Iglesias-Artola, Mrityunjoy Kar, Anatol W Fritsch   +2 more
exaly   +2 more sources

Site-specific RNA methylation by a methyltransferase ribozyme

Nature, 2020
Nearly all classes of coding and non-coding RNA undergo post-transcriptional modification, including RNA methylation. Methylated nucleotides are among the evolutionarily most-conserved features of transfer (t)RNA and ribosomal (r)RNA 1 , 2 .
Claudia Höbartner
exaly   +2 more sources

Control of gene expression by a natural metabolite-responsive ribozyme

Nature, 2004
Wade C Winkler, Ali Nahvi, Ronald R Breaker   +2 more
exaly   +2 more sources

How do metal ions direct ribozyme folding?

Nature Chemistry, 2015
Ribozymes, which carry out phosphoryl transfer reactions, often require Mg2+ ions for catalytic activity. The correct folding of the active site and ribozyme tertiary structure is also regulated by metal ions in a manner which is not fully understood ...
Dave Thirumalai
exaly   +2 more sources

Amplification of RNA by an RNA polymerase ribozyme

Proceedings of the National Academy of Sciences of the United States of America, 2016
David P Horning, G. F. Joyce
exaly   +2 more sources